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Expression of DNAM-1 (CD226) on inflammatory monocytes.
Vo AV, Takenaka E, Shibuya A, Shibuya K. Vo AV, et al. Mol Immunol. 2016 Jan;69:70-6. doi: 10.1016/j.molimm.2015.11.009. Epub 2015 Dec 8. Mol Immunol. 2016. PMID: 26675069
In this study, we investigated expression of DNAM-1 on monocyte subsets in mouse peripheral blood and found that only inflammatory monocytes (iMos), but not patrolling monocytes (pMos), expressed high levels of DNAM- …
In this study, we investigated expression of DNAM-1 on monocyte subsets in mouse peripheral blood and found that …
Inflammatory monocytes and NK cells play a crucial role in DNAM-1-dependent control of cytomegalovirus infection.
Lenac Rovis T, Kucan Brlic P, Kaynan N, Juranic Lisnic V, Brizic I, Jordan S, Tomic A, Kvestak D, Babic M, Tsukerman P, Colonna M, Koszinowski U, Messerle M, Mandelboim O, Krmpotic A, Jonjic S. Lenac Rovis T, et al. J Exp Med. 2016 Aug 22;213(9):1835-50. doi: 10.1084/jem.20151899. Epub 2016 Aug 8. J Exp Med. 2016. PMID: 27503073 Free PMC article.
This effect was associated with the increased expression of DNAM-1, whereas TIGIT and CD96 were absent on these cells. ...Blocking of CCL2 or the inhibition of iNOS significantly increased titer of the virus lacking m20.1. In this study, we have demons …
This effect was associated with the increased expression of DNAM-1, whereas TIGIT and CD96 were absent on these cells. …
Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis.
Avouac J, Elhai M, Tomcik M, Ruiz B, Friese M, Piedavent M, Colonna M, Bernhardt G, Kahan A, Chiocchia G, Distler JH, Allanore Y. Avouac J, et al. Ann Rheum Dis. 2013 Jun;72(6):1089-98. doi: 10.1136/annrheumdis-2012-201759. Epub 2012 Nov 17. Ann Rheum Dis. 2013. PMID: 23161903
OBJECTIVE: To investigate the contribution of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of dermal fibrosis on gene inactivation and targeted molecular strategies. METHODS: Human skin expression of DNAM- …
OBJECTIVE: To investigate the contribution of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the developme …
Interleukin-15-activated natural killer cells kill autologous osteoclasts via LFA-1, DNAM-1 and TRAIL, and inhibit osteoclast-mediated bone erosion in vitro.
Feng S, Madsen SH, Viller NN, Neutzsky-Wulff AV, Geisler C, Karlsson L, Söderström K. Feng S, et al. Immunology. 2015 Jul;145(3):367-79. doi: 10.1111/imm.12449. Epub 2015 May 19. Immunology. 2015. PMID: 25684021 Free PMC article.
We studied the interaction between human NK cells and autologous monocyte-derived osteoclasts from healthy donors in vitro. We show that osteoclasts express numerous ligands for receptors present on activated NK cells. ...Suppression of bone erosion requires contact …
We studied the interaction between human NK cells and autologous monocyte-derived osteoclasts from healthy donors in vitro. We show t …
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