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Activity and subcellular distribution of cathepsins in primary human monocytes.
Greiner A, Lautwein A, Overkleeft HS, Weber E, Driessen C. Greiner A, et al. J Leukoc Biol. 2003 Feb;73(2):235-42. doi: 10.1189/jlb.0802398. J Leukoc Biol. 2003. PMID: 12554800
We used novel chemical tools to visualize Cat in an activity-dependent manner. Primary human monocytes contained active CatS, -B, and -H, while CatL was absent. ...On a subcellular scale, the bulk of active Cat was concentrated in …
We used novel chemical tools to visualize Cat in an activity-dependent manner. Primary human monocytes contained …
MHC Class II levels and intracellular localization in human dendritic cells are regulated by calmodulin kinase II.
Herrmann TL, Agrawal RS, Connolly SF, McCaffrey RL, Schlomann J, Kusner DJ. Herrmann TL, et al. J Leukoc Biol. 2007 Sep;82(3):686-99. doi: 10.1189/jlb.0107045. Epub 2007 Jun 22. J Leukoc Biol. 2007. PMID: 17586661
Dendritic cells (DC) are professional APC, which activate the adaptive immune response. A Ca2+-calmodulin (CaM)-CaM kinase II (CaMKII) pathway regulates maturation and MHC Class II antigen presentation in human DC. The objective of this study was to characterize the …
Dendritic cells (DC) are professional APC, which activate the adaptive immune response. A Ca2+-calmodulin (CaM)-CaM kinase II (CaMKII …