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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 3
1993 1
1994 2
1995 2
1996 4
1997 2
1998 1
2000 6
2001 5
2002 3
2003 9
2004 12
2005 8
2006 15
2007 9
2008 8
2009 11
2010 10
2011 13
2012 11
2013 11
2014 8
2015 11
2016 5
2017 11
2018 7
2019 8
2020 4
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180 results
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Influence of inflammasome pathway activation in macrophages on the matrix metalloproteinase expression of human hepatic stellate cells.
Robert S, Gicquel T, Bodin A, Fautrel A, Barreto E, Victoni T, Lagente V, Boichot E. Robert S, et al. Int Immunopharmacol. 2019 Jul;72:12-20. doi: 10.1016/j.intimp.2019.03.060. Epub 2019 Apr 4. Int Immunopharmacol. 2019. PMID: 30954791
However, the mechanisms by which these complexes drive the liver's fibrogenic status remain unclear. We co-cultured differentiated macrophages (the THP-1 cell line or human monocyte-derived macrophages (MDMs)) with human hepatic fibroblasts (eit …
However, the mechanisms by which these complexes drive the liver's fibrogenic status remain unclear. We co-cultured differentiated ma …
A comparison of differences in the gene expression profiles of phorbol 12-myristate 13-acetate differentiated THP-1 cells and human monocyte-derived macrophage.
Kohro T, Tanaka T, Murakami T, Wada Y, Aburatani H, Hamakubo T, Kodama T. Kohro T, et al. J Atheroscler Thromb. 2004;11(2):88-97. doi: 10.5551/jat.11.88. J Atheroscler Thromb. 2004. PMID: 15153668 Free article.
In order to characterize the monocytic cell line THP-1 and its mature, macrophage-like form treated with phorbol 12-myristate 13-acetate (PMA), we have conducted an oligonucleotide microarray assay and compared the results with those from an assay of human
In order to characterize the monocytic cell line THP-1 and its mature, macrophage-like form treated with phorbol 12-myristate …
Monocyte-derived extracellular vesicles stimulate cytokine secretion and gene expression of matrix metalloproteinases by mesenchymal stem/stromal cells.
Gebraad A, Kornilov R, Kaur S, Miettinen S, Haimi S, Peltoniemi H, Mannerström B, Seppänen-Kaijansinkko R. Gebraad A, et al. FEBS J. 2018 Jun;285(12):2337-2359. doi: 10.1111/febs.14485. Epub 2018 May 18. FEBS J. 2018. PMID: 29732732 Free article.
We analysed gene expression and protein secretion by both adipose tissue-derived MSCs and bone marrow-derived MSCs after stimulation with EVs from lipopolysaccharide-activated primary human MCs and (mineral-resorbing) osteoclasts. ...MC-derived EVs also upreg …
We analysed gene expression and protein secretion by both adipose tissue-derived MSCs and bone marrow-derived MSCs after stimu …
Mechanisms involved in enhancement of matrix metalloproteinase-9 expression in macrophages by interleukin-33.
Ariyoshi W, Okinaga T, Chaweewannakorn W, Akifusa S, Nisihara T. Ariyoshi W, et al. J Cell Physiol. 2017 Dec;232(12):3481-3495. doi: 10.1002/jcp.25809. Epub 2017 Mar 27. J Cell Physiol. 2017. PMID: 28105703
Endothelial transmigration of macrophages is accomplished by matrix metalloproteinase (MMP)-induced degradation of the basement membrane and extracellular matrix components. ...The aim of this study was to elucidate the mechanisms underlying IL-33-induced MMP …
Endothelial transmigration of macrophages is accomplished by matrix metalloproteinase (MMP)-induced degradation of the basemen …
Significant alterations of the novel 15 gene signature identified from macrophage-tumor interactions in breast cancer.
Singh R, Dagar P, Pal S, Basu B, Shankar BS. Singh R, et al. Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):669-683. doi: 10.1016/j.bbagen.2017.12.004. Epub 2017 Dec 14. Biochim Biophys Acta Gen Subj. 2018. PMID: 29248526
BACKGROUND: Tumor microenvironment is composed of a largely altered extracellular matrix with different cell types. The complex interplay between macrophages and tumor cells through several soluble factors and signaling is an important factor in breast cancer …
BACKGROUND: Tumor microenvironment is composed of a largely altered extracellular matrix with different cell types. The comple …
A dual role of TGF-β in human osteoclast differentiation mediated by Smad1 versus Smad3 signaling.
Lee B, Oh Y, Jo S, Kim TH, Ji JD. Lee B, et al. Immunol Lett. 2019 Feb;206:33-40. doi: 10.1016/j.imlet.2018.12.003. Epub 2018 Dec 10. Immunol Lett. 2019. PMID: 30543834
TGF-β1 is highly expressed in the synovial tissue of patients with rheumatoid arthritis and is known as a cytokine that plays an important role in tissue repair and immune cell regulation. ...In this study, we examined the effect of TGF-β1 on osteoclast differentiat …
TGF-β1 is highly expressed in the synovial tissue of patients with rheumatoid arthritis and is known as a cytokine that plays an impo …
Alternatively activated macrophages derived from THP-1 cells promote the fibrogenic activities of human dermal fibroblasts.
Zhu Z, Ding J, Ma Z, Iwashina T, Tredget EE. Zhu Z, et al. Wound Repair Regen. 2017 May;25(3):377-388. doi: 10.1111/wrr.12532. Epub 2017 Apr 27. Wound Repair Regen. 2017. PMID: 28370945
Cell sorting was performed to purify M0 and M2 macrophages. Cell proliferation, collagen synthesis, myofibroblast formation, gene expression of anti-fibrotic and pro-fibrotic factors, MMP-1 activity, and cytokine concentration were investigated. ...M2
Cell sorting was performed to purify M0 and M2 macrophages. Cell proliferation, collagen synthesis, myofibroblast formation,
Evaluating the bromodomain protein BRD1 as a therapeutic target in rheumatoid arthritis.
Klein K, Kato M, Frank-Bertoncelj M, Kolling C, Ciurea A, Gay S, Ospelt C. Klein K, et al. Sci Rep. 2018 Jul 24;8(1):11125. doi: 10.1038/s41598-018-29127-w. Sci Rep. 2018. PMID: 30042400 Free PMC article.
The proliferation of SF was decreased upon BRD1 silencing, accompanied by the downregulation of genes involved in cell cycle regulation. ...In monocyte-derived macrophages (MDM), silencing of BRD1 decreased the LPS-induced expression of TNF-α, but did …
The proliferation of SF was decreased upon BRD1 silencing, accompanied by the downregulation of genes involved in cell cycle r …
Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation.
Lee WR, Chung CL, Hsiao CJ, Chou YC, Hsueh PJ, Yang PC, Jan JS, Cheng YW, Hsiao G. Lee WR, et al. Phytomedicine. 2012 Feb 15;19(3-4):270-7. doi: 10.1016/j.phymed.2011.11.012. Epub 2012 Jan 11. Phytomedicine. 2012. PMID: 22244537
There is much evidence indicating that human leukemic cells and monocytes/macrophages synthesize, and secrete, several matrix metalloproteinases (MMPs), and participate in the degradation of extracellular matrix components in tissue lesio …
There is much evidence indicating that human leukemic cells and monocytes/macrophages synthesize, and secrete, several …
MicroRNA-9 Inhibits NLRP3 Inflammasome Activation in Human Atherosclerosis Inflammation Cell Models through the JAK1/STAT Signaling Pathway.
Wang Y, Han Z, Fan Y, Zhang J, Chen K, Gao L, Zeng H, Cao J, Wang C. Wang Y, et al. Cell Physiol Biochem. 2017;41(4):1555-1571. doi: 10.1159/000470822. Epub 2017 Mar 27. Cell Physiol Biochem. 2017. PMID: 28334721 Free article.
We aimed to uncover the exact roles of miR-9 and downstream signaling pathways using in vitro human atherosclerosis models. METHODS: We used oxidized low-density lipoprotein (oxLDL)-stimulated human THP-1 derived macrophages, oxLDL-stimulated human primary pe …
We aimed to uncover the exact roles of miR-9 and downstream signaling pathways using in vitro human atherosclerosis models. METHODS: …
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