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Year Number of Results
1916 1
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1934 4
1935 1
1938 1
1940 1
1941 2
1942 1
1943 2
1944 1
1945 4
1946 20
1947 15
1948 23
1949 15
1950 36
1951 34
1952 28
1953 32
1954 42
1955 31
1956 43
1957 37
1958 42
1959 39
1960 50
1961 26
1962 42
1963 62
1964 87
1965 79
1966 80
1967 96
1968 87
1969 130
1970 104
1971 129
1972 135
1973 128
1974 157
1975 171
1976 173
1977 164
1978 139
1979 170
1980 175
1981 171
1982 227
1983 178
1984 312
1985 445
1986 681
1987 927
1988 1098
1989 1318
1990 1453
1991 1491
1992 1540
1993 1555
1994 1532
1995 1493
1996 1457
1997 1327
1998 1320
1999 1245
2000 1316
2001 1204
2002 1188
2003 1183
2004 1263
2005 1280
2006 1282
2007 1241
2008 1228
2009 1186
2010 1258
2011 1263
2012 1412
2013 1457
2014 1374
2015 1353
2016 1332
2017 1307
2018 1337
2019 1314
2020 1438
2021 1416
2022 1272
2023 1188
2024 1286
2025 177

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51,521 results

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Page 1
Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials.
Greff D, Juhász AE, Váncsa S, Váradi A, Sipos Z, Szinte J, Park S, Hegyi P, Nyirády P, Ács N, Várbíró S, Horváth EM. Greff D, et al. Reprod Biol Endocrinol. 2023 Jan 26;21(1):10. doi: 10.1186/s12958-023-01055-z. Reprod Biol Endocrinol. 2023. PMID: 36703143 Free PMC article. Review.
RESULTS: Twenty-six RCTs were identified, including data of 1691 patients (806 inositol, 311 with placebo, and 509 metformin groups). In patients treated with inositols, the risk (CI: 1.13; 2.85) of having a regular menstrual cycle was found by 1.79 higher than in t …
RESULTS: Twenty-six RCTs were identified, including data of 1691 patients (806 inositol, 311 with placebo, and 509 metformin groups). …
D-Chiro-inositol and PCOS: between myth and reality. The never-ending story.
Cianci A, Vitale SG. Cianci A, et al. Int J Food Sci Nutr. 2022 Aug;73(5):565-570. doi: 10.1080/09637486.2022.2029830. Epub 2022 Jan 20. Int J Food Sci Nutr. 2022. PMID: 35057707 Review.
The literature has confirmed the significant role of inositol therapy in PCOS, with particular reference to Myo-inositol and D-chiro-Inositol. The aim of this review is to clarify the use of inositols for the treatment of PCOS and the recent scientific …
The literature has confirmed the significant role of inositol therapy in PCOS, with particular reference to Myo-inositol and D …
Inositol as putative integrative treatment for PCOS.
Genazzani AD. Genazzani AD. Reprod Biomed Online. 2016 Dec;33(6):770-780. doi: 10.1016/j.rbmo.2016.08.024. Epub 2016 Sep 16. Reprod Biomed Online. 2016. PMID: 27717596 Free article. Review.
As metformin often induces side effects, new integrative strategies have been proposed to treat insulin resistance, such as the use of inositols. Such compounds are mainly represented in humans by two inositol stereoisomers: myo-inositol (MYO) and d-chiro- …
As metformin often induces side effects, new integrative strategies have been proposed to treat insulin resistance, such as the use of in
Inositols in PCOS.
Kamenov Z, Gateva A. Kamenov Z, et al. Molecules. 2020 Nov 27;25(23):5566. doi: 10.3390/molecules25235566. Molecules. 2020. PMID: 33260918 Free PMC article. Review.
(1) Background: Myoinositol (MI) and D-chiro-inositol (DCI) are involved in a number of biochemical pathways within oocytes having a role in oocyte maturation, fertilization, implantation, and post-implantation development. Both inositols have a role in insulin sign …
(1) Background: Myoinositol (MI) and D-chiro-inositol (DCI) are involved in a number of biochemical pathways within oocytes having a …
Inositols: From Established Knowledge to Novel Approaches.
Dinicola S, Unfer V, Facchinetti F, Soulage CO, Greene ND, Bizzarri M, Laganà AS, Chan SY, Bevilacqua A, Pkhaladze L, Benvenga S, Stringaro A, Barbaro D, Appetecchia M, Aragona C, Bezerra Espinola MS, Cantelmi T, Cavalli P, Chiu TT, Copp AJ, D'Anna R, Dewailly D, Di Lorenzo C, Diamanti-Kandarakis E, Hernández Marín I, Hod M, Kamenov Z, Kandaraki E, Monastra G, Montanino Oliva M, Nestler JE, Nordio M, Ozay AC, Papalou O, Porcaro G, Prapas N, Roseff S, Vazquez-Levin M, Vucenik I, Wdowiak A. Dinicola S, et al. Int J Mol Sci. 2021 Sep 30;22(19):10575. doi: 10.3390/ijms221910575. Int J Mol Sci. 2021. PMID: 34638926 Free PMC article. Review.
Myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) are natural compounds involved in many biological pathways. ...Such situations usually occur in association with medical conditions, such as PCOS, or as a consequence of some pharmacological treatments. Based …
Myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) are natural compounds involved in many biological pathways. ...Such …
Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review.
Bizzarri M, Monti N, Piombarolo A, Angeloni A, Verna R. Bizzarri M, et al. Nutrients. 2023 Apr 13;15(8):1875. doi: 10.3390/nu15081875. Nutrients. 2023. PMID: 37111094 Free PMC article. Review.
Noticeably, experimental data have shown that myo-inositol and its most relevant epimer D-chiro-inositol are both necessary to permit a faithful transduction of insulin and of other molecular factors. ...Inositol effects on glucose metabolism and steroid horm …
Noticeably, experimental data have shown that myo-inositol and its most relevant epimer D-chiro-inositol are both necessary to …
From Myo-inositol to D-chiro-inositol molecular pathways.
Kiani AK, Paolacci S, Calogero AE, Cannarella R, Di Renzo GC, Gerli S, Della Morte C, Busetto GM, De Berardinis E, Del Giudice F, Stuppia L, Facchinetti F, Dinicola S, Bertelli M. Kiani AK, et al. Eur Rev Med Pharmacol Sci. 2021 Mar;25(5):2390-2402. doi: 10.26355/eurrev_202103_25279. Eur Rev Med Pharmacol Sci. 2021. PMID: 33755975 Free article. Review.
MATERIALS AND METHODS: We performed an online search in the PubMed database using the following keywords: "inositol", "D-chiro-inositol", "myo-inositol", "neural tube defects and inositol". RESULTS: Inositol requirements are partly met by dietar …
MATERIALS AND METHODS: We performed an online search in the PubMed database using the following keywords: "inositol", "D-chiro-ino
Role of Inositols and Inositol Phosphates in Energy Metabolism.
Chatree S, Thongmaen N, Tantivejkul K, Sitticharoon C, Vucenik I. Chatree S, et al. Molecules. 2020 Nov 1;25(21):5079. doi: 10.3390/molecules25215079. Molecules. 2020. PMID: 33139672 Free PMC article. Review.
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as phytic acid or IP6, with their biological activities received much attention for their role in multiple health beneficial effects. Although their roles in cancer treatme …
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as phytic acid or IP6, with thei …
Inositols in Polycystic Ovary Syndrome: An Overview on the Advances.
Facchinetti F, Unfer V, Dewailly D, Kamenov ZA, Diamanti-Kandarakis E, Laganà AS, Nestler JE, Soulage CO; Group of 'Inositol in PCOS and Reproduction'. Facchinetti F, et al. Trends Endocrinol Metab. 2020 Jun;31(6):435-447. doi: 10.1016/j.tem.2020.02.002. Epub 2020 Mar 9. Trends Endocrinol Metab. 2020. PMID: 32396844 Review.
This review details the physiologic roles of two insulin sensitizers, myo-inositol (MI) and d-chiro-inositol (DCI). In the human ovary, MI is a second messenger of follicle-stimulating hormone (FSH) and DCI is an aromatase inhibitor. ...As impaired intestinal transp …
This review details the physiologic roles of two insulin sensitizers, myo-inositol (MI) and d-chiro-inositol (DCI). In the hum …
Update on the combination of myo-inositol/d-chiro-inositol for the treatment of polycystic ovary syndrome.
Lete I, Martínez A, Lasaga I, Centurión E, Vesga A. Lete I, et al. Gynecol Endocrinol. 2024 Dec;40(1):2301554. doi: 10.1080/09513590.2023.2301554. Epub 2024 Jan 18. Gynecol Endocrinol. 2024. PMID: 38239032 Free article. Review.
In this article, we present a narrative review on the use of inositol in the treatment of polycystic ovary syndrome (PCOS). Of the different inositols that exist, only myo-inositol (MYO) and D-chiro inositol (DCI) have been studied in the treatment of …
In this article, we present a narrative review on the use of inositol in the treatment of polycystic ovary syndrome (PCOS). Of the di …
51,521 results
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