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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 2
1984 1
1985 3
1986 2
1987 3
1989 2
1990 7
1991 6
1992 5
1993 8
1994 6
1995 10
1996 2
1997 3
1998 12
1999 8
2000 8
2001 14
2002 10
2003 11
2004 8
2005 8
2006 9
2007 16
2008 14
2009 15
2010 24
2011 24
2012 22
2013 26
2014 24
2015 15
2016 19
2017 18
2018 13
2019 13
2020 21
2021 18
2022 12
2023 24
2024 3

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427 results

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1 article found by citation matching

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Page 1
Decoding cell death signals in liver inflammation.
Brenner C, Galluzzi L, Kepp O, Kroemer G. Brenner C, et al. J Hepatol. 2013 Sep;59(3):583-94. doi: 10.1016/j.jhep.2013.03.033. Epub 2013 Apr 6. J Hepatol. 2013. PMID: 23567086 Free article. Review.
In turn, dying hepatocytes release damage-associated molecular patterns that-upon binding to evolutionary conserved pattern recognition receptors-activate cells of the innate immune system to further stimulate inflammatory responses, hence establishing a highly hepatotoxic feedfo …
In turn, dying hepatocytes release damage-associated molecular patterns that-upon binding to evolutionary conserved pattern recognition rece …
5-Lipoxygenase: mechanisms of regulation.
Rådmark O, Samuelsson B. Rådmark O, et al. J Lipid Res. 2009 Apr;50 Suppl(Suppl):S40-5. doi: 10.1194/jlr.R800062-JLR200. Epub 2008 Nov 5. J Lipid Res. 2009. PMID: 18987389 Free PMC article.
5-lipoxygenase (5-LO) catalyzes two steps in biosynthesis of leukotrienes (LTs), a group of lipid mediators of inflammation derived from arachidonic acid (AA). ...
5-lipoxygenase (5-LO) catalyzes two steps in biosynthesis of leukotrienes (LTs), a group of lipid mediators of inflammation de
Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities.
Efferth T, Oesch F. Efferth T, et al. Semin Cancer Biol. 2022 May;80:39-57. doi: 10.1016/j.semcancer.2020.01.015. Epub 2020 Feb 4. Semin Cancer Biol. 2022. PMID: 32027979 Review.
We conducted a systematic review on the anti-inflammatory and anti-cancer activities of Boswellia species and their chemical ingredients (e.g. 3-O-acetyl-11-keto-beta boswellic acid, alpha- and beta-boswellic acids, 11-keto-beta-boswellic acid and other boswellic acids, lupeolic …
We conducted a systematic review on the anti-inflammatory and anti-cancer activities of Boswellia species and their chemical ingredients (e. …
5-Lipoxygenase: regulation of expression and enzyme activity.
Rådmark O, Werz O, Steinhilber D, Samuelsson B. Rådmark O, et al. Trends Biochem Sci. 2007 Jul;32(7):332-41. doi: 10.1016/j.tibs.2007.06.002. Epub 2007 Jun 18. Trends Biochem Sci. 2007. PMID: 17576065 Review.
5-Lipoxygenase (5-LO) catalyzes the first two steps in the biosynthesis of leukotrienes, a group of pro-inflammatory lipid mediators derived from arachidonic acid. ...Recent advances have expanded our understanding of the regulatory mechanisms underlying the
5-Lipoxygenase (5-LO) catalyzes the first two steps in the biosynthesis of leukotrienes, a group of pro-inflammatory lipid med
Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication.
Horio Y, Sogabe R, Shichiri M, Ishida N, Morimoto R, Ohshima A, Isegawa Y. Horio Y, et al. J Clin Biochem Nutr. 2020 Jan;66(1):36-42. doi: 10.3164/jcbn.19-70. Epub 2020 Jan 1. J Clin Biochem Nutr. 2020. PMID: 32001954 Free PMC article.
Zileuton (5-lipoxygenase inhibitor) and 5-lipoxygenase knockdown reduced the daidzein-induced antiviral effect. ...These results suggest that daidzein regulates virus replication via signal transduction through 5-lipoxygenase produ …
Zileuton (5-lipoxygenase inhibitor) and 5-lipoxygenase knockdown reduced the daidzein-induced antiviral effect. …
Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?
Roos J, Grösch S, Werz O, Schröder P, Ziegler S, Fulda S, Paulus P, Urbschat A, Kühn B, Maucher I, Fettel J, Vorup-Jensen T, Piesche M, Matrone C, Steinhilber D, Parnham MJ, Maier TJ. Roos J, et al. Pharmacol Ther. 2016 Jan;157:43-64. doi: 10.1016/j.pharmthera.2015.11.001. Epub 2015 Nov 6. Pharmacol Ther. 2016. PMID: 26549540 Review.
Furthermore, we found a direct link between the 5-lipoxygenase and Wnt signaling pathways, which is essential for the maintenance of leukemic stem cells. ...We believe that 5-lipoxygenase inhibitors might represent a novel type of Wnt inhibitor activat …
Furthermore, we found a direct link between the 5-lipoxygenase and Wnt signaling pathways, which is essential for the maintena …
TRPV4 contributes to ER stress and inflammation: implications for Parkinson's disease.
Liu N, Bai L, Lu Z, Gu R, Zhao D, Yan F, Bai J. Liu N, et al. J Neuroinflammation. 2022 Jan 29;19(1):26. doi: 10.1186/s12974-022-02382-5. J Neuroinflammation. 2022. PMID: 35093118 Free PMC article.
BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder. Its molecular mechanism is still unclear, and pharmacological treatments are unsatisfactory. ...In the same way, MPTP-decreased procaspase-1, MPTP-increased Interleukin-18 (IL-18), Cyclooxgen …
BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder. Its molecular mechanism is still unclear, and pharm …
Intrinsic 5-lipoxygenase activity regulates migration and adherence of mantle cell lymphoma cells.
Xia C, Sadeghi L, Strååt K, Merrien M, Wright AP, Sander B, Xu D, Österborg A, Björkholm M, Claesson HE. Xia C, et al. Prostaglandins Other Lipid Mediat. 2021 Oct;156:106575. doi: 10.1016/j.prostaglandins.2021.106575. Epub 2021 Jun 8. Prostaglandins Other Lipid Mediat. 2021. PMID: 34116165 Free article.
Human B-lymphocytes express 5-lipoxygenase (5-LOX) and 5-LOX activating protein (FLAP) and can convert arachidonic acid to leukotriene B(4). Mantle cell lymphoma (MCL) cells contain similar amounts of 5-LOX as human neutrophils but the function and mechanism
Human B-lymphocytes express 5-lipoxygenase (5-LOX) and 5-LOX activating protein (FLAP) and can convert arachidonic acid to leu …
On the expression and regulation of 5-lipoxygenase in human lymphocytes.
Jakobsson PJ, Steinhilber D, Odlander B, Rådmark O, Claesson HE, Samuelsson B. Jakobsson PJ, et al. Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3521-5. doi: 10.1073/pnas.89.8.3521. Proc Natl Acad Sci U S A. 1992. PMID: 1314391 Free PMC article.
The expression of arachidonate 5-lipoxygenase (arachidonate:oxygen 5-oxidoreductase, EC 1.13.11.34) and the 5-lipoxygenase-activating protein (FLAP) genes in human tonsillar B cells and lymphoblastoid B-cell lines was demonstrated at the …
The expression of arachidonate 5-lipoxygenase (arachidonate:oxygen 5-oxidoreductase, EC 1.13.11.34) and the 5
Inhibition of 5-lipoxygenase is associated with downregulation of the leukotriene B4 receptor 1/ Interleukin-12p35 pathway and ameliorates sepsis-induced myocardial injury.
Xie S, Qi X, Wu Q, Wei L, Zhang M, Xing Y, Shi W, Chen S, Zeng X, Wang S, Guo H, Deng W. Xie S, et al. Free Radic Biol Med. 2021 Apr;166:348-357. doi: 10.1016/j.freeradbiomed.2021.02.034. Epub 2021 Mar 9. Free Radic Biol Med. 2021. PMID: 33705958
The current study aimed at providing evidence on the cardioprotection of suppression of 5-Lipoxygenase (5-Lox) and identifying the possible mechanism in the mouse model of sepsis. The cecal ligation-perforation (CLP) model was applied to C57BL/6 wild-type (WT …
The current study aimed at providing evidence on the cardioprotection of suppression of 5-Lipoxygenase (5-Lox) and identifying …
427 results