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Alternative activation in systemic juvenile idiopathic arthritis monocytes.
Macaubas C, Nguyen KD, Peck A, Buckingham J, Deshpande C, Wong E, Alexander HC, Chang SY, Begovich A, Sun Y, Park JL, Pan KH, Lin R, Lih CJ, Augustine EM, Phillips C, Hadjinicolaou AV, Lee T, Mellins ED. Macaubas C, et al. Clin Immunol. 2012 Mar;142(3):362-72. doi: 10.1016/j.clim.2011.12.008. Epub 2011 Dec 28. Clin Immunol. 2012. PMID: 22281427 Free PMC article.
Systemic juvenile idiopathic arthritis (SJIA) is a chronic autoinflammatory condition. ...To characterize the activation state (classical/M1 vs. alternative/M2) of SJIA monocytes, we immunophenotyped monocytes using several
Systemic juvenile idiopathic arthritis (SJIA) is a chronic autoinflammatory condition. ...To characterize the
The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis.
Lin YT, Wang CT, Gershwin ME, Chiang BL. Lin YT, et al. Autoimmun Rev. 2011 Jun;10(8):482-9. doi: 10.1016/j.autrev.2011.02.001. Epub 2011 Feb 12. Autoimmun Rev. 2011. PMID: 21320644 Review.
Juvenile idiopathic arthritis (JIA) has had a long and difficult problem with classification. ...A loss of control of the alternative secretory pathway leading to aberrant activation of phagocytes including monocytes, macrophages and neut
Juvenile idiopathic arthritis (JIA) has had a long and difficult problem with classification. ...A loss of control of t
Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions.
Mellins ED, Macaubas C, Grom AA. Mellins ED, et al. Nat Rev Rheumatol. 2011 Jun 7;7(7):416-26. doi: 10.1038/nrrheum.2011.68. Nat Rev Rheumatol. 2011. PMID: 21647204 Free PMC article. Review.
Systemic juvenile idiopathic arthritis (sJIA) has long been recognized as unique among childhood arthritides, because of its distinctive clinical and epidemiological features, including an association with macrophage activation syndrome. ...Yet
Systemic juvenile idiopathic arthritis (sJIA) has long been recognized as unique among childhood arthritides, be
MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA.
Li D, Duan M, Feng Y, Geng L, Li X, Zhang W. Li D, et al. Mol Immunol. 2016 Sep;77:205-12. doi: 10.1016/j.molimm.2016.08.007. Epub 2016 Aug 16. Mol Immunol. 2016. PMID: 27541693
Monocytes from patients with systemic juvenile idiopathic arthritis (SJIA) have both features of classical activated M1 and alternatively activated M2 macrophages. ...Taken together, the data suggest that miR-146a serves as
Monocytes from patients with systemic juvenile idiopathic arthritis (SJIA) have both features of classica
Monocyte MicroRNA Expression in Active Systemic Juvenile Idiopathic Arthritis Implicates MicroRNA-125a-5p in Polarized Monocyte Phenotypes.
Schulert GS, Fall N, Harley JB, Shen N, Lovell DJ, Thornton S, Grom AA. Schulert GS, et al. Arthritis Rheumatol. 2016 Sep;68(9):2300-13. doi: 10.1002/art.39694. Arthritis Rheumatol. 2016. PMID: 27014994 Free PMC article.
OBJECTIVE: Systemic juvenile idiopathic arthritis (JIA) is an inflammatory disease of childhood in which cells of the monomyelocytoid lineage are thought to be key effector cells. Monocytes from patients with systemic JIA have a distinct …
OBJECTIVE: Systemic juvenile idiopathic arthritis (JIA) is an inflammatory disease of childhood in which cells o …
Phagocyte-derived S100 proteins in autoinflammation: putative role in pathogenesis and usefulness as biomarkers.
Kessel C, Holzinger D, Foell D. Kessel C, et al. Clin Immunol. 2013 Jun;147(3):229-41. doi: 10.1016/j.clim.2012.11.008. Epub 2012 Dec 7. Clin Immunol. 2013. PMID: 23269200 Review.
The cytoplasmic S100 proteins derived from cells of myeloid origin are promising new markers of (auto-)inflammation. S100A8/A9 and S100A12 are released from monocytes and granulocytes during activation of the innate immune system. Tissue and serum concentrations cor …
The cytoplasmic S100 proteins derived from cells of myeloid origin are promising new markers of (auto-)inflammation. S100A8/A9 and S100A12 a …
Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting : Toronto, Canada. 14-17 April 2016.
Fotis L, Shaikh N, Baszis K, French A, Tarr P, Grevich S, Lee P, Ringold S, Leroux B, Leahey H, Yuasa M, Foster J, Sokolove J, Lahey L, Robinson W, Newsom J, Stevens A, Karasawa R, Tamaki M, Tanaka M, Sato T, Yudoh K, Jarvis JN, Moncrieffe H, Bennett MF, Tsoras M, Luyrink L, Xu H, Prahalad S, Morris P, Dare J, Nigrovic PA, Rosenkranz M, Becker M, O’Neil KM, Griffin T, Lovell DJ, Grom AA, Medvedovic M, Thompson SD, Zhu L, Jiang K, Wong L, Buck MJ, Chen Y, Moncrieffe H, Brungs L, Liu T, Wang T, Jarvis JN, Alsaeid K, Alfailakawi J, Alenezi H, Alsaeed H, Beukelman T, Natter M, Ilowite N, Mieszkalski K, Burrell G, Best B, Bristow H, Carr S, Dennos A, Kaufmann R, Kimura Y, Schanberg L, Blier PR, Boneparth A, Wenderfer SE, Moorthy LN, Radhakrishna SM, Sagcal-Gironella ACP, von Scheven E, Gedik KC, Siddique S, Aguiar CL, Erkan D, Cohen E, Lee Y, Dossett M, Mehta D, Davis R, Gilbert M, Goilav B, Meidan E, Hsu J, Boneparth A, Chua A, Ardoin S, Wenderfer SE, Von Scheven E, Ruth NM, Hui-Yuen J, Gedik KC, Bermudez L, Cook A, Imundo L, Starr A, Eichenfield A, Askanase A, Janow G, Schanberg LE, Setoguchi S, Hasselblad V, Mellins ED, Schneider R, Kimura Y; The CARRA Legacy Registry Investigators, Kimura Y, Grevich S, Beukelman T, Morgan E, Graham TB, Ibarra M, Ruas YS, Klein-Gitelman M, Onel K, Prahalad S, Punaro M, Ringold S, Toib D, Van Mater H, Weiss JE, Weiss PF, Mieszkalski K, Schanberg LE, Kwok TSH, Bisaillon J, Smith C, Brosseau L, Stinson J, Huber AM, Duffy CM, April KT, Lewandowski LB, Scott C, Li SC, Torok KS, Rabinovich CE, Hong SD, Becker ML, Dedeoglu F, Ibarra MF, Ferguson PJ, Fuhbrigge RC, Stewart KG, Pope E, Laxer RM, Mason TG, Higgins GC, Li X, Punaro MG, Tomlinson G, Pullenayegum E, Matelski J, Schanberg L, Feldman BM, Manthiram K, Correa H, Edwards K, Oberle EJ, Bayer M, Co DO, Baris HE, Chiu Y, Huber A, Kim S, Oberle EJ, Beukelman T, Orandi AB, Baszis KW, Dharnidharka V, Hoeltzel MF; for the CARRA JDM Committee, Reed A, Huber A, Tomlinson G, Pullenayegum E, Matelski J, Goh YI, Schanberg L, Feldman BM, Schnabel A, Range U, Hahn G, Siepmann T, Berner R, Hedrich CM, Stevens B, Torok KS, Li S, Hershey N, Curran M, Higgins G, Moore K, Rabinovich E, Stevens AM; for the CARRA Registry Investigators, Stinson J, Connelly M, Huber A, Luca N, Spiegel L, Tsimicalis A, Luca S, Tajuddin N, Berard R, Barsalou J, Campillo S, Dancey P, Duffy C, Feldman B, Johnson N, McGrath P, Shiff N, Tse S, Tucker L, Victor C, Stinson J, Lalloo C, Harris L, Cafazzo J, Spiegel L, Feldman B, Luca N, Laxer R, Bullock DR, Vehe RK, Zhang L, Correll CK, Ganguli S, Shenberger M, Korumilli R, Gottlieb B, Rodriguez M, de Ranieri D, Onel K, Wagner-Weiner L, Tesher M, Wojcicki ER, Maletta KL, Co DO, Malloy M, Thomson S, Olson JC, Wenderfer SE, Gilbert M, Hsu J, Sule S, Rubinstein TB, Goilav B, Okamura DM, Chua A, Greenbaum LA, Lane JC, von Scheven E, Ardoin SP, Ruth NM, Woo JMP, Malloy MM, Jegers JA, Hahn DJ, Hintermeyer MK, Martinetti SM, Heckel GR, Roth-Wojcicki EL, Co DO. Fotis L, et al. Pediatr Rheumatol Online J. 2016 Jul 12;14 Suppl 1(Suppl 1):41. doi: 10.1186/s12969-016-0098-0. Pediatr Rheumatol Online J. 2016. PMID: 27409414 Free PMC article.
Ruth P13 Transitioning lupus patients from pediatric to adult rheumatology Joyce Hui-Yuen, Kader Cetin Gedik, Liza Bermudez, Ashlea Cook, Lisa Imundo, Amy Starr, Andrew Eichenfield, Anca Askanase P14 The systemic juvenile idiopathic arthritis cohort of …
Ruth P13 Transitioning lupus patients from pediatric to adult rheumatology Joyce Hui-Yuen, Kader Cetin Gedik, Liza Bermudez, Ashlea Cook, Li …