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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
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1953 1
1954 1
1955 1
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1959 4
1960 3
1961 12
1962 20
1963 79
1964 170
1965 56
1966 2
1973 3
1975 2
1976 16
1977 42
1978 44
1979 47
1980 44
1981 36
1982 32
1983 32
1984 49
1985 43
1986 35
1987 32
1988 33
1989 35
1990 42
1991 24
1992 39
1993 38
1994 30
1995 29
1996 38
1997 30
1998 33
1999 28
2000 36
2001 28
2002 20
2003 31
2004 26
2005 29
2006 38
2007 37
2008 34
2009 23
2010 31
2011 41
2012 30
2013 38
2014 28
2015 32
2016 39
2017 32
2018 35
2019 38
2020 28
2021 23
2022 28
2023 24
2024 12
2025 20
2026 6

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1,909 results

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Page 1
Virtual screening of carboxylic acid reductases for biocatalytic synthesis of 6-aminocaproic acid and 1,6-hexamethylenediamine.
Shi K, Li JM, Zhang ZJ, Chen Q, Xu JH, Yu HL. Shi K, et al. Biotechnol Bioeng. 2023 Jul;120(7):1773-1783. doi: 10.1002/bit.28408. Epub 2023 May 2. Biotechnol Bioeng. 2023. PMID: 37130074
The key precursors for nylon synthesis, that is, 6-aminocaproic acid (6-ACA) and 1,6-hexamethylenediamine (HMD), are produced from petroleum-based feedstocks. ...
The key precursors for nylon synthesis, that is, 6-aminocaproic acid (6-ACA) and 1,6-hexamethylenediamine (HMD), …
(125)I-Labeled murine anti-CD20 antigen monoclonal antibody NuB2 conjugated to one or three octaarginine (maleimide-(6-aminocaproic acid)(2)-(D-Arg)(8)-(D-Tyr)) peptide chains.
Chopra A. Chopra A. 2010 Dec 8 [updated 2010 Dec 28]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2010 Dec 8 [updated 2010 Dec 28]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 21210565 Free Books & Documents. Review.
On the basis of these observations, Miyamoto et al. conjugated an octaarginine peptide (maleimide-(6-aminocaproic acid)(2)-(d-Arg)(8)-(d-Tyr); R(8)) to NuB2, a murine anti-CD20 mAb, to evaluate the use of a membrane-anchoring peptide for the enhancement of Ab …
On the basis of these observations, Miyamoto et al. conjugated an octaarginine peptide (maleimide-(6-aminocaproic acid) …
Hemostatic agents.
Levy JH. Levy JH. Transfusion. 2004 Dec;44(12 Suppl):58S-62S. doi: 10.1111/j.0041-1132.2004.04173.x. Transfusion. 2004. PMID: 15585007 Review. No abstract available.
Enhanced biosynthesis of 6-aminocaproic acid in engineered Escherichia coli with artificial protein cage-organized enzymatic cascades.
Luo R, Hu L, Wang D, Xiao K, Liu X, Kang Y, Wang Q. Luo R, et al. Bioresour Technol. 2025 Sep;431:132641. doi: 10.1016/j.biortech.2025.132641. Epub 2025 May 8. Bioresour Technol. 2025. PMID: 40345342
Microbial synthesis of 6-aminocaproic acid (6-ACA), a key nylon-6 monomer, was the focus of this study. Our previous work on 6-ACA biosynthesis using an artificial iterative carbon-chain-extension cycle showed potential, but the impact of intermediates …
Microbial synthesis of 6-aminocaproic acid (6-ACA), a key nylon-6 monomer, was the focus of this study. Our prev …
Acid-responsive contractile hyaluronic acid-based hydrogel loaded with ginsenoside Rg1 for hemostasis and promotion of gastric wound healing.
Li Y, Li T, Feng J, Liu B, Wang Z, He J, Chen Z, Tao R, Wang H, Fan K, Sun Y, Wang J, Guo B, Zhang G. Li Y, et al. Biomaterials. 2025 Oct;321:123320. doi: 10.1016/j.biomaterials.2025.123320. Epub 2025 Apr 3. Biomaterials. 2025. PMID: 40209592
Hence, a series of pH responsive and good tissue adhesive hydrogels (MA-HA/AA) based on methacryloyl hyaluronic acid (MA-HA) and acryloyl-6-aminocaproic acid (AA) via in situ photo-crosslinking were designed, and anti-inflammatory and pro-healing traditional …
Hence, a series of pH responsive and good tissue adhesive hydrogels (MA-HA/AA) based on methacryloyl hyaluronic acid (MA-HA) and acryloyl- …
Metabolic engineering combined with site-directed saturated mutations of alpha-keto acid decarboxylase for efficient production of 6-aminocaproic acid and 1,6-hexamethylenediamine.
Wang T, Ye P, Xu X, Lu M, Zhang X, Li N. Wang T, et al. Biotechnol Bioeng. 2024 Oct;121(10):3329-3337. doi: 10.1002/bit.28795. Epub 2024 Jul 2. Biotechnol Bioeng. 2024. PMID: 38956978
6-Aminocaproic acid (6ACA) and 1,6-hexamethylenediamine (HMDA) are key precursors for nylon synthesis, and both are produced using petroleum-based chemical processes. ...
6-Aminocaproic acid (6ACA) and 1,6-hexamethylenediamine (HMDA) are key precursors for nylon synthesis, and both are pro …
One-Pot Biocatalytic Transformation of Adipic Acid to 6-Aminocaproic Acid and 1,6-Hexamethylenediamine Using Carboxylic Acid Reductases and Transaminases.
Fedorchuk TP, Khusnutdinova AN, Evdokimova E, Flick R, Di Leo R, Stogios P, Savchenko A, Yakunin AF. Fedorchuk TP, et al. J Am Chem Soc. 2020 Jan 15;142(2):1038-1048. doi: 10.1021/jacs.9b11761. Epub 2020 Jan 7. J Am Chem Soc. 2020. PMID: 31886667
Production of platform chemicals from renewable feedstocks is becoming increasingly important due to concerns on environmental contamination, climate change, and depletion of fossil fuels. Adipic acid (AA), 6-aminocaproic acid (6-ACA) and 1,6-hexamethy …
Production of platform chemicals from renewable feedstocks is becoming increasingly important due to concerns on environmental contamination …
The Efficacy of Mannitol Combined with 6-Aminocaproic Acid in the Treatment of Patients with Cerebral Hemorrhage and Its Impact on Immune Function.
Tian B, Tian B, Zhang Y. Tian B, et al. Evid Based Complement Alternat Med. 2022 Jul 12;2022:7396310. doi: 10.1155/2022/7396310. eCollection 2022. Evid Based Complement Alternat Med. 2022. Retraction in: Evid Based Complement Alternat Med. 2023 Sep 27;2023:9815603. doi: 10.1155/2023/9815603. PMID: 35865345 Free PMC article. Retracted.
Based on the different admission times, the participants were randomly divided into the control group and the study group in a ratio of 1:1. 6-Aminocaproic acid was used to treat patients in the control group, while Mannitol along with 6-aminocaproi …
Based on the different admission times, the participants were randomly divided into the control group and the study group in a ratio of 1:1. …
[Hereditary angioneurotic edema].
Azofra García J, Sastre Domínguez J, Sastre Castillo A. Azofra García J, et al. Rev Clin Esp. 1984 Dec 15-31;175(5-6):181-4. Rev Clin Esp. 1984. PMID: 6085517 Review. Spanish. No abstract available.
1,909 results