Gamma interferon and lipopolysaccharide interact at the level of transcription to induce tumor necrosis factor alpha expression.
Infect Immun. 2001.
PMID: 11292697
Free PMC article.
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Regulation of the MIR155 host gene in physiological and pathological processes.
Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14.
Gene. 2013.
PMID: 23246696
Review.
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing complex to inhibit gene expression by targeting mRNAs for translational repr …
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in posttranscriptional gene regulation by acting a …
Gamma interferon and lipopolysaccharide interact at the level of transcription to induce tumor necrosis factor alpha expression.
Infect Immun. 2001 May;69(5):2847-52. doi: 10.1128/IAI.69.5.2847-2852.2001.
Infect Immun. 2001.
PMID: 11292697
Free PMC article.
Lipopolysaccharide (LPS) is a very potent inducer of tumor necrosis factor alpha (TNF-alpha) expression from monocytes and macrophages. ...This study demonstrates that IFN-gamma can upregulate the effect of LPS at the …
Lipopolysaccharide (LPS) is a very potent inducer of tumor necrosis factor alpha (TNF-alpha …
Gamma interferon augments macrophage activation by lipopolysaccharide by two distinct mechanisms, at the signal transduction level and via an autocrine mechanism involving tumor necrosis factor alpha and interleukin-1.
Infect Immun. 1999 Jan;67(1):206-12. doi: 10.1128/IAI.67.1.206-212.1999.
Infect Immun. 1999.
PMID: 9864217
Free PMC article.
The mechanisms of this synergistic toxicity are not known. We considered the possibility that an interaction between the LPS-induced NF-kappaB and IFN-gamma-induced JAK-STAT pathways at the pretranscriptional level may enhance the LPS-induced …
The mechanisms of this synergistic toxicity are not known. We considered the possibility that an interaction between the LPS-induc …
C/EBPbeta mediates synergistic upregulation of gene expression by interferon-gamma and tumor necrosis factor-alpha in bone marrow-derived mesenchymal stem cells.
Stem Cells. 2009 Apr;27(4):942-8. doi: 10.1002/stem.22.
Stem Cells. 2009.
PMID: 19353522
Free PMC article.
MSC function is modulated by cytokines, since inflammatory cytokines, such as interferon-gamma (IFNgamma) concomitant with tumor necrosis factor-alpha (TNFalpha), induce their immunoregulatory capability. ...We conclude that C/EBPb …
MSC function is modulated by cytokines, since inflammatory cytokines, such as interferon-gamma (IFNgamma) concomitant with …
Diverse action of lipoteichoic acid and lipopolysaccharide on neuroinflammation, blood-brain barrier disruption, and anxiety in mice.
Brain Behav Immun. 2017 Feb;60:174-187. doi: 10.1016/j.bbi.2016.10.011. Epub 2016 Oct 14.
Brain Behav Immun. 2017.
PMID: 27751870
Free PMC article.
Since LTA preparations may be contaminated by LPS, an extract of LTA (LTA(extract)), purified LTA (LTA(pure)), and pure LPS (LPS(ultrapure)) were compared with each other in their effects on molecular and behavioral parameters 3h after intraperitoneal (i.p.) injection to male C57 …
Since LTA preparations may be contaminated by LPS, an extract of LTA (LTA(extract)), purified LTA (LTA(pure)), and pure LPS (LPS(ultrapure)) …
Central and peripheral immune responses to low-dose lipopolysaccharide in a mouse model of the 15q13.3 microdeletion.
Cytokine. 2020 Feb;126:154879. doi: 10.1016/j.cyto.2019.154879. Epub 2019 Oct 16.
Cytokine. 2020.
PMID: 31629107
In control saline injected animals, all measured cytokines were at or below detection limits, whereas LPS significantly increased serum levels of interleukin 1beta (IL-1beta), tumor necrosis factor alpha (TNF-alpha), IL-6 and IL-10, but n …
In control saline injected animals, all measured cytokines were at or below detection limits, whereas LPS significantly increased serum l …
Potentiation of tumor necrosis factor-alpha expression by YC-1 in alveolar macrophages through a cyclic GMP-independent pathway.
Biochem Pharmacol. 2003 Jul 1;66(1):149-56. doi: 10.1016/s0006-2952(03)00202-8.
Biochem Pharmacol. 2003.
PMID: 12818375
Using cultured rat alveolar NR 8383 macrophages, this study investigated the effect of YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole], a soluble guanylyl cyclase (sGC) activator, on the production of tumor necrosis factor-alpha (TNF alpha …
Using cultured rat alveolar NR 8383 macrophages, this study investigated the effect of YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole …
Lipopolysaccharide-induced interleukin-10 in mice: role of endogenous tumor necrosis factor-alpha.
Eur J Immunol. 1995 Oct;25(10):2888-93. doi: 10.1002/eji.1830251027.
Eur J Immunol. 1995.
PMID: 7589088
We have examined the interactions of the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) with IL-10. ...Treatment of mice with neutralizing anti-mouse TNF-alpha antiserum significantly increased LPS-induced …
We have examined the interactions of the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-al …
Deficiency of XIAP leads to sensitization for Chlamydophila pneumoniae pulmonary infection and dysregulation of innate immune response in mice.
J Biol Chem. 2010 Jun 25;285(26):20291-302. doi: 10.1074/jbc.M109.096297. Epub 2010 Apr 28.
J Biol Chem. 2010.
PMID: 20427267
Free PMC article.
Hyper-secretion of tumor necrosis factor-alpha and lower NO in LPS-treated KO mouse macrophages revealed its regulatory role in inflammatory responses. Unexpectedly, activating stimuli like LPS, tumor necrosis factor-alpha, …
Hyper-secretion of tumor necrosis factor-alpha and lower NO in LPS-treated KO mouse macrophages revealed its reg …
Expression of monocyte chemotactic protein-3 in human monocytes and endothelial cells.
Eur Cytokine Netw. 1997 Sep;8(3):271-4.
Eur Cytokine Netw. 1997.
PMID: 9346360
Free article.
Unstimulated human umbilical vein EC and monocytes did not express MCP-3. Bacterial lipopolysaccharides (LPS), IL-1 and TNF induced low, but appreciable levels of MCP-3 transcripts. Interferon-gamma was a much weaker, but neverthel …
Unstimulated human umbilical vein EC and monocytes did not express MCP-3. Bacterial lipopolysaccharides (LPS), IL-1 and TNF …
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