Considerations regarding use of solvents in in vitro cell based assays.
Cytotechnology. 2013.
PMID: 23328992
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Considerations regarding use of solvents in in vitro cell based assays.
Cytotechnology. 2013 Oct;65(5):887-94. doi: 10.1007/s10616-012-9530-6. Epub 2013 Jan 18.
Cytotechnology. 2013.
PMID: 23328992
Free PMC article.
Cell culture systems are widely used for the investigation of in vitro immunomodulatory effects of medicines and natural products. ...Furthermore, these results show the importance of keeping solvent concentrations constant in serial dilution of any co …
Cell culture systems are widely used for the investigation of in vitro immunomodulatory effects of medicines and natura …
In Vitro and In Vivo Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin.
Mol Pharm. 2021 Mar 1;18(3):1247-1263. doi: 10.1021/acs.molpharmaceut.0c01114. Epub 2021 Jan 19.
Mol Pharm. 2021.
PMID: 33464911
Free PMC article.
In vitro analyses revealed that the curcumin-loaded mPEG(5kDa)-b-p(HPMA-Bz)(17.1kDa) micelles were internalized by different types of cancer cells, resulting in curcumin-induced cell death. ...The faster clearance of curcumin in vivo compared to in …
In vitro analyses revealed that the curcumin-loaded mPEG(5kDa)-b-p(HPMA-Bz)(17.1kDa) micelles were internalized by different t …
Synthesis, in vitro cytotoxic activity and molecular docking study of androstene and estrone derivatives.
Steroids. 2023 Sep;197:109259. doi: 10.1016/j.steroids.2023.109259. Epub 2023 Jun 17.
Steroids. 2023.
PMID: 37336339
Subsequently, the 16-arylidene estrone reacted with acid chloride in presence of quaternary amine in halogenated solvent resulting in the steroidal arylidene derivatives. Synthesis, Characterization and in vitro cytotoxic activity of arylidenes are rationaliz …
Subsequently, the 16-arylidene estrone reacted with acid chloride in presence of quaternary amine in halogenated solvent resulting in …
Therapeutic potential of toleragens in the management of antiphospholipid syndrome.
BioDrugs. 2004;18(5):297-305. doi: 10.2165/00063030-200418050-00002.
BioDrugs. 2004.
PMID: 15377172
Review.
The relation between autoantibodies and the pathophysiology of APS is not clearly understood, but numerous in vitro studies have characterized the effects of antiphospholipid autoantibodies on various components of the coagulation cascade, including tissue factor an …
The relation between autoantibodies and the pathophysiology of APS is not clearly understood, but numerous in vitro studies ha …
In vitro and in vivo antileishmanial activity of the hanging sedge flavonoids based on bio- guided fractionation assay.
Chem Biol Drug Des. 2023 Jun;101(6):1425-1434. doi: 10.1111/cbdd.14226. Epub 2023 Mar 26.
Chem Biol Drug Des. 2023.
PMID: 36892494
Natural products also should be regarded as one of the most valuable applications for CL infection drug development. In this study, we assessed the in vitro and in vivo antileishmanial potential of Carex pendula Huds. (hanging sedge) methanolic extract and its fract …
Natural products also should be regarded as one of the most valuable applications for CL infection drug development. In this study, we asses …
Arginine tagged liposomal carrier for the delivery of celastrol for ferroptosis-induced hepatocellular carcinoma therapy.
Colloids Surf B Biointerfaces. 2025 Jun;250:114546. doi: 10.1016/j.colsurfb.2025.114546. Epub 2025 Feb 3.
Colloids Surf B Biointerfaces. 2025.
PMID: 39919344
Cel was encapsulated in polyethylene glycol-based liposomes modified with L-arginine (Cel@Lip-Arg). Cel@Lip-Arg has a uniform size distribution (100 nm), high drug loading (80 %), and excellent ability to target liver cancer cells. In vitro experiments …
Cel was encapsulated in polyethylene glycol-based liposomes modified with L-arginine (Cel@Lip-Arg). Cel@Lip-Arg has a uniform size di …
Polycaprolactone/gelatin-based scaffolds with tailored performance: in vitro and in vivo validation.
Mater Sci Eng C Mater Biol Appl. 2020 Feb;107:110296. doi: 10.1016/j.msec.2019.110296. Epub 2019 Oct 14.
Mater Sci Eng C Mater Biol Appl. 2020.
PMID: 31761169
During in vitro biocompatibility tests, higher cell adhesion and proliferation were found for the 60/40, 50/50 and 40/60 PCL/Ge compositions that was corroborated by MTT assay, fluorescence and microscopy. A weakened structure, more labile to the in …
During in vitro biocompatibility tests, higher cell adhesion and proliferation were found for the 60/40, 50/50 and 40/6 …
In vitro anti-leukemic assessment and sustained release behaviour of cytarabine loaded biodegradable polymer based nanoparticles.
Life Sci. 2021 Feb 15;267:118971. doi: 10.1016/j.lfs.2020.118971. Epub 2020 Dec 29.
Life Sci. 2021.
PMID: 33385406
AIMS: The study aimed to develop, characterize, and evaluate poly (e-caprolactone) (PCL) based nanoparticles for the sustained release behaviour of cytarabine and to investigate the in vitro anti-cancer influence on KG-1 leukemic cell line. ...X-ray di …
AIMS: The study aimed to develop, characterize, and evaluate poly (e-caprolactone) (PCL) based nanoparticles for the sustained releas …
In vitro dissolution/permeation tools for amorphous solid dispersions bioavailability forecasting I: Experimental design for PermeaLoop.
Eur J Pharm Sci. 2023 Sep 1;188:106512. doi: 10.1016/j.ejps.2023.106512. Epub 2023 Jul 8.
Eur J Pharm Sci. 2023.
PMID: 37423576
Free article.
To this end, this study comprises theoretical considerations on the design and experimental work towards the establishment and optimization of a PermeaLoop based dissolution/permeation assay to simultaneously evaluate the drug release and permeation using Itr …
To this end, this study comprises theoretical considerations on the design and experimental work towards the establishment and optimi …
In-vitro Evaluation of Wild Bitter Melon (Momordica charantia) Extracts against Periodontopathic Bacteria (Prevotella intermedia and Porphyromonas gingivalis) using Antibacterial, Anti-Inflammatory and Molecular Docking Analysis.
J Pharm Bioallied Sci. 2024 Apr;16(Suppl 2):S1554-S1564. doi: 10.4103/jpbs.jpbs_512_23. Epub 2024 Apr 16.
J Pharm Bioallied Sci. 2024.
PMID: 38882883
Free PMC article.
Wild bitter melon (Momordica charantia) extracts were prepared and their antibacterial and anti-biofilm assay were investigated against two different periodontopathic bacteria (Prevotella intermedia and Porphyromonas gingivalis) for the first time to the best of our knowle …
Wild bitter melon (Momordica charantia) extracts were prepared and their antibacterial and anti-biofilm assay were investigated again …
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