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Downregulation of tumor necrosis factor expression in the human Mono-Mac-6 cell line by lipopolysaccharide.
Haas JG, Thiel C, Blömer K, Weiss EH, Riethmüller G, Ziegler-Heitbrock HW. Haas JG, et al. J Leukoc Biol. 1989 Jul;46(1):11-4. doi: 10.1002/jlb.46.1.11. J Leukoc Biol. 1989. PMID: 2732625
Mono-Mac-6 cells, but not U937 cells, can be induced to rapidly express tumor necrosis factor (TNF) mRNA and protein when triggered with lipopolysaccharide (LPS) at 1 microgram/ml. ...While these results show that only strin
Mono-Mac-6 cells, but not U937 cells, can be induced to rapidly express tumor necrosis factor
Distinct patterns of differentiation induced in the monocytic cell line Mono Mac 6.
Ziegler-Heitbrock HW, Schraut W, Wendelgass P, Ströbel M, Sternsdorf T, Weber C, Aepfelbacher M, Ehlers M, Schütt C, Haas JG. Ziegler-Heitbrock HW, et al. J Leukoc Biol. 1994 Jan;55(1):73-80. doi: 10.1002/jlb.55.1.73. J Leukoc Biol. 1994. PMID: 8283142
The human Mono Mac 6 cell line exhibits many characteristics of mature blood monocytes including expression of the CD14 molecule and production of cytokines, such as interleukin-1 (IL-1), IL-6, and tumor necrosis
The human Mono Mac 6 cell line exhibits many characteristics of mature blood monocytes including …
IL-4 inhibits the LPS-induced expression of CD14 and monocyte-specific esterase mRNA in MONO-MAC-6 cells.
Quentmeier H, Kolsdorf K, Zaborski M, Drexler HG. Quentmeier H, et al. Leukemia. 1994 Sep;8(9):1551-6. Leukemia. 1994. PMID: 7522293
The human MONO-MAC-6 cell line expresses the monocyte-associated differentiation markers CD14 and monocyte-specific esterase (MSE) and can be stimulated by lipopolysaccharide (LPS) to produce high mRNA levels of monocyte-rel …
The human MONO-MAC-6 cell line expresses the monocyte-associated differentiation markers CD …
Molecular mechanisms in down-regulation of tumor necrosis factor expression.
Haas JG, Baeuerle PA, Riethmüller G, Ziegler-Heitbrock HW. Haas JG, et al. Proc Natl Acad Sci U S A. 1990 Dec;87(24):9563-7. doi: 10.1073/pnas.87.24.9563. Proc Natl Acad Sci U S A. 1990. PMID: 2263611 Free PMC article.
Excessive production of tumor necrosis factor (TNF) after stimulation by lipopolysaccharide (LPS) may result in fever, intravascular coagulation, and lethal shock. ...We have analyzed the molecular mechanisms involved in the induction of desensitizatio …
Excessive production of tumor necrosis factor (TNF) after stimulation by lipopolysaccharide (LPS) may result in …
Tolerance to lipopolysaccharide involves mobilization of nuclear factor kappa B with predominance of p50 homodimers.
Ziegler-Heitbrock HW, Wedel A, Schraut W, Ströbel M, Wendelgass P, Sternsdorf T, Bäuerle PA, Haas JG, Riethmüller G. Ziegler-Heitbrock HW, et al. J Biol Chem. 1994 Jun 24;269(25):17001-4. J Biol Chem. 1994. PMID: 7516328
Stimulation of the human monocytic cell line Mono Mac 6 with lipopolysaccharide (LPS) leads to rapid and transient expression of cytokines like tumor necrosis factor (TNF). ...Similar to Mono M
Stimulation of the human monocytic cell line Mono Mac 6 with lipopolysaccharide (LPS) leads …
In vitro desensitization to lipopolysaccharide suppresses tumour necrosis factor, interleukin-1 and interleukin-6 gene expression in a similar fashion.
Ziegler-Heitbrock HW, Blumenstein M, Käfferlein E, Kieper D, Petersmann I, Endres S, Flegel WA, Northoff H, Riethmüller G, Haas JG. Ziegler-Heitbrock HW, et al. Immunology. 1992 Feb;75(2):264-8. Immunology. 1992. PMID: 1551689 Free PMC article.
Like blood monocytes, the human monocytic cell line Mono Mac 6 can be stimulated by lipopolysaccharide (LPS) at 1 microgram/ml to produce high levels of cytokines. When Mono Mac 6 cells are stimulated for 4- …
Like blood monocytes, the human monocytic cell line Mono Mac 6 can be stimulated by lipopolysac
Inhibition of lipopolysaccharide-induced in vitro desensitization by interferon-gamma.
Haas JG, Meyer N, Riethmüller G, Ziegler-Heitbrock HW. Haas JG, et al. Eur J Immunol. 1990 May;20(5):1181-4. doi: 10.1002/eji.1830200535. Eur J Immunol. 1990. PMID: 2113478
Exposure of Mono-Mac-6 cells to lipopolysaccharide (LPS) can induce rapid and transient expression of cytokines like tumor necrosis factor (TNF), interleukin 1 and interleukin 6. ...Addition of interferon-gamma (IFN-g …
Exposure of Mono-Mac-6 cells to lipopolysaccharide (LPS) can induce rapid and transient expression of cyt …
Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production.
Bonder CS, Dickensheets HL, Finlay-Jones JJ, Donnelly RP, Hart PH. Bonder CS, et al. J Immunol. 1998 Apr 15;160(8):4048-56. J Immunol. 1998. PMID: 9558115 Free article.
IL-4 also suppressed IL-1beta but not TNF-alpha production by Mono Mac 6 cells, which express minimal levels of gammac. For gammac-expressing LPS/PMA-activated U937 cells, IL-4 decreased both TNF-alpha and IL-1beta production. ...
IL-4 also suppressed IL-1beta but not TNF-alpha production by Mono Mac 6 cells, which express minimal lev …
Reverse signaling through transmembrane TNF confers resistance to lipopolysaccharide in human monocytes and macrophages.
Eissner G, Kirchner S, Lindner H, Kolch W, Janosch P, Grell M, Scheurich P, Andreesen R, Holler E. Eissner G, et al. J Immunol. 2000 Jun 15;164(12):6193-8. doi: 10.4049/jimmunol.164.12.6193. J Immunol. 2000. PMID: 10843670 Free article.
Apoptosis is mediated by two routes, first via transmembrane TNF-alpha (mTNF) expressed on PBMC and, in addition, by TNF-independent soluble factors that trigger apoptosis in EC. ...Peripheral blood MO, MO-derived macrophages (MPhi), or the monocytic cell
Apoptosis is mediated by two routes, first via transmembrane TNF-alpha (mTNF) expressed on PBMC and, in addition, by TNF-indep …
Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15.
Musso T, Calosso L, Zucca M, Millesimo M, Ravarino D, Giovarelli M, Malavasi F, Ponzi AN, Paus R, Bulfone-Paus S. Musso T, et al. Blood. 1999 May 15;93(10):3531-9. Blood. 1999. PMID: 10233906
We demonstrate here that biologically active IL-15 is indeed detectable in a constitutively expressed, membrane-bound form on normal human monocytes, as well as on monocytic cell lines (MONO-MAC-6, THP-1, and U937), but not on human
We demonstrate here that biologically active IL-15 is indeed detectable in a constitutively expressed, membrane-bound form on normal …
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