Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 2
1984 1
1985 3
1986 2
1987 3
1989 2
1990 7
1991 8
1992 4
1993 8
1994 6
1995 10
1996 3
1997 5
1998 12
1999 8
2000 9
2001 14
2002 10
2003 10
2004 8
2005 8
2006 10
2007 15
2008 14
2009 15
2010 24
2011 26
2012 21
2013 26
2014 22
2015 16
2016 19
2017 18
2018 13
2019 13
2020 21
2021 19
2022 8
Text availability
Article attribute
Article type
Publication date

Search Results

403 results
Results by year

Citations

1 article found by citation matching

Search results

Filters applied: . Clear all
Page 1
Decoding cell death signals in liver inflammation.
Brenner C, Galluzzi L, Kepp O, Kroemer G. Brenner C, et al. J Hepatol. 2013 Sep;59(3):583-94. doi: 10.1016/j.jhep.2013.03.033. Epub 2013 Apr 6. J Hepatol. 2013. PMID: 23567086 Free article. Review.
In turn, dying hepatocytes release damage-associated molecular patterns that-upon binding to evolutionary conserved pattern recognition receptors-activate cells of the innate immune system to further stimulate inflammatory responses, hence establishing a highly hepatotoxic feedfo …
In turn, dying hepatocytes release damage-associated molecular patterns that-upon binding to evolutionary conserved pattern recognition rece …
5-Lipoxygenase: mechanisms of regulation.
Rådmark O, Samuelsson B. Rådmark O, et al. J Lipid Res. 2009 Apr;50 Suppl(Suppl):S40-5. doi: 10.1194/jlr.R800062-JLR200. Epub 2008 Nov 5. J Lipid Res. 2009. PMID: 18987389 Free PMC article.
5-lipoxygenase (5-LO) catalyzes two steps in biosynthesis of leukotrienes (LTs), a group of lipid mediators of inflammation derived from arachidonic acid (AA). LT antagonists are used in treatment of asthma; more recently a potential role also in atherosclero
5-lipoxygenase (5-LO) catalyzes two steps in biosynthesis of leukotrienes (LTs), a group of lipid mediators of inflamma
5-Lipoxygenase: regulation of expression and enzyme activity.
Rådmark O, Werz O, Steinhilber D, Samuelsson B. Rådmark O, et al. Trends Biochem Sci. 2007 Jul;32(7):332-41. doi: 10.1016/j.tibs.2007.06.002. Epub 2007 Jun 18. Trends Biochem Sci. 2007. PMID: 17576065 Review.
5-Lipoxygenase (5-LO) catalyzes the first two steps in the biosynthesis of leukotrienes, a group of pro-inflammatory lipid mediators derived from arachidonic acid. ...Recent advances have expanded our understanding of the regulatory mechanisms underlyi
5-Lipoxygenase (5-LO) catalyzes the first two steps in the biosynthesis of leukotrienes, a group of pro-inflammatory li
Induction of a 5-lipoxygenase product by daidzein is involved in the regulation of influenza virus replication.
Horio Y, Sogabe R, Shichiri M, Ishida N, Morimoto R, Ohshima A, Isegawa Y. Horio Y, et al. J Clin Biochem Nutr. 2020 Jan;66(1):36-42. doi: 10.3164/jcbn.19-70. Epub 2020 Jan 1. J Clin Biochem Nutr. 2020. PMID: 32001954 Free PMC article.
Moreover, virus replication was regulated by treatment with 5-hydroperoxyeicosatetraenoic acid, a precursor of 5-hydroxyeicosatetraenoic acid and 5-lipoxygenase primary product. These results suggest that daidzein regulates virus replicat …
Moreover, virus replication was regulated by treatment with 5-hydroperoxyeicosatetraenoic acid, a precursor of 5-hydrox …
Intrinsic 5-lipoxygenase activity regulates migration and adherence of mantle cell lymphoma cells.
Xia C, Sadeghi L, Strååt K, Merrien M, Wright AP, Sander B, Xu D, Österborg A, Björkholm M, Claesson HE. Xia C, et al. Prostaglandins Other Lipid Mediat. 2021 Oct;156:106575. doi: 10.1016/j.prostaglandins.2021.106575. Epub 2021 Jun 8. Prostaglandins Other Lipid Mediat. 2021. PMID: 34116165 Free article.
Human B-lymphocytes express 5-lipoxygenase (5-LOX) and 5-LOX activating protein (FLAP) and can convert arachidonic acid to leukotriene B(4). Mantle cell lymphoma (MCL) cells contain similar amounts of 5-LOX as human neutrophils but the function …
Human B-lymphocytes express 5-lipoxygenase (5-LOX) and 5-LOX activating protein (FLAP) and can convert arachidon …
Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?
Roos J, Grösch S, Werz O, Schröder P, Ziegler S, Fulda S, Paulus P, Urbschat A, Kühn B, Maucher I, Fettel J, Vorup-Jensen T, Piesche M, Matrone C, Steinhilber D, Parnham MJ, Maier TJ. Roos J, et al. Pharmacol Ther. 2016 Jan;157:43-64. doi: 10.1016/j.pharmthera.2015.11.001. Epub 2015 Nov 6. Pharmacol Ther. 2016. PMID: 26549540 Review.
Furthermore, we found a direct link between the 5-lipoxygenase and Wnt signaling pathways, which is essential for the maintenance of leukemic stem cells. ...We believe that 5-lipoxygenase inhibitors might represent a novel type of Wnt inhibitor activat …
Furthermore, we found a direct link between the 5-lipoxygenase and Wnt signaling pathways, which is essential for the maintena …
Inhibition of 5-Lipoxygenase-Derived Leukotrienes and Hemiketals as a Novel Anti-Inflammatory Mechanism of Urolithins.
Giménez-Bastida JA, González-Sarrías A, Espín JC, Schneider C. Giménez-Bastida JA, et al. Mol Nutr Food Res. 2020 Jun;64(11):e2000129. doi: 10.1002/mnfr.202000129. Epub 2020 May 4. Mol Nutr Food Res. 2020. PMID: 32306507 Free PMC article.
It is hypothesized that Uro can modulate the biosynthesis of leukocyte-derived inflammatory eicosanoids from the 5-lipoxygenase (5-LOX), cyclooxygenase-2 (COX-2), and 5-LOX/COX-2 pathways, relevant in the onset and progression of IBDs, including 5
It is hypothesized that Uro can modulate the biosynthesis of leukocyte-derived inflammatory eicosanoids from the 5-lipoxygenase
5-Lipoxygenase: enzyme expression and regulation of activity.
Steinhilber D. Steinhilber D. Pharm Acta Helv. 1994 Jul;69(1):3-14. doi: 10.1016/0031-6865(94)90024-8. Pharm Acta Helv. 1994. PMID: 7938075 Review.
During hematopoiesis the competence of these cells for leukotriene biosynthesis is supposed to be upregulated. In mature cells, 5-lipoxygenase activity is tightly regulated and seems to be under the control of additional cellular components. ...This re …
During hematopoiesis the competence of these cells for leukotriene biosynthesis is supposed to be upregulated. In mature cells, 5- …
The biology of 5-lipoxygenase: function, structure, and regulatory mechanisms.
Silverman ES, Drazen JM. Silverman ES, et al. Proc Assoc Am Physicians. 1999 Nov-Dec;111(6):525-36. doi: 10.1046/j.1525-1381.1999.t01-1-99231.x. Proc Assoc Am Physicians. 1999. PMID: 10591081 Review.
5-Lipoxygenase (5-LO) catalyzes the two-step conversion of arachidonic acid to leukotriene A4 (LTA4). ...The biology of 5-LO is reviewed here with an emphasis on enzymatic function, protein and gene structure, essential cofactors, and the many regulato
5-Lipoxygenase (5-LO) catalyzes the two-step conversion of arachidonic acid to leukotriene A4 (LTA4). ...The biology of
Inhibition of 5-lipoxygenase is associated with downregulation of the leukotriene B4 receptor 1/ Interleukin-12p35 pathway and ameliorates sepsis-induced myocardial injury.
Xie S, Qi X, Wu Q, Wei L, Zhang M, Xing Y, Shi W, Chen S, Zeng X, Wang S, Guo H, Deng W. Xie S, et al. Free Radic Biol Med. 2021 Apr;166:348-357. doi: 10.1016/j.freeradbiomed.2021.02.034. Epub 2021 Mar 9. Free Radic Biol Med. 2021. PMID: 33705958
The current study aimed at providing evidence on the cardioprotection of suppression of 5-Lipoxygenase (5-Lox) and identifying the possible mechanism in the mouse model of sepsis. The cecal ligation-perforation (CLP) model was applied to C57BL/6 wild-t …
The current study aimed at providing evidence on the cardioprotection of suppression of 5-Lipoxygenase (5-Lox) and iden …
403 results