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Page 1
RIFM fragrance ingredient safety assessment, decanoic acid, CAS Registry Number 334-48-5.
Api AM, Belsito D, Biserta S, Botelho D, Bruze M, Burton GA Jr, Buschmann J, Cancellieri MA, Dagli ML, Date M, Dekant W, Deodhar C, Fryer AD, Gadhia S, Jones L, Joshi K, Lapczynski A, Lavelle M, Liebler DC, Na M, O'Brien D, Patel A, Penning TM, Ritacco G, Rodriguez-Ropero F, Romine J, Sadekar N, Salvito D, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y, Tsang S. Api AM, et al. Food Chem Toxicol. 2020 Oct 15;144 Suppl 1:111465. doi: 10.1016/j.fct.2020.111465. Epub 2020 Jul 5. Food Chem Toxicol. 2020. PMID: 32640335 Review.
Based on the existing data, decanoic acid does not present a concern for skin sensitization under the current, declared levels of use. The phototoxicity/photoallergenicity endpoints were evaluated based on UV spectra; decanoic acid is not expected to b …
Based on the existing data, decanoic acid does not present a concern for skin sensitization under the current, declared levels …
10-hydroxy decanoic acid, trans-10-hydroxy-2-decanoic acid, and sebacic acid: Source, metabolism, and potential health functionalities and nutraceutical applications.
Liao Z, Alrosan M, Alu'datt MH, Tan TC. Liao Z, et al. J Food Sci. 2024 Jul;89(7):3878-3893. doi: 10.1111/1750-3841.17143. Epub 2024 Jun 12. J Food Sci. 2024. PMID: 38865248 Review.
The popularity of royal jelly (RJ) as a functional food has attracted attention from various industries, especially nutraceuticals, due to the increasing demand from health enthusiasts. Sebacic acid, 10-hydroxy decanoic acid, and trans-10-hydroxy-2-decanoic …
The popularity of royal jelly (RJ) as a functional food has attracted attention from various industries, especially nutraceuticals, due to t …
G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds.
Cooper PO, Kleb SS, Noonepalle SK, Amuso VM, Varshney R, Rudolph MC, Dhaliwal TK, Nguyen DV, Mazumder MF, Babirye NS, Gupta R, Nguyen BN, Shook BA. Cooper PO, et al. Cell Rep. 2024 Jun 25;43(6):114288. doi: 10.1016/j.celrep.2024.114288. Epub 2024 May 29. Cell Rep. 2024. PMID: 38814782 Free PMC article.
GPR84 signaling was identified as a key component of regulating myeloid cell numbers and subsequent tissue repair through in vivo administration of a pharmacological antagonist and the MCFA decanoic acid. We found that impaired injury-induced dermal adipocyte lipoly …
GPR84 signaling was identified as a key component of regulating myeloid cell numbers and subsequent tissue repair through in vivo administra …
Relationship between Dietary Decanoic Acid and Coronary Artery Disease: A Population-Based Cross-Sectional Study.
Wu Z, Yang W, Li M, Li F, Gong R, Wu Y. Wu Z, et al. Nutrients. 2023 Oct 10;15(20):4308. doi: 10.3390/nu15204308. Nutrients. 2023. PMID: 37892384 Free PMC article.
BACKGROUND: Coronary artery disease (CAD) is a cardiovascular disease with significant personal health and socioeconomic consequences. The biological functions of decanoic acid and the pathogenesis of CAD overlap considerably; however, studies exploring their relati …
BACKGROUND: Coronary artery disease (CAD) is a cardiovascular disease with significant personal health and socioeconomic consequences. The b …
Decanoic Acid Stimulates Autophagy in D. discoideum.
Warren EC, Kramár P, Lloyd-Jones K, Williams RSB. Warren EC, et al. Cells. 2021 Oct 29;10(11):2946. doi: 10.3390/cells10112946. Cells. 2021. PMID: 34831171 Free PMC article.
Here, we utilize this model to analyze a role for MCFAs in regulating autophagy. We show that treatment with decanoic acid but not octanoic acid induces autophagosome formation and modulates autophagic flux in high glucose conditions. To investigate this effect, …
Here, we utilize this model to analyze a role for MCFAs in regulating autophagy. We show that treatment with decanoic acid but …
The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells.
Mett J, Müller U. Mett J, et al. Sci Rep. 2021 Mar 17;11(1):6135. doi: 10.1038/s41598-021-85523-9. Sci Rep. 2021. PMID: 33731759 Free PMC article.
Phosphatidylcholine (PC) containing decanoic acid (10:0) (PC10:0/10:0) reduced the cellular H(2)O(2) release in comparison to solvent, L-alpha-Glycerophosphorylcholine and PC containing the long-chain fatty acid (LCFA) arachidic acid (20:0). ...It did not affect the …
Phosphatidylcholine (PC) containing decanoic acid (10:0) (PC10:0/10:0) reduced the cellular H(2)O(2) release in comparison to …
Analysis of the Effects of Food Additives on Porphyromonas gingivalis.
Shinohara M, Maetani M, Kitada C, Nishigami Y, Yazawa A, Kamitani S. Shinohara M, et al. Pathogens. 2022 Jan 4;11(1):65. doi: 10.3390/pathogens11010065. Pathogens. 2022. PMID: 35056013 Free PMC article.
The growth of P. gingivalis was inhibited by 5 mM octanoic acid, 1.25 mM decanoic acid, 1.25% acesulfame K, 0.0625% aspartame, 0.03125% saccharin, and 0.625% sucralose. In addition, these food additives showed bactericidal activity for planktonic P. gingivalis (5 mM …
The growth of P. gingivalis was inhibited by 5 mM octanoic acid, 1.25 mM decanoic acid, 1.25% acesulfame K, 0.0625% aspartame, …
Effect of decanoic acid and 10-hydroxydecanoic acid on the biotransformation of methyl decanoate to sebacic acid.
Sugiharto YEC, Lee H, Fitriana AD, Lee H, Jeon W, Park K, Ahn J, Lee H. Sugiharto YEC, et al. AMB Express. 2018 May 5;8(1):75. doi: 10.1186/s13568-018-0605-4. AMB Express. 2018. PMID: 29730843 Free PMC article.
The presence of decanoic acid, even at a low concentration (0.2 g/L), inhibited the transformation of 10-hydroxydecanoic acid to sebacic acid. Moreover, about 24-32% reduction in the decanoic acid oxidation was observed in the presence of 0.5-1.5 g/L 1 …
The presence of decanoic acid, even at a low concentration (0.2 g/L), inhibited the transformation of 10-hydroxydecanoic acid …
Lipidation Engineering in Daptomycin Biosynthesis.
Ji CH, Park S, Lee K, Je HW, Kang HS. Ji CH, et al. J Am Chem Soc. 2024 Nov 6;146(44):30434-30442. doi: 10.1021/jacs.4c10966. Epub 2024 Oct 28. J Am Chem Soc. 2024. PMID: 39465544
First, swapping the fatty acyl AMP ligase (FAAL) gene dptF with foreign FAAL homologs improved the fatty acyl specificity of the lipidation process for decanoic acid. Then, the introduction of Mycobacterium type I fatty acid synthase operon (MvFAS-Ib/MvAcpS) and Cry …
First, swapping the fatty acyl AMP ligase (FAAL) gene dptF with foreign FAAL homologs improved the fatty acyl specificity of the lipidation …
1,336 results