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Trem1 Induces Periodontal Inflammation via Regulating M1 Polarization.
Wu D, Weng Y, Feng Y, Liang B, Wang H, Li L, Wang Z. Wu D, et al. J Dent Res. 2022 Apr;101(4):437-447. doi: 10.1177/00220345211044681. Epub 2021 Nov 1. J Dent Res. 2022. PMID: 34719965
Periodontitis is a chronic inflammatory condition characterized by destruction of nonmineralized and mineralized connective tissues. This study evaluated the role of Trem1 (triggering receptors expressed on myeloid cells 1) in periodontitis by i …
Periodontitis is a chronic inflammatory condition characterized by destruction of nonmineralized and mineralized connective tissues. This st …
Increased expression of triggering receptor expressed on myeloid cells 1 and 2 in inflamed human gingiva.
Chen SS, Wang K, Zhao J, Wu WC, Wu YF, Zhao L. Chen SS, et al. J Periodontal Res. 2017 Jun;52(3):512-521. doi: 10.1111/jre.12417. Epub 2016 Sep 14. J Periodontal Res. 2017. PMID: 27624412
This study is the first to identify TREM-2 in periodontal tissue, as well as the protein expression changes of TREM-1 and TREM-2 in periodontal tissues. ...RESULTS: In addition to myeloid cells in gingival connective tissues, TREM-1
This study is the first to identify TREM-2 in periodontal tissue, as well as the protein expression changes of TREM-1 a …
Expression and regulation of triggering receptor expressed on myeloid cells 1 in periodontal diseases.
Willi M, Belibasakis GN, Bostanci N. Willi M, et al. Clin Exp Immunol. 2014 Oct;178(1):190-200. doi: 10.1111/cei.12397. Clin Exp Immunol. 2014. PMID: 24924298 Free PMC article.
'red complex' bacteria) are characteristic subgingival biofilm species. The triggering receptor expressed on myeloid cells 1 (TREM-1) is a cell surface receptor of the immunoglobulin superfamily, with a role in the amplifica …
'red complex' bacteria) are characteristic subgingival biofilm species. The triggering receptor expressed on myeloid
[Expression of triggering receptors expressed by myeloid cells-1 in macrophages stimulated by Porphyromonas gingivalis-lipopolysaccharide].
Yang Y, Chen SS, Xu CM, Wu YF, Zhao L. Yang Y, et al. Hua Xi Kou Qiang Yi Xue Za Zhi. 2018 Oct 1;36(5):475-481. doi: 10.7518/hxkq.2018.05.003. Hua Xi Kou Qiang Yi Xue Za Zhi. 2018. PMID: 30465338 Free PMC article. Chinese.
OBJECTIVE: Soluble triggering receptors expressed by myeloid cells-1 (sTREM-1) and inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) in macrophage cells were stimulated by Porphyromonas gingivalis-lipopolysaccharide (Pg …
OBJECTIVE: Soluble triggering receptors expressed by myeloid cells-1 (sTREM-1) and inflammatory cy …
Regulation of PGLYRP1 and TREM-1 during Progression and Resolution of Gingival Inflammation.
Silbereisen A, Hallak AK, Nascimento GG, Sorsa T, Belibasakis GN, Lopez R, Bostanci N. Silbereisen A, et al. JDR Clin Trans Res. 2019 Oct;4(4):352-359. doi: 10.1177/2380084419844937. Epub 2019 Apr 23. JDR Clin Trans Res. 2019. PMID: 31013451
INTRODUCTION: The triggering receptor expressed on myeloid cells 1 (TREM-1) signaling pathway is stimulated by bacteria and, together with its putative ligand peptidoglycan recognition protein 1 (PGLYRP1), propagates proinfl …
INTRODUCTION: The triggering receptor expressed on myeloid cells 1 (TREM-1) signaling pathw …
Regulation of Salivary Peptidoglycan Recognition Protein 1 in Adolescents.
Raivisto T, Heikkinen AM, Silbereisen A, Kovanen L, Ruokonen H, Tervahartiala T, Haukka J, Sorsa T, Bostanci N. Raivisto T, et al. JDR Clin Trans Res. 2020 Oct;5(4):332-341. doi: 10.1177/2380084419894287. Epub 2019 Dec 20. JDR Clin Trans Res. 2020. PMID: 31860804
Recently, PGLYRP1 was identified as a ligand for triggering receptor expressed on myeloid cells 1 (TREM-1). Although PGLYRP1 is involved in immune and inflammatory responses, its levels in initial stages of periodontal disea …
Recently, PGLYRP1 was identified as a ligand for triggering receptor expressed on myeloid cells 1
Increased gingival crevicular fluid levels of soluble triggering receptor expressed on myeloid cells (sTREM) -1 in severe periodontitis.
Bisson C, Massin F, Lefevre PA, Thilly N, Miller N, Gibot S. Bisson C, et al. J Clin Periodontol. 2012 Dec;39(12):1141-8. doi: 10.1111/jcpe.12008. Epub 2012 Oct 16. J Clin Periodontol. 2012. PMID: 23067264
AIM: This study was designed to evaluate the presence of a new regulator of innate immunity in periodontitis: the soluble form of triggering receptor on myeloid cells-1 (sTREM-1) in gingival crevicular fluid (GCF). ...In multivaria …
AIM: This study was designed to evaluate the presence of a new regulator of innate immunity in periodontitis: the soluble form of …
TREM-1 Is Upregulated in Experimental Periodontitis, and Its Blockade Inhibits IL-17A and RANKL Expression and Suppresses Bone loss.
Bostanci N, Abe T, Belibasakis GN, Hajishengallis G. Bostanci N, et al. J Clin Med. 2019 Oct 1;8(10):1579. doi: 10.3390/jcm8101579. J Clin Med. 2019. PMID: 31581596 Free PMC article.
AIM: Triggering receptor expressed on myeloid cells-1 (TREM-1) is a modifier of local and systemic inflammation. ...CONCLUSION: Our findings show for the first time that TREM-1 regulates the IL-17A-RANKL/OPG axis and …
AIM: Triggering receptor expressed on myeloid cells-1 (TREM-1) is a modifier of local and s …