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Expression of M-Ficolin in human monocytes and macrophages.
Frankenberger M, Schwaeble W, Ziegler-Heitbrock L. Frankenberger M, et al. Mol Immunol. 2008 Mar;45(5):1424-30. doi: 10.1016/j.molimm.2007.08.014. Epub 2007 Oct 10. Mol Immunol. 2008. PMID: 17928056
M-Ficolin is a member of the ficolin family of proteins, which is expressed by monocytes. We have determined the expression of this gene in various populations of this lineage in man and found lower levels of M-Ficolin
M-Ficolin is a member of the ficolin family of proteins, which is expressed by monocytes. We have determi
The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma.
Honoré C, Rørvig S, Munthe-Fog L, Hummelshøj T, Madsen HO, Borregaard N, Garred P. Honoré C, et al. Mol Immunol. 2008 May;45(10):2782-9. doi: 10.1016/j.molimm.2008.02.005. Epub 2008 Mar 17. Mol Immunol. 2008. PMID: 18343499
Ficolin-1 (M-Ficolin) is a pattern recognition molecule of the complement system that is expressed by myeloid cells and type II alveolar epithelial cells. ...Ficolin-1 was found differentially expressed and synthesised by monocytes
Ficolin-1 (M-Ficolin) is a pattern recognition molecule of the complement system that is expressed by myeloid ce
Serum opsonin ficolin-A enhances host-fungal interactions and modulates cytokine expression from human monocyte-derived macrophages and neutrophils following Aspergillus fumigatus challenge.
Bidula S, Sexton DW, Schelenz S. Bidula S, et al. Med Microbiol Immunol. 2016 Apr;205(2):133-42. doi: 10.1007/s00430-015-0435-9. Epub 2015 Sep 4. Med Microbiol Immunol. 2016. PMID: 26337048
Using human monocyte-derived macrophages and neutrophils isolated from healthy donors, we investigated conidial association and fungal viability by flow cytometry and microscopy. ...Ficolin-A opsonization was observed to significantly enhance associati …
Using human monocyte-derived macrophages and neutrophils isolated from healthy donors, we investigated conidial associa …
M-ficolin is expressed on monocytes and is a lectin binding to N-acetyl-D-glucosamine and mediates monocyte adhesion and phagocytosis of Escherichia coli.
Teh C, Le Y, Lee SH, Lu J. Teh C, et al. Immunology. 2000 Oct;101(2):225-32. doi: 10.1046/j.1365-2567.2000.00099.x. Immunology. 2000. PMID: 11012776 Free PMC article.
In the present study, the FBG domain of M-ficolin was expressed and shown to bind to N-acetyl-D-glucosamine. M-ficolin mRNA was expressed in monocytes but not in the more differentiated macrophages and dendritic cells. ...Th …
In the present study, the FBG domain of M-ficolin was expressed and shown to bind to N-acetyl-D-glucosamine. M- …
Localization of the mouse defense lectin ficolin B in lysosomes of activated macrophages.
Runza VL, Hehlgans T, Echtenacher B, Zähringer U, Schwaeble WJ, Männel DN. Runza VL, et al. J Endotoxin Res. 2006;12(2):120-6. doi: 10.1179/096805106X102147. J Endotoxin Res. 2006. PMID: 16690015
In humans, two plasma ficolins have been identified and characterized, whereas a third cell-associated ficolin (M-ficolin) was found on monocyte surfaces. ...In addition, the data indicate that ficolin B expression is up-regulated …
In humans, two plasma ficolins have been identified and characterized, whereas a third cell-associated ficolin (M-fi
Biosynthesis of human ficolin, an Escherichia coli-binding protein, by monocytes: comparison with the synthesis of two macrophage-specific proteins, C1q and the mannose receptor.
Lu J, Le Y, Kon OL, Chan J, Lee SH. Lu J, et al. Immunology. 1996 Oct;89(2):289-94. doi: 10.1046/j.1365-2567.1996.d01-732.x. Immunology. 1996. PMID: 8943728 Free PMC article.
Ficolin mRNA was highly expressed in monocytes throughout the first 20 hr of adhesion. In contrast, C1q and mannose receptor mRNA were not detectable during the first 8 hr of adhesion, but were highly expressed by 20 hr. ...These results are consistent
Ficolin mRNA was highly expressed in monocytes throughout the first 20 hr of adhesion. In contrast, C1q and mannose rec
Ficolin-1 is up-regulated in leukocytes and glomeruli from microscopic polyangiitis patients.
Muso E, Okuzaki D, Kobayashi S, Iwasaki Y, Sakurai MA, Ito A, Nojima H. Muso E, et al. Autoimmunity. 2013 Dec;46(8):513-24. doi: 10.3109/08916934.2013.822073. Epub 2013 Aug 15. Autoimmunity. 2013. PMID: 23944633
Compared to normal control, several genes were up- or down-regulated in MPA patients, including up-regulation of the mRNA level of ficolin-1 (FCN1 or M-ficolin), an innate pattern recognition complement molecule. ...Many of the ficolin-1 dots were also …
Compared to normal control, several genes were up- or down-regulated in MPA patients, including up-regulation of the mRNA level of ficoli
Ficolin A and ficolin B are expressed in distinct ontogenic patterns and cell types in the mouse.
Liu Y, Endo Y, Homma S, Kanno K, Yaginuma H, Fujita T. Liu Y, et al. Mol Immunol. 2005 Jul;42(11):1265-73. doi: 10.1016/j.molimm.2004.11.019. Epub 2005 Jan 5. Mol Immunol. 2005. PMID: 15950722
The other human ficolin, M-ficolin, is a non-serum-type ficolin that is expressed in monocytes. Little is known about the physiological roles of ficolins. ...The cell types that express ficolin A mRNA in both adult li …
The other human ficolin, M-ficolin, is a non-serum-type ficolin that is expressed in monocytes
Tethering of Ficolin-1 to cell surfaces through recognition of sialic acid by the fibrinogen-like domain.
Honoré C, Rørvig S, Hummelshøj T, Skjoedt MO, Borregaard N, Garred P. Honoré C, et al. J Leukoc Biol. 2010 Jul;88(1):145-58. doi: 10.1189/jlb.1209802. Epub 2010 Apr 16. J Leukoc Biol. 2010. PMID: 20400674
Three Ficolins have been identified in humans: Ficolin-1 (M-Ficolin), Ficolin-2 (L-Ficolin), and Ficolin-3 (H-Ficolin). Ficolin-1 is the least-described of the Ficolins and is expressed by monocytes, gra …
Three Ficolins have been identified in humans: Ficolin-1 (M-Ficolin), Ficolin-2 (L-Ficolin), and …
The functional polymorphism Ala258Ser in the innate receptor gene ficolin-2 in the donor predicts improved renal transplant outcome.
Eikmans M, de Canck I, van der Pol P, Baan CC, Haasnoot GW, Mallat MJ, Vergunst M, de Meester E, Roodnat JI, Anholts JD, van Thielen M, Doxiadis II, de Fijter JW, van der Linden PJ, van Beelen E, van Kooten C, Kal-van Gestel JA, Peeters AM, Weimar W, Roelen DL, Rossau R, Claas FH. Eikmans M, et al. Transplantation. 2012 Sep 15;94(5):478-85. doi: 10.1097/TP.0b013e31825c5967. Transplantation. 2012. PMID: 22892990
Ficolin-2 messenger RNA expression was detected in pretransplantation biopsies from 69 donor grafts. Serum and tissue ficolin-2 levels were unaffected by genotype. Ficolin-2 protein, which bound to dying cells, was detected in donor kidneys in a passen
Ficolin-2 messenger RNA expression was detected in pretransplantation biopsies from 69 donor grafts. Serum and tissue ficol
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