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Page 1
Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases.
Kapellos TS, Bonaguro L, Gemünd I, Reusch N, Saglam A, Hinkley ER, Schultze JL. Kapellos TS, et al. Front Immunol. 2019 Aug 30;10:2035. doi: 10.3389/fimmu.2019.02035. eCollection 2019. Front Immunol. 2019. PMID: 31543877 Free PMC article. Review.
Human monocytes are divided in three major populations; classical (CD14(+)CD16(-)), non-classical (CD14(dim)CD16(+)), and intermediate (CD14(+)CD16(+)). ...Furthermore, we shed light on the role of these plastic immune cells in already recognized and emerging
Human monocytes are divided in three major populations; classical (CD14(+)CD16(-)), non-classical (CD14(dim)CD16(+)), a
Macrophages: versatile players in renal inflammation and fibrosis.
Tang PM, Nikolic-Paterson DJ, Lan HY. Tang PM, et al. Nat Rev Nephrol. 2019 Mar;15(3):144-158. doi: 10.1038/s41581-019-0110-2. Epub 2019 Jan 28. Nat Rev Nephrol. 2019. PMID: 30692665 Review.
Macrophages have important roles in immune surveillance and in the maintenance of kidney homeostasis; their response to renal injury varies enormously depending on the nature and duration of the insult. Macrophages can adopt a variety of phenotypes: at one extreme, M1 pro- …
Macrophages have important roles in immune surveillance and in the maintenance of kidney homeostasis; their response to renal injury varies …
Vascular Macrophages in Atherosclerosis.
Xu H, Jiang J, Chen W, Li W, Chen Z. Xu H, et al. J Immunol Res. 2019 Dec 1;2019:4354786. doi: 10.1155/2019/4354786. eCollection 2019. J Immunol Res. 2019. PMID: 31886303 Free PMC article. Review.
It has been well established that atherosclerosis is not only a metabolic disorder but also a chronic, sterile, and maladaptive inflammatory process encompassing both innate and adaptive immunity. ...This article reviews the functions of macrophages in different sta …
It has been well established that atherosclerosis is not only a metabolic disorder but also a chronic, sterile, and maladaptive in
Abstracts of Presentations at the Association of Clinical Scientists 143rd Meeting Louisville, KY May 11-14,2022.
[No authors listed] [No authors listed] Ann Clin Lab Sci. 2022 May;52(3):511-525. Ann Clin Lab Sci. 2022. PMID: 35777803
Hepatic steatosis is an early occurrence in all three forms of liver disease, and they often share common pathways to disease progression/severity. ...Upon completion of this activity, participants should be able to understand the utility of MassARRAY system in mole …
Hepatic steatosis is an early occurrence in all three forms of liver disease, and they often share common pathways to disease
Macrophages in the kidney in health, injury and repair.
Bell RMB, Conway BR. Bell RMB, et al. Int Rev Cell Mol Biol. 2022;367:101-147. doi: 10.1016/bs.ircmb.2022.01.005. Epub 2022 Feb 28. Int Rev Cell Mol Biol. 2022. PMID: 35461656
Danger-associated molecules released from injured kidney cells may activate macrophages toward a pro-inflammatory phenotype, mediating further recruitment of inflammatory cells, exacerbating renal injury and activating renal fibroblasts to promote scarring. . …
Danger-associated molecules released from injured kidney cells may activate macrophages toward a pro-inflammatory phenotype, m …
Immune Response Dysfunction in Chronic Lymphocytic Leukemia: Dissecting Molecular Mechanisms and Microenvironmental Conditions.
Arruga F, Gyau BB, Iannello A, Vitale N, Vaisitti T, Deaglio S. Arruga F, et al. Int J Mol Sci. 2020 Mar 6;21(5):1825. doi: 10.3390/ijms21051825. Int J Mol Sci. 2020. PMID: 32155826 Free PMC article. Review.
Representing the major cause of morbidity and mortality for chronic lymphocytic leukemia (CLL) patients, immunosuppression is a common feature of the disease. ...Likewise, differentiation of monocytes towards a suppressive M2-like phenotype is i …
Representing the major cause of morbidity and mortality for chronic lymphocytic leukemia (CLL) patients, immunosuppression is …
Mechanisms of cardiac fibrosis in inflammatory heart disease.
Kania G, Blyszczuk P, Eriksson U. Kania G, et al. Trends Cardiovasc Med. 2009 Nov;19(8):247-52. doi: 10.1016/j.tcm.2010.02.005. Trends Cardiovasc Med. 2009. PMID: 20447565 Review.
Dilated cardiomyopathy is an important cause of heart failure and often results from virus-triggered myocarditis. Monocytes and monocyte-like cells represent a major subset of heart-infiltrating cells at the injury site. ...Thus, they are critically in …
Dilated cardiomyopathy is an important cause of heart failure and often results from virus-triggered myocarditis. Monocytes and mo
Altered monocytic phenotypes are linked with systemic inflammation and may be linked to mortality in dialysis patients.
Brandt S, Ewert L, Scurt FG, Reichardt C, Lindquist JA, Gorny X, Isermann B, Mertens PR. Brandt S, et al. Sci Rep. 2019 Dec 13;9(1):19103. doi: 10.1038/s41598-019-55592-y. Sci Rep. 2019. PMID: 31836803 Free PMC article.
The major causes for increased morbidity and mortality among chronic kidney disease patients are cardiovascular diseases and infection. A causal link between an activated immune system and aggravated atherosclerosis has been postulated that skews the s …
The major causes for increased morbidity and mortality among chronic kidney disease patients are cardiovascular dise
Canine sino-nasal aspergillosis: parallels with human disease.
Day MJ. Day MJ. Med Mycol. 2009;47 Suppl 1:S315-23. doi: 10.1080/13693780802056038. Epub 2008 Jun 23. Med Mycol. 2009. PMID: 18608893 Review.
The fungus does not invade beneath the level of mucosal epithelium but incites a severe chronic inflammatory response that leads to local destruction of nasal bone. ...Additionally, there is significant transcription of the IL-10 gene consistent with local immunosup …
The fungus does not invade beneath the level of mucosal epithelium but incites a severe chronic inflammatory response that lea …
Characteristics of systemic inflammation in hepatitis B-precipitated ACLF: Differentiate it from No-ACLF.
Wu W, Yan H, Zhao H, Sun W, Yang Q, Sheng J, Shi Y. Wu W, et al. Liver Int. 2018 Feb;38(2):248-257. doi: 10.1111/liv.13504. Epub 2017 Jul 18. Liver Int. 2018. PMID: 28646630
BACKGROUND & AIMS: Patients with severe exacerbation of chronic hepatitis B (SE-CHB) are at risk of developing acute-on-chronic liver failure (ACLF). ...Cytokine measurements, leucocyte phenotyping and whole blood transcriptomic analyses were performed us …
BACKGROUND & AIMS: Patients with severe exacerbation of chronic hepatitis B (SE-CHB) are at risk of developing acute-on-chroni
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