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Your search for Co culture Systems of Drug Treated Acute Myeloid Leukemia Cells and T Cells for In Vitro and In Vivo Study retrieved no results
Co-culture Systems of Drug-Treated Acute Myeloid Leukemia Cells and T Cells for In Vitro and In Vivo Study.
Li Y, Su R, Chen J. Li Y, et al. STAR Protoc. 2020 Sep 18;1(2):100097. doi: 10.1016/j.xpro.2020.100097. Epub 2020 Aug 28. STAR Protoc. 2020. PMID: 32995754 Free PMC article.
A combination of immunotherapy and chemotherapy strategies could strengthen antitumor effects. This protocol elucidates a robust method via co-culturing drug pre-treated acute myeloid leukemia cells with CD3(+) T cells, deri …
A combination of immunotherapy and chemotherapy strategies could strengthen antitumor effects. This protocol elucidates a robust method via …
Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition.
Dzama MM, Steiner M, Rausch J, Sasca D, Schönfeld J, Kunz K, Taubert MC, McGeehan GM, Chen CW, Mupo A, Hähnel P, Theobald M, Kindler T, Koche RP, Vassiliou GS, Armstrong SA, Kühn MWM. Dzama MM, et al. Blood. 2020 Nov 19;136(21):2442-2456. doi: 10.1182/blood.2020005037. Blood. 2020. PMID: 32589720 Free PMC article.
Primary acute myeloid leukemia (AML) cells harvested from patients with NPM1mutFLT3mut AML showed significantly better responses to combined menin and FLT3 inhibition than to single-drug or vehicle control treatment, whereas AML cells wit …
Primary acute myeloid leukemia (AML) cells harvested from patients with NPM1mutFLT3mut AML showed significantly …
Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance.
Barbier V, Erbani J, Fiveash C, Davies JM, Tay J, Tallack MR, Lowe J, Magnani JL, Pattabiraman DR, Perkins AC, Lisle J, Rasko JEJ, Levesque JP, Winkler IG. Barbier V, et al. Nat Commun. 2020 Apr 27;11(1):2042. doi: 10.1038/s41467-020-15817-5. Nat Commun. 2020. PMID: 32341362 Free PMC article.
The endothelial cell adhesion molecule E-selectin is a key component of the bone marrow hematopoietic stem cell (HSC) vascular niche regulating balance between HSC self-renewal and commitment. We now report in contrast, E-selectin directly triggers signaling pathway …
The endothelial cell adhesion molecule E-selectin is a key component of the bone marrow hematopoietic stem cell (HSC) vascular …
Three-dimensional ex vivo co-culture models of the leukaemic bone marrow niche for functional drug testing.
Dhami SPS, Kappala SS, Thompson A, Szegezdi E. Dhami SPS, et al. Drug Discov Today. 2016 Sep;21(9):1464-1471. doi: 10.1016/j.drudis.2016.04.019. Epub 2016 Apr 27. Drug Discov Today. 2016. PMID: 27130156 Review.
Acute myeloid leukaemia (AML) is a hierarchically structured malignancy in which aberrant leukemic stem cells drive the production of leukaemic blast cell clones. ...Classical AML cell cultures fail to mimic the BMM and, therefore, drug d
Acute myeloid leukaemia (AML) is a hierarchically structured malignancy in which aberrant leukemic stem cells drive the
Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells.
Chen F, Ishikawa Y, Akashi A, Naoe T, Kiyoi H. Chen F, et al. Oncotarget. 2016 Jul 26;7(30):47018-47032. doi: 10.18632/oncotarget.10147. Oncotarget. 2016. PMID: 27331411 Free PMC article.
FLT3 mutation is found in about 30% of acute myeloid leukemia (AML) patients and is associated with a poor prognosis. ...We demonstrated that FL-stimulation much more strongly reduced growth inhibitory effects of FLT3 inhibitors on Wt- and mutant-FLT3 co
FLT3 mutation is found in about 30% of acute myeloid leukemia (AML) patients and is associated with a poor prognosis. . …
Abstracts of Presentations at the Association of Clinical Scientists 143rd Meeting Louisville, KY May 11-14,2022.
[No authors listed] [No authors listed] Ann Clin Lab Sci. 2022 May;52(3):511-525. Ann Clin Lab Sci. 2022. PMID: 35777803
We filed an investigational new drug (IND) application, and received study may proceed authorization from the FDA. ...We used mass cytometry by time-of-flight (CyTOF), flow cytometry, and T cell receptor immunosequencing to conduct simultaneous single-cell
We filed an investigational new drug (IND) application, and received study may proceed authorization from the FDA. ...We used …