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Year Number of Results
1995 1
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2002 2
2003 2
2004 1
2005 1
2006 2
2007 1
2009 1
2010 3
2011 3
2013 2
2014 5
2015 5
2016 3
2017 3
2018 3
2019 2
2020 3
2021 4
2022 1
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The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway.
Li JY, Liao CH, Wang Q, Tan YJ, Luo R, Qiu Y, Ge XY. Li JY, et al. Virus Res. 2020 Sep;286:198074. doi: 10.1016/j.virusres.2020.198074. Epub 2020 Jun 23. Virus Res. 2020. PMID: 32589897 Free PMC article.
Innate immune response is critical for the host defense against viral infection and the dysregulation of the host innate immune responses probably aggravates SARS-CoV-2 infection, contributing to the high morbidity and lethality of COVID-19. ...All the three protein …
Innate immune response is critical for the host defense against viral infection and the dysregulation of the host innate immune respo …
Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics.
Moheimani F, Koops J, Williams T, Reid AT, Hansbro PM, Wark PA, Knight DA. Moheimani F, et al. Respir Res. 2018 Aug 2;19(1):145. doi: 10.1186/s12931-018-0851-7. Respir Res. 2018. PMID: 30068332 Free PMC article.
BACKGROUND: Specific microRNAs (miRNAs) play essential roles in airway remodeling in asthma. Infection with influenza A virus (IAV) may also magnify pre-existing airway remodeling leading to asthma exacerbation. ...Taqman mRNAs assays and immunoblotting were …
BACKGROUND: Specific microRNAs (miRNAs) play essential roles in airway remodeling in asthma. Infection with influenza A vir
Expression of transcription factor genes after influenza A virus infection.
Bussfeld D, Bacher M, Moritz A, Gemsa D, Sprenger H. Bussfeld D, et al. Immunobiology. 1997 Dec;198(1-3):291-8. doi: 10.1016/S0171-2985(97)80049-6. Immunobiology. 1997. PMID: 9442400
To explore long-term regulatory mechanisms, we investigated the induction of transcription factors on the gene expression level which may be important to substitute for metabolized transcription factor proteins after their activation. ... …
To explore long-term regulatory mechanisms, we investigated the induction of transcription factors on the gene expre
NMI Facilitates Influenza A Virus Infection by Promoting Degradation of IRF7 through TRIM21.
Ouyang W, Cen M, Yang L, Zhang W, Xia J, Xu F. Ouyang W, et al. Am J Respir Cell Mol Biol. 2021 Jul;65(1):30-40. doi: 10.1165/rcmb.2020-0391OC. Am J Respir Cell Mol Biol. 2021. PMID: 33761305
Acute respiratory infections caused by influenza A virus (IAV) spread widely and lead to substantial morbidity and mortality. ...Deficiency of NMI promoted the production of IFN-I and IFN-stimulated genes in vivo and in vitro. Reduced levels of NMI als …
Acute respiratory infections caused by influenza A virus (IAV) spread widely and lead to substantial morbidity and mort …
Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1.
Chauché C, Nogales A, Zhu H, Goldfarb D, Ahmad Shanizza AI, Gu Q, Parrish CR, Martínez-Sobrido L, Marshall JF, Murcia PR. Chauché C, et al. J Virol. 2018 Feb 12;92(5):e01875-17. doi: 10.1128/JVI.01875-17. Print 2018 Mar 1. J Virol. 2018. PMID: 29237841 Free PMC article.
Influenza A viruses (IAVs) are common pathogens of birds that occasionally establish endemic infections in mammals. ...However, the processes by which IAVs gain the ability to efficiently infect and transmit in mammals remain unclear. H3N8 equine influenza
Influenza A viruses (IAVs) are common pathogens of birds that occasionally establish endemic infections in mammals. ...However
Deletion of Irf3 and Irf7 Genes in Mice Results in Altered Interferon Pathway Activation and Granulocyte-Dominated Inflammatory Responses to Influenza A Infection.
Hatesuer B, Hoang HT, Riese P, Trittel S, Gerhauser I, Elbahesh H, Geffers R, Wilk E, Schughart K. Hatesuer B, et al. J Innate Immun. 2017;9(2):145-161. doi: 10.1159/000450705. Epub 2016 Nov 4. J Innate Immun. 2017. PMID: 27811478 Free PMC article.
The IFN regulatory factors IRF3 and IRF7 are key players in the regulation of type I and III IFN genes. In this study, we analyzed the role of IRF3 and IRF7 for the host response to IAV infections in Irf3-/-, Irf7-/-, and Irf3-/-Irf7-/- knockout mice. While t …
The IFN regulatory factors IRF3 and IRF7 are key players in the regulation of type I and III IFN genes. In this study, we anal …
Influenza A virus directly modulates mouse eosinophil responses.
LeMessurier KS, Rooney R, Ghoneim HE, Liu B, Li K, Smallwood HS, Samarasinghe AE. LeMessurier KS, et al. J Leukoc Biol. 2020 Jul;108(1):151-168. doi: 10.1002/JLB.4MA0320-343R. Epub 2020 May 9. J Leukoc Biol. 2020. PMID: 32386457 Free PMC article.
However, very little is known about how eosinophils respond to direct exposure to influenza A virus (IAV) or the microenvironment in which the viral burden is high. ...Siglec-F expression was altered in a subset of eosinophils after virus exposure, and …
However, very little is known about how eosinophils respond to direct exposure to influenza A virus (IAV) or the microenvironm …
Human influenza viruses activate an interferon-independent transcription of cellular antiviral genes: outcome with influenza A virus is unique.
Kim MJ, Latham AG, Krug RM. Kim MJ, et al. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10096-101. doi: 10.1073/pnas.152327499. Epub 2002 Jul 11. Proc Natl Acad Sci U S A. 2002. PMID: 12114540 Free PMC article.
Consequently, the IFN regulatory factor-3 transcription factor, which is required for the transcription of ISRE-controlled genes, is activated after influenza B virus infection. ...These mature cellular antiviral mRNAs are n …
Consequently, the IFN regulatory factor-3 transcription factor, which is required for the transcription of ISRE- …
SH3GLB2/endophilin B2 regulates lung homeostasis and recovery from severe influenza A virus infection.
Fino KK, Yang L, Silveyra P, Hu S, Umstead TM, DiAngelo S, Halstead ES, Cooper TK, Abraham T, Takahashi Y, Zhou Z, Wang HG, Chroneos ZC. Fino KK, et al. Sci Rep. 2017 Aug 4;7(1):7262. doi: 10.1038/s41598-017-07724-5. Sci Rep. 2017. PMID: 28779131 Free PMC article.
Here, we investigated the role of endophilin B2 (B2) in susceptibility to severe influenza infection. WT and B2-deficient mice were infected with H1N1 PR8 by intranasal administration and course of influenza pneumonia, inflammatory, and tissue response …
Here, we investigated the role of endophilin B2 (B2) in susceptibility to severe influenza infection. WT and B2-deficient mice …
Alteration of gene expression in human middle ear epithelial cells induced by influenza A virus and its implication for the pathogenesis of otitis media.
Tong HH, Long JP, Li D, DeMaria TF. Tong HH, et al. Microb Pathog. 2004 Oct;37(4):193-204. doi: 10.1016/j.micpath.2004.06.012. Microb Pathog. 2004. PMID: 15458780
Alterations of mRNA expression in 142 out of approximately 12,600 genes were observed at 24h after virus infection. Of these 142 genes with altered expression, interferon inducible genes, chemokine and cytokine genes, pro- a …
Alterations of mRNA expression in 142 out of approximately 12,600 genes were observed at 24h after virus infection
44 results