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Year Number of Results
1981 1
1985 1
1994 2
1995 2
1996 2
1999 1
2000 1
2001 2
2002 7
2003 6
2005 3
2006 3
2008 3
2009 2
2010 4
2011 4
2012 6
2013 1
2014 8
2015 5
2016 2
2017 9
2018 4
2019 4
2020 5
2021 7
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89 results

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Page 1
Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon.
Han S, Zhuang H, Lee PY, Li M, Yang L, Nigrovic PA, Reeves WH. Han S, et al. Arthritis Rheumatol. 2020 Jan;72(1):100-113. doi: 10.1002/art.41072. Epub 2019 Dec 10. Arthritis Rheumatol. 2020. PMID: 31390156 Free PMC article.

Ifnar1 messenger RNA and IFNAR surface staining were higher in classic monocyte/macrophages versus nonclassic monocyte/macrophages (P < 0.0001 and P < 0.05, respectively, by Student's t-test). ...Humans exhibited a similar pattern: higher

…
Ifnar1 messenger RNA and IFNAR surface staining were higher in classic monocyte/macrophages versus nonclassic monocyte/ …
The impact of interferon-regulatory factors to macrophage differentiation and polarization into M1 and M2.
Chistiakov DA, Myasoedova VA, Revin VV, Orekhov AN, Bobryshev YV. Chistiakov DA, et al. Immunobiology. 2018 Jan;223(1):101-111. doi: 10.1016/j.imbio.2017.10.005. Epub 2017 Oct 5. Immunobiology. 2018. PMID: 29032836 Review.
Exposure of monocytes to inflammatory or anti-inflammatory conditions also induces predominant differentiation to proinflammatory (M1) or anti-inflammatory (M2) macrophage subsets and phenotype switch between macrophage subsets. The pheno …
Exposure of monocytes to inflammatory or anti-inflammatory conditions also induces predominant differentiation to proinflammat …
Phenotype, function, and differentiation potential of human monocyte subsets.
Boyette LB, Macedo C, Hadi K, Elinoff BD, Walters JT, Ramaswami B, Chalasani G, Taboas JM, Lakkis FG, Metes DM. Boyette LB, et al. PLoS One. 2017 Apr 26;12(4):e0176460. doi: 10.1371/journal.pone.0176460. eCollection 2017. PLoS One. 2017. PMID: 28445506 Free PMC article.
After incubation with IL-3 and Flt3 ligand, no subset differentiated to plasmacytoid DC. After incubation with GM-CSF (M1 induction) or macrophage colony-stimulating factor (M-CSF) (M2 induction), all subsets acquired macrophage morphology, secr …
After incubation with IL-3 and Flt3 ligand, no subset differentiated to plasmacytoid DC. After incubation with GM-CSF (M1 indu …
Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome.
Tkach M, Thalmensi J, Timperi E, Gueguen P, Névo N, Grisard E, Sirven P, Cocozza F, Gouronnec A, Martin-Jaular L, Jouve M, Delisle F, Manel N, Rookhuizen DC, Guerin CL, Soumelis V, Romano E, Segura E, Théry C. Tkach M, et al. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2107394119. doi: 10.1073/pnas.2107394119. Epub 2022 Apr 19. Proc Natl Acad Sci U S A. 2022. PMID: 35439048 Free PMC article.
Tumor associated macrophages (TAMs), which differentiate from circulating monocytes, are pervasive across human cancers and comprise heterogeneous populations. ...Here, we show that triple negative breast cancer cells (TNBCs) release EVs and soluble molecules …
Tumor associated macrophages (TAMs), which differentiate from circulating monocytes, are pervasive across human cancers …
Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics.
Kotliar D, Lin AE, Logue J, Hughes TK, Khoury NM, Raju SS, Wadsworth MH 2nd, Chen H, Kurtz JR, Dighero-Kemp B, Bjornson ZB, Mukherjee N, Sellers BA, Tran N, Bauer MR, Adams GC, Adams R, Rinn JL, Melé M, Schaffner SF, Nolan GP, Barnes KG, Hensley LE, McIlwain DR, Shalek AK, Sabeti PC, Bennett RS. Kotliar D, et al. Cell. 2020 Nov 25;183(5):1383-1401.e19. doi: 10.1016/j.cell.2020.10.002. Epub 2020 Nov 6. Cell. 2020. PMID: 33159858 Free PMC article.
Ebola virus (EBOV) causes epidemics with high mortality yet remains understudied due to the challenge of experimentation in high-containment and outbreak settings. Here, we used single-cell transcriptomics and CyTOF-based single-cell protein quantification to charac …
Ebola virus (EBOV) causes epidemics with high mortality yet remains understudied due to the challenge of experimentation in high-containment …
Novel Circulating and Tissue Monocytes as Well as Macrophages in Pancreatitis and Recovery.
Manohar M, Jones EK, Rubin SJS, Subrahmanyam PB, Swaminathan G, Mikhail D, Bai L, Singh G, Wei Y, Sharma V, Siebert JC, Maecker HT, Husain SZ, Park WG, Pandol SJ, Habtezion A. Manohar M, et al. Gastroenterology. 2021 Dec;161(6):2014-2029.e14. doi: 10.1053/j.gastro.2021.08.033. Epub 2021 Aug 25. Gastroenterology. 2021. PMID: 34450180 Free PMC article.
Deep profiling uncovered heterogeneity among pancreatic and blood monocytes and identified 7 novel subsets during AP and recovery, and 6 monocyte subsets during SAP. ...CONCLUSIONS: We identified several novel monocyte/macrophage subse …
Deep profiling uncovered heterogeneity among pancreatic and blood monocytes and identified 7 novel subsets during AP and recov …
The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing.
Xu G, Qi F, Li H, Yang Q, Wang H, Wang X, Liu X, Zhao J, Liao X, Liu Y, Liu L, Zhang S, Zhang Z. Xu G, et al. Cell Discov. 2020 Oct 20;6:73. doi: 10.1038/s41421-020-00225-2. eCollection 2020. Cell Discov. 2020. PMID: 33101705 Free PMC article.
Those MDSC-like monocytes were immune-paralyzed. In contrast, monocyte-macrophages in BALFs of COVID-19 patients produced massive amounts of cytokines and chemokines, but secreted little interferons. The frequencies of peripheral T cells and NK cells w …
Those MDSC-like monocytes were immune-paralyzed. In contrast, monocyte-macrophages in BALFs of COVID-19 patients produc …
THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro.
Shiratori H, Feinweber C, Luckhardt S, Linke B, Resch E, Geisslinger G, Weigert A, Parnham MJ. Shiratori H, et al. Mol Immunol. 2017 Aug;88:58-68. doi: 10.1016/j.molimm.2017.05.027. Epub 2017 Jun 7. Mol Immunol. 2017. PMID: 28600970
Macrophages (Mphi) undergo activation to pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes in response to pathophysiologic stimuli and dysregulation of the M1-M2 balance is often associated with diseases. ...Cellular morphology, the expression profiles of 1 …
Macrophages (Mphi) undergo activation to pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes in response to pathophysio …
A Monocyte-Orchestrated IFN-I-to-IL-4 Cytokine Axis Instigates Protumoral Macrophages and Thwarts Poly(I:C) Therapy.
Guo P, Yang L, Zhang M, Zhang Y, Tong Y, Cao Y, Liu J. Guo P, et al. J Immunol. 2021 Jul 15;207(2):408-420. doi: 10.4049/jimmunol.2001411. Epub 2021 Jun 30. J Immunol. 2021. PMID: 34193600
Indeed, our recent work showed that systemic poly(I:C)/IFN treatment can undesirably trigger high arginase (ARG1) expression within the tumor-associated monocyte/macrophage compartment. Using a line of CRISPR-generated Arg1-YFP reporter knock-in mice, we have determ …
Indeed, our recent work showed that systemic poly(I:C)/IFN treatment can undesirably trigger high arginase (ARG1) expression within the tumo …
Differential roles of lung dendritic cell subsets against respiratory virus infection.
Kim TH, Lee HK. Kim TH, et al. Immune Netw. 2014 Jun;14(3):128-37. doi: 10.4110/in.2014.14.3.128. Epub 2014 Jun 19. Immune Netw. 2014. PMID: 24999309 Free PMC article. Review.
Moreover, pDCs have been reported to promote an antiviral response by inducing type I interferon production rather than adaptive immunity. ...Under certain viral infection, contextually controlling the balance of these specialized DC subsets is important for …
Moreover, pDCs have been reported to promote an antiviral response by inducing type I interferon production rather than adapti …
89 results