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Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate.
Fueller M, Wang DA, Tigyi G, Siess W. Fueller M, et al. Cell Signal. 2003 Apr;15(4):367-75. doi: 10.1016/s0898-6568(02)00117-1. Cell Signal. 2003. PMID: 12618211
Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are serum-borne lipid mediators with potential proinflammatory and atherogenic properties. We studied the effects of LPA and S1P on [Ca(2+)](i), a second messenger of cellular acti
Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are serum-borne lipid mediators with potent
Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate.
Siess W. Siess W. Biochim Biophys Acta. 2002 May 23;1582(1-3):204-15. doi: 10.1016/s1388-1981(02)00173-7. Biochim Biophys Acta. 2002. PMID: 12069830 Review.
Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are potent bioactive phospholipids with specific and multiple effects on blood cells and cells of the vessel wall. ...For example, LPA present in minimally modified LDL
Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are potent bioactive phospholipids with spe
Review of the Third Domain Receptor Binding Fragment of Alphafetoprotein (AFP): Plausible Binding of AFP to Lysophospholipid Receptor Targets.
Mizejewski GJ. Mizejewski GJ. Curr Drug Targets. 2017;18(7):874-886. doi: 10.2174/1389450117666160201105245. Curr Drug Targets. 2017. PMID: 26844573 Review.
The LPLs consist of either sphingosine-1-phosphate or lysophosphatidic acid, and mostly their choline, ethanolamine, serine or inositol derivatives. ...These bioactive paracrine lipid mediators are ubiquitously distributed in tissues and are rel …
The LPLs consist of either sphingosine-1-phosphate or lysophosphatidic acid, and mostly their choline, et …
Lysophospholipids increase IL-8 and MCP-1 expressions in human umbilical cord vein endothelial cells through an IL-1-dependent mechanism.
Lin CI, Chen CN, Chen JH, Lee H. Lin CI, et al. J Cell Biochem. 2006 Nov 1;99(4):1216-32. doi: 10.1002/jcb.20963. J Cell Biochem. 2006. PMID: 16795034
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are both low-molecular-weight lysophospholipid (LPL) ligands which are recognized by the Edg family of G protein-coupled receptors (GPCRs). In endothelial cells, these two liga
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are both low-molecular-weight lysophospholi
Expression of the lysophospholipid receptor family and investigation of lysophospholipid-mediated responses in human macrophages.
Duong CQ, Bared SM, Abu-Khader A, Buechler C, Schmitz A, Schmitz G. Duong CQ, et al. Biochim Biophys Acta. 2004 Jun 1;1682(1-3):112-9. doi: 10.1016/j.bbalip.2004.03.002. Biochim Biophys Acta. 2004. PMID: 15158762
Some of the biological effects of lipoproteins have been attributed to their association with lysophosphatidic acid (LPA), lysophosphatidylcholine (LPC), sphingosine-1-phosphate (S1P) and sphingosylphosphorylcholine (SPC). ...The influence of S1 …
Some of the biological effects of lipoproteins have been attributed to their association with lysophosphatidic acid (LPA), lys …
Lysophosphatidic acid as a regulator of endothelial/leukocyte interaction.
Rizza C, Leitinger N, Yue J, Fischer DJ, Wang DA, Shih PT, Lee H, Tigyi G, Berliner JA. Rizza C, et al. Lab Invest. 1999 Oct;79(10):1227-35. Lab Invest. 1999. PMID: 10532586
Lysophosphatidic acid (LPA) is produced by a variety of activated cell types and acts as an intercellular mediator of processes associated with inflammation and repair including platelets aggregation, and smooth muscle and fibroblast proliferation. How
Lysophosphatidic acid (LPA) is produced by a variety of activated cell types and acts as an intercellular mediat
Bioactive lysophospholipids and mesangial cell intracellular signaling pathways: role in the pathobiology of kidney disease.
Kamanna VS, Bassa BV, Ganji SH, Roh DD. Kamanna VS, et al. Histol Histopathol. 2005 Apr;20(2):603-13. doi: 10.14670/HH-20.603. Histol Histopathol. 2005. PMID: 15736064 Review.
Lysophosphatidic acid (LPA), lyso-phosphatidylcholine (LPC), and sphingosine-1-phosphate (S1P) are major biologically active lysophospholipids (LPLs) that are produced by activated platelets, monocyte/macrophages, and many t
Lysophosphatidic acid (LPA), lyso-phosphatidylcholine (LPC), and sphingosine-1-phosphate (S1P) are major
Lysophospholipids increase ICAM-1 expression in HUVEC through a Gi- and NF-kappaB-dependent mechanism.
Lee H, Lin CI, Liao JJ, Lee YW, Yang HY, Lee CY, Hsu HY, Wu HL. Lee H, et al. Am J Physiol Cell Physiol. 2004 Dec;287(6):C1657-66. doi: 10.1152/ajpcell.00172.2004. Epub 2004 Aug 4. Am J Physiol Cell Physiol. 2004. PMID: 15294853 Free article.
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S-1-P) are both low molecular weight lysophospholipid (LPL) ligands that are recognized by the Edg family of G protein-coupled receptors. ...However, pretreatment of HUVECs w
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S-1-P) are both low molecular weig
Lysophospholipid regulation of mononuclear phagocytes.
Lee H, Liao JJ, Graeler M, Huang MC, Goetzl EJ. Lee H, et al. Biochim Biophys Acta. 2002 May 23;1582(1-3):175-7. doi: 10.1016/s1388-1981(02)00153-1. Biochim Biophys Acta. 2002. PMID: 12069826 Review.
Blood monocytes and tissue macrophages derived from monocyte differentiation in tissues are central elements of innate immunity in host defense against numerous pathogens and other challenges. ...Lysophospholipids, including lysophosphatidic acid (LPA) …
Blood monocytes and tissue macrophages derived from monocyte differentiation in tissues are central elements of innate immunit …
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