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A human circulating immune cell landscape in aging and COVID-19.
Zheng Y, Liu X, Le W, Xie L, Li H, Wen W, Wang S, Ma S, Huang Z, Ye J, Shi W, Ye Y, Liu Z, Song M, Zhang W, Han JJ, Belmonte JCI, Xiao C, Qu J, Wang H, Liu GH, Su W. Zheng Y, et al. Protein Cell. 2020 Oct;11(10):740-770. doi: 10.1007/s13238-020-00762-2. Epub 2020 Aug 11. Protein Cell. 2020. PMID: 32780218 Free PMC article.
However, a global and detailed characterization of the changes that human circulating immune cells undergo with age is lacking. Here, we combined scRNA-seq, mass cytometry and scATAC-seq to compare immune cell types in peripheral blood
However, a global and detailed characterization of the changes that human circulating immune cells undergo with …
Molecular and cellular immune features of aged patients with severe COVID-19 pneumonia.
Lo Tartaro D, Neroni A, Paolini A, Borella R, Mattioli M, Fidanza L, Quong A, Petes C, Awong G, Douglas S, Lin D, Nieto J, Gozzi L, Franceschini E, Busani S, Nasi M, Mattioli AV, Trenti T, Meschiari M, Guaraldi G, Girardis M, Mussini C, Gibellini L, Cossarizza A, De Biasi S. Lo Tartaro D, et al. Commun Biol. 2022 Jun 16;5(1):590. doi: 10.1038/s42003-022-03537-z. Commun Biol. 2022. PMID: 35710943 Free PMC article.
Aging is a major risk factor for developing severe COVID-19, but few detailed data are available concerning immunological changes after infection in aged individuals. Here we describe main immune characteristics in 31 patients with severe
Aging is a major risk factor for developing severe COVID-19, but few detailed data are available concerning immu