A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.
Bahr C, von Paleske L, Uslu VV, Remeseiro S, Takayama N, Ng SW, Murison A, Langenfeld K, Petretich M, Scognamiglio R, Zeisberger P, Benk AS, Amit I, Zandstra PW, Lupien M, Dick JE, Trumpp A, Spitz F.
Bahr C, et al.
Nature. 2018 Jan 25;553(7689):515-520. doi: 10.1038/nature25193. Epub 2018 Jan 17.
Nature. 2018.
PMID: 29342133
Here we show that an evolutionarily conserved region located 1.7 megabases downstream of the Myc gene that has previously been labelled as a 'super-enhancer' is essential for the regulation of Myc expression levels in both normal haematopoietic …
Here we show that an evolutionarily conserved region located 1.7 megabases downstream of the Myc gene that has previously been …