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6-Sulfo LacNAc (Slan) as a Marker for Non-classical Monocytes.
Hofer TP, van de Loosdrecht AA, Stahl-Hennig C, Cassatella MA, Ziegler-Heitbrock L. Hofer TP, et al. Front Immunol. 2019 Sep 13;10:2052. doi: 10.3389/fimmu.2019.02052. eCollection 2019. Front Immunol. 2019. PMID: 31572354 Free PMC article. Review.
In the search for an additional marker to better dissect the two subsets we have explored the marker 6-sulfo LacNAc (slan). ...We elaborate herein that the features of slan+ cells are congruent with the features of CD16+ non
In the search for an additional marker to better dissect the two subsets we have explored the marker 6-sulfo
Current Concepts on 6-sulfo LacNAc Expressing Monocytes (slanMo).
Ahmad F, Döbel T, Schmitz M, Schäkel K. Ahmad F, et al. Front Immunol. 2019 May 22;10:948. doi: 10.3389/fimmu.2019.00948. eCollection 2019. Front Immunol. 2019. PMID: 31191513 Free PMC article. Review.
The human mononuclear phagocytes system consists of dendritic cells (DCs), monocytes, and macrophages having different functions in bridging innate and adaptive immunity. Among the heterogeneous population of monocytes the cell surface marker slan ( …
The human mononuclear phagocytes system consists of dendritic cells (DCs), monocytes, and macrophages having different functions in b …
Deciphering the fate of slan(+) -monocytes in human tonsils by gene expression profiling.
Bianchetto-Aguilera F, Tamassia N, Gasperini S, Calzetti F, Finotti G, Gardiman E, Montioli R, Bresciani D, Vermi W, Cassatella MA. Bianchetto-Aguilera F, et al. FASEB J. 2020 Jul;34(7):9269-9284. doi: 10.1096/fj.202000181R. Epub 2020 May 15. FASEB J. 2020. PMID: 32413173
However, their fate and characterization at the transcriptomic level in human tissues are partially understood, often as a consequence of the lack of specific markers allowing their unequivocal identification. The 6-sulfo LacNAc (slan) antigen i …
However, their fate and characterization at the transcriptomic level in human tissues are partially understood, often as a consequence of th …
Transcriptional profiling reveals functional dichotomy between human slan(+) non-classical monocytes and myeloid dendritic cells.
van Leeuwen-Kerkhoff N, Lundberg K, Westers TM, Kordasti S, Bontkes HJ, de Gruijl TD, Lindstedt M, van de Loosdrecht AA. van Leeuwen-Kerkhoff N, et al. J Leukoc Biol. 2017 Oct;102(4):1055-1068. doi: 10.1189/jlb.3MA0117-037R. Epub 2017 Jul 18. J Leukoc Biol. 2017. PMID: 28720687
Human 6-sulfo LacNac-positive (slan(+)) cells have been subject to a paradigm debate. ...Rather, the higher expression levels of complement receptors on their cell surface, together with their high secretion of IL-1beta and IL-6, imply a specifi …
Human 6-sulfo LacNac-positive (slan(+)) cells have been subject to a paradigm debate. ...Rather, the higher expr …