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1992 1
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2013 2
2014 1
2015 3
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2018 3
2019 7
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Expression of Dopamine Receptors in Immune Regulatory Cells.
Arce-Sillas A, Sevilla-Reyes E, Álvarez-Luquín DD, Guevara-Salinas A, Boll MC, Pérez-Correa CA, Vivas-Almazan AV, Rodríguez-Ortiz U, Castellanos Barba C, Hernandez M, Fragoso G, Sciutto E, Cárdenas G, Adalid-Peralta LV. Arce-Sillas A, et al. Neuroimmunomodulation. 2019;26(3):159-166. doi: 10.1159/000501187. Epub 2019 Jul 16. Neuroimmunomodulation. 2019. PMID: 31311029
While only regulatory T cells (Tregs) have been proved to express dopamine receptors, it is not known whether other regulatory cells such as CD8regs, regulatory B cells (Bregs), tolerogenic dendritic cells, and …
While only regulatory T cells (Tregs) have been proved to express dopamine receptors, it is not known whe …
Molecular design of hypothalamus development.
Romanov RA, Tretiakov EO, Kastriti ME, Zupancic M, Häring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews WD, Parnavelas JG, Farlik M, Bock C, Adameyko I, Hökfelt T, Keimpema E, Harkany T. Romanov RA, et al. Nature. 2020 Jun;582(7811):246-252. doi: 10.1038/s41586-020-2266-0. Epub 2020 May 6. Nature. 2020. PMID: 32499648 Free PMC article.
Nevertheless, we lack a developmental blueprint that integrates the molecular determinants of neuronal and glial diversity along temporal and spatial scales of hypothalamus development(3). Here we combine single-cell RNA sequencing of 51,199 mouse cells of ectoderma …
Nevertheless, we lack a developmental blueprint that integrates the molecular determinants of neuronal and glial diversity along temporal an …
Distorted expression of dopamine receptor genes in systemic lupus erythematosus.
Jafari M, Ahangari G, Saberi M, Samangoui S, Torabi R, Zouali M. Jafari M, et al. Immunobiology. 2013 Jul;218(7):979-83. doi: 10.1016/j.imbio.2012.11.002. Epub 2012 Nov 21. Immunobiology. 2013. PMID: 23266246
We found that all receptors are expressed in lupus peripheral blood cells. We also discovered that dopamine receptor 2 gene (DR2) was underexpressed, and that DR4 was overexpressed in lupus patients, as compared to controls. Cell sorting …
We found that all receptors are expressed in lupus peripheral blood cells. We also discovered that dopamine rece …
Targeting the Dopaminergic System in Autoimmunity.
Vidal PM, Pacheco R. Vidal PM, et al. J Neuroimmune Pharmacol. 2020 Mar;15(1):57-73. doi: 10.1007/s11481-019-09834-5. Epub 2019 Jan 19. J Neuroimmune Pharmacol. 2020. PMID: 30661214 Review.
Dopamine receptors are broadly expressed on different immune cells with multifunctional effects depending on the dopamine concentration available and the pattern of expression of five dopamine receptors displaying dif
Dopamine receptors are broadly expressed on different immune cells with multifunctional effects depending
Fresh Evidence for Platelets as Neuronal and Innate Immune Cells: Their Role in the Activation, Differentiation, and Deactivation of Th1, Th17, and Tregs during Tissue Inflammation.
Ponomarev ED. Ponomarev ED. Front Immunol. 2018 Mar 2;9:406. doi: 10.3389/fimmu.2018.00406. eCollection 2018. Front Immunol. 2018. PMID: 29599771 Free PMC article. Review.
In addition, activated platelets synthesize a number of lipid pro-inflammatory mediators such as platelet-activating factor and prostaglandins/thromboxanes. Notably, platelets express multiple toll-like receptors and MHC class I on their surface and store IgG in the …
In addition, activated platelets synthesize a number of lipid pro-inflammatory mediators such as platelet-activating factor and prostaglandi …
Novel Insight into Differential Gene Expression and Clinical Significance of Dopamine Receptors, COMT, and IL6 in BPH and Prostate Cancer.
Akbarian F, Abolhasani M, Dadkhah F, Asadi F, Ahangari G. Akbarian F, et al. Curr Mol Med. 2019;19(8):605-619. doi: 10.2174/1566524019666190709180146. Curr Mol Med. 2019. PMID: 31288722
OBJECTIVE: The aim of this study was to evaluate the gene expression of dopamine receptor family, COMT, and IL6 to identify novel correlations in BPH and PCa in both blood and tumor of the patients. ...CONCLUSION: Results implicate a potential cross- talk bet …
OBJECTIVE: The aim of this study was to evaluate the gene expression of dopamine receptor family, COMT, and IL6 to iden …
Dopamine and T cells: dopamine receptors and potent effects on T cells, dopamine production in T cells, and abnormalities in the dopaminergic system in T cells in autoimmune, neurological and psychiatric diseases.
Levite M. Levite M. Acta Physiol (Oxf). 2016 Jan;216(1):42-89. doi: 10.1111/apha.12476. Epub 2015 Sep 24. Acta Physiol (Oxf). 2016. PMID: 25728499 Review.
The review covers the following findings: (i) T cells express functional dopamine receptors (DRs) D1R-D5R, but their level and function are dynamic and context-sensitive, (ii) DR membranal protein levels do not necessarily correlate with DR mRNA levels …
The review covers the following findings: (i) T cells express functional dopamine receptors (DRs) D1R-D5R, but t …
Dopamine Receptor D5 Signaling Plays a Dual Role in Experimental Autoimmune Encephalomyelitis Potentiating Th17-Mediated Immunity and Favoring Suppressive Activity of Regulatory T-Cells.
Osorio-Barrios F, Prado C, Contreras F, Pacheco R. Osorio-Barrios F, et al. Front Cell Neurosci. 2018 Jul 10;12:192. doi: 10.3389/fncel.2018.00192. eCollection 2018. Front Cell Neurosci. 2018. PMID: 30042660 Free PMC article.
A number of studies have shown pharmacologic evidence indicating that stimulation of type I dopamine receptor (DR), favors T-helper-17 (Th17)-mediated immunity involved in experimental autoimmune encephalomyelitis (EAE) and in some other inflammatory disorders. Neve …
A number of studies have shown pharmacologic evidence indicating that stimulation of type I dopamine receptor (DR), favors T-helper-1 …
Dopamine, T cells and multiple sclerosis (MS).
Levite M, Marino F, Cosentino M. Levite M, et al. J Neural Transm (Vienna). 2017 May;124(5):525-542. doi: 10.1007/s00702-016-1640-4. Epub 2017 Mar 10. J Neural Transm (Vienna). 2017. PMID: 28283756 Review.
Dopamine also induces many direct and very potent effects on many DR-expressing immune cells, primarily T cells and dendritic cells. ...Dopamine-induced effects on T cells are dynamic, context-sensitive and determined by the
Dopamine also induces many direct and very potent effects on many DR-expressing immune cells, primarily T cel
The dopaminergic system in autoimmune diseases.
Pacheco R, Contreras F, Zouali M. Pacheco R, et al. Front Immunol. 2014 Mar 21;5:117. doi: 10.3389/fimmu.2014.00117. eCollection 2014. Front Immunol. 2014. PMID: 24711809 Free PMC article. Review.
The past decade has brought a burst of insights into the molecular mechanisms involved in neuroimmune communications mediated by dopamine. Studies of dendritic cells (DCs) revealed that they express the whole machinery to synthesize and store dopamine, …
The past decade has brought a burst of insights into the molecular mechanisms involved in neuroimmune communications mediated by dopamine
29 results