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Virtual screening of carboxylic acid reductases for biocatalytic synthesis of 6-aminocaproic acid and 1,6-hexamethylenediamine.
Shi K, Li JM, Zhang ZJ, Chen Q, Xu JH, Yu HL. Shi K, et al. Biotechnol Bioeng. 2023 Jul;120(7):1773-1783. doi: 10.1002/bit.28408. Epub 2023 May 2. Biotechnol Bioeng. 2023. PMID: 37130074
The key precursors for nylon synthesis, that is, 6-aminocaproic acid (6-ACA) and 1,6-hexamethylenediamine (HMD), are produced from petroleum-based feedstocks. ...
The key precursors for nylon synthesis, that is, 6-aminocaproic acid (6-ACA) and 1,6-hexamethylenediamine (HMD), are pr …
(125)I-Labeled murine anti-CD20 antigen monoclonal antibody NuB2 conjugated to one or three octaarginine (maleimide-(6-aminocaproic acid)(2)-(D-Arg)(8)-(D-Tyr)) peptide chains.
Chopra A. Chopra A. 2010 Dec 8 [updated 2010 Dec 28]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2010 Dec 8 [updated 2010 Dec 28]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 21210565 Free Books & Documents. Review.
On the basis of these observations, Miyamoto et al. conjugated an octaarginine peptide (maleimide-(6-aminocaproic acid)(2)-(d-Arg)(8)-(d-Tyr); R(8)) to NuB2, a murine anti-CD20 mAb, to evaluate the use of a membrane-anchoring peptide for the enhancement of Ab …
On the basis of these observations, Miyamoto et al. conjugated an octaarginine peptide (maleimide-(6-aminocaproic acid) …
The Efficacy of Mannitol Combined with 6-Aminocaproic Acid in the Treatment of Patients with Cerebral Hemorrhage and Its Impact on Immune Function.
Tian B, Tian B, Zhang Y. Tian B, et al. Evid Based Complement Alternat Med. 2022 Jul 12;2022:7396310. doi: 10.1155/2022/7396310. eCollection 2022. Evid Based Complement Alternat Med. 2022. Retraction in: Evid Based Complement Alternat Med. 2023 Sep 27;2023:9815603. doi: 10.1155/2023/9815603. PMID: 35865345 Free PMC article. Retracted.
Based on the different admission times, the participants were randomly divided into the control group and the study group in a ratio of 1:1. 6-Aminocaproic acid was used to treat patients in the control group, while Mannitol along with 6-aminocaproi
Based on the different admission times, the participants were randomly divided into the control group and the study group in a ratio of 1:1. …
Benzofurazan -based fluorophore for the spectrofluorimetric determination of 6-Aminocaproic acid: Application to spiked human plasma and urine.
Anwer EF, Nour El-Deen DAM, Derayea SM, Omar MA. Anwer EF, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Mar 5;268:120723. doi: 10.1016/j.saa.2021.120723. Epub 2021 Dec 9. Spectrochim Acta A Mol Biomol Spectrosc. 2022. PMID: 34915229
The nucleophilic substitution interaction between the primary amine of 6-aminocaproic acid with 4-chloro-7-nitro benzofurazan (NBD-Cl) generated a yellow product. ...Moreover, the proposed method was extended to determine 6-aminocaproic acid
The nucleophilic substitution interaction between the primary amine of 6-aminocaproic acid with 4-chloro-7-nitro benzof …
One-Pot Biocatalytic Transformation of Adipic Acid to 6-Aminocaproic Acid and 1,6-Hexamethylenediamine Using Carboxylic Acid Reductases and Transaminases.
Fedorchuk TP, Khusnutdinova AN, Evdokimova E, Flick R, Di Leo R, Stogios P, Savchenko A, Yakunin AF. Fedorchuk TP, et al. J Am Chem Soc. 2020 Jan 15;142(2):1038-1048. doi: 10.1021/jacs.9b11761. Epub 2020 Jan 7. J Am Chem Soc. 2020. PMID: 31886667
Production of platform chemicals from renewable feedstocks is becoming increasingly important due to concerns on environmental contamination, climate change, and depletion of fossil fuels. Adipic acid (AA), 6-aminocaproic acid (6-ACA) and 1,6-hexamethylenedia …
Production of platform chemicals from renewable feedstocks is becoming increasingly important due to concerns on environmental contamination …
Metabolic engineering combined with site-directed saturated mutations of alpha-keto acid decarboxylase for efficient production of 6-aminocaproic acid and 1,6-hexamethylenediamine.
Wang T, Ye P, Xu X, Lu M, Zhang X, Li N. Wang T, et al. Biotechnol Bioeng. 2024 Oct;121(10):3329-3337. doi: 10.1002/bit.28795. Epub 2024 Jul 2. Biotechnol Bioeng. 2024. PMID: 38956978
6-Aminocaproic acid (6ACA) and 1,6-hexamethylenediamine (HMDA) are key precursors for nylon synthesis, and both are produced using petroleum-based chemical processes. ...
6-Aminocaproic acid (6ACA) and 1,6-hexamethylenediamine (HMDA) are key precursors for nylon synthesis, and both are pro
Expanding lysine industry: industrial biomanufacturing of lysine and its derivatives.
Cheng J, Chen P, Song A, Wang D, Wang Q. Cheng J, et al. J Ind Microbiol Biotechnol. 2018 Aug;45(8):719-734. doi: 10.1007/s10295-018-2030-8. Epub 2018 Apr 13. J Ind Microbiol Biotechnol. 2018. PMID: 29654382 Review.
Some chemicals like L-pipecolic acid, cadaverine, and 5-aminovalerate already have been obtained at a lab scale. Others like 6-aminocaproic acid, valerolactam, and caprolactam could be produced through a biological and chemical coupling pathway or be synthesi …
Some chemicals like L-pipecolic acid, cadaverine, and 5-aminovalerate already have been obtained at a lab scale. Others like 6-ami
THROMBOLYTIC THERAPY.
DOUGLAS AS, MCNICOL GP. DOUGLAS AS, et al. Proc R Soc Med. 1964 Jul;57(7):609-14. Proc R Soc Med. 1964. PMID: 14178954 Free PMC article. No abstract available.
6-Aminocaproic acid as a linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green.
Hu Q, Wang K, Qiu L. Hu Q, et al. Colloids Surf B Biointerfaces. 2021 Jan;197:111372. doi: 10.1016/j.colsurfb.2020.111372. Epub 2020 Sep 28. Colloids Surf B Biointerfaces. 2021. PMID: 33017715
In this study, we construct a novel amphiphilic mPEG-ACA-ICG conjugate by modifying synthetic heptamethine cyanine derivative ICG-COOH with a hydrophobic linker 6-aminocaproic acid (ACA) and amino-terminal poly(ethylene glycol) (mPEG-NH(2)). The as-prepared m …
In this study, we construct a novel amphiphilic mPEG-ACA-ICG conjugate by modifying synthetic heptamethine cyanine derivative ICG-COOH with …
1,888 results