van der Kruijssen CM[au] - Search Results

Year	Number of Results
1991	1
1993	2
1994	1
2005	1
2007	2
2008	4
2009	7
2010	3
2011	1
2022	0

1

ABCC2, ABCC3, and ABCB1, but not CYP3A, Protect against Trabectedin-Mediated Hepatotoxicity.

van Waterschoot RA, Eman RM, Wagenaar E, van der Kruijssen CM, Rosing H, Beijnen JH, Schinkel AH. van Waterschoot RA, et al. Among authors: van der kruijssen cm. Clin Cancer Res. 2009 Dec 15;15(24):7616-7623. doi: 10.1158/1078-0432.CCR-09-2127. Clin Cancer Res. 2009. PMID: 19996204 Free article.

2

High impact of Oatp1a/1b transporters on in vivo disposition of the hydrophobic anticancer drug paclitaxel.

van de Steeg E, van Esch A, Wagenaar E, van der Kruijssen CM, van Tellingen O, Kenworthy KE, Schinkel AH. van de Steeg E, et al. Among authors: van der kruijssen cm. Clin Cancer Res. 2011 Jan 15;17(2):294-301. doi: 10.1158/1078-0432.CCR-10-1980. Epub 2010 Nov 19. Clin Cancer Res. 2011. PMID: 21097690 Free article.

3

Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver.

van Waterschoot RA, Rooswinkel RW, Wagenaar E, van der Kruijssen CM, van Herwaarden AE, Schinkel AH. van Waterschoot RA, et al. Among authors: van der kruijssen cm. FASEB J. 2009 Jan;23(1):224-31. doi: 10.1096/fj.08-114876. Epub 2008 Sep 15. FASEB J. 2009. PMID: 18794335

4

Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1).

van de Steeg E, van der Kruijssen CM, Wagenaar E, Burggraaff JE, Mesman E, Kenworthy KE, Schinkel AH. van de Steeg E, et al. Among authors: van der kruijssen cm. Drug Metab Dispos. 2009 Feb;37(2):277-81. doi: 10.1124/dmd.108.024315. Epub 2008 Nov 20. Drug Metab Dispos. 2009. PMID: 19022939

5

Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to up-regulated CYP2C enzymes.

van Waterschoot RA, van Herwaarden AE, Lagas JS, Sparidans RW, Wagenaar E, van der Kruijssen CM, Goldstein JA, Zeldin DC, Beijnen JH, Schinkel AH. van Waterschoot RA, et al. Among authors: van der kruijssen cm. Mol Pharmacol. 2008 Mar;73(3):1029-36. doi: 10.1124/mol.107.043869. Epub 2007 Dec 21. Mol Pharmacol. 2008. PMID: 18156313 Free PMC article.

6

Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism.

van Herwaarden AE, Wagenaar E, van der Kruijssen CM, van Waterschoot RA, Smit JW, Song JY, van der Valk MA, van Tellingen O, van der Hoorn JW, Rosing H, Beijnen JH, Schinkel AH. van Herwaarden AE, et al. Among authors: van der kruijssen cm. J Clin Invest. 2007 Nov;117(11):3583-92. doi: 10.1172/JCI33435. J Clin Invest. 2007. PMID: 17975676 Free PMC article.

7

Midazolam and cyclosporin a metabolism in transgenic mice with liver-specific expression of human CYP3A4.

van Herwaarden AE, Smit JW, Sparidans RW, Wagenaar E, van der Kruijssen CM, Schellens JH, Beijnen JH, Schinkel AH. van Herwaarden AE, et al. Among authors: van der kruijssen cm. Drug Metab Dispos. 2005 Jul;33(7):892-5. doi: 10.1124/dmd.105.004721. Epub 2005 Apr 21. Drug Metab Dispos. 2005. PMID: 15845749

8

Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

van de Steeg E, Wagenaar E, van der Kruijssen CM, Burggraaff JE, de Waart DR, Elferink RP, Kenworthy KE, Schinkel AH. van de Steeg E, et al. Among authors: van der kruijssen cm. J Clin Invest. 2010 Aug;120(8):2942-52. doi: 10.1172/JCI42168. Epub 2010 Jul 19. J Clin Invest. 2010. PMID: 20644253 Free PMC article.

9

Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.

van Waterschoot RA, Lagas JS, Wagenaar E, van der Kruijssen CM, van Herwaarden AE, Song JY, Rooswinkel RW, van Tellingen O, Rosing H, Beijnen JH, Schinkel AH. van Waterschoot RA, et al. Among authors: van der kruijssen cm. Cancer Res. 2009 Dec 1;69(23):8996-9002. doi: 10.1158/0008-5472.CAN-09-2915. Epub 2009 Nov 17. Cancer Res. 2009. PMID: 19920203 Free article.

10

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, de Waart DR, van de Wetering K, van der Kruijssen CM, Oude Elferink RP, van Tellingen O, Schinkel AH. Vlaming ML, et al. Among authors: van der kruijssen cm. Clin Cancer Res. 2009 May 1;15(9):3084-93. doi: 10.1158/1078-0432.CCR-08-2940. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383815 Free article.

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