A structure-function approach to optimizing TLR4 ligands for human vaccines.
Clin Transl Immunology. 2016.
PMID: 27990284
Free PMC article.
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A structure-function approach to optimizing TLR4 ligands for human vaccines.
Carter D, Fox CB, Day TA, Guderian JA, Liang H, Rolf T, Vergara J, Sagawa ZK, Ireton G, Orr MT, Desbien A, Duthie MS, Coler RN, Reed SG.
Carter D, et al.
Clin Transl Immunology. 2016 Nov 2;5(11):e108. doi: 10.1038/cti.2016.63. eCollection 2016 Nov.
Clin Transl Immunology. 2016.
PMID: 27990284
Free PMC article.
Adjuvants are combined with vaccine antigens to enhance and modify immune responses, and have historically been primarily crude, undefined entities. Introducing toll-like receptor (TLR) ligands has led to a new generation of adjuvants, with TLR4 ligands being …
Adjuvants are combined with vaccine antigens to enhance and modify immune responses, and have historically been primarily crude, undefined e …
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In silicon desinging of RANKL-targeting vaccine for protection of osteoporosis based on the epitope of Denosumab.
Wu T, Guan B, Luo J, Li L, Zhang B, Yang Z, Tan L, Tao H.
Wu T, et al.
Int Immunopharmacol. 2025 Jan 10;144:113610. doi: 10.1016/j.intimp.2024.113610. Epub 2024 Nov 23.
Int Immunopharmacol. 2025.
PMID: 39580862
Free article.
To address these challenges, vaccine-based approach has been adopted to achieve sustainable protection through induction and maintenance of effective antibodies in mild level over decades. ...This molecule was comprised of 46.5 % of helix, 8.5 % strand and 45.1 % coil, the …
To address these challenges, vaccine-based approach has been adopted to achieve sustainable protection through induction and maintena …
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