Therapeutic delivery of CCL2 modulates immune response and restores host-microbe homeostasis.
Shehabeldin M, Gao J, Cho Y, Chong R, Tabib T, Li L, Smardz M, Gaffen SL, Diaz PI, Lafyatis R, Little SR, Sfeir C.
Shehabeldin M, et al.
Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2400528121. doi: 10.1073/pnas.2400528121. Epub 2024 Aug 26.
Proc Natl Acad Sci U S A. 2024.
PMID: 39186644
Many chronic inflammatory diseases are attributed to disturbances in host-microbe interactions, which drive immune-mediated tissue damage. ...Furthermore, single-cell ribonucleic acid (RNA) sequencing indicated that CCL2 therapy reversed disease-associated transcriptomic p …
Many chronic inflammatory diseases are attributed to disturbances in host-microbe interactions, which drive immune-mediated tissue da …