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Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15.
Musso T, Calosso L, Zucca M, Millesimo M, Ravarino D, Giovarelli M, Malavasi F, Ponzi AN, Paus R, Bulfone-Paus S. Musso T, et al. Blood. 1999 May 15;93(10):3531-9. Blood. 1999. PMID: 10233906 Free article.
We demonstrate here that biologically active IL-15 is indeed detectable in a constitutively expressed, membrane-bound form on normal human monocytes, as well as on monocytic cell lines (MONO-MAC-6, THP-1, and U937), b …
We demonstrate here that biologically active IL-15 is indeed detectable in a constitutively expressed, membra
Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines.
Gruss HJ, DaSilva N, Hu ZB, Uphoff CC, Goodwin RG, Drexler HG. Gruss HJ, et al. Leukemia. 1994 Dec;8(12):2083-94. Leukemia. 1994. PMID: 7528856
Recent work established CD30 as a member of the tumor necrosis factor/nerve growth factor receptor superfamily whose ligand (CD30L) has also been cloned and expressed; CD30L is active as membrane-bound type II glycoprotein. Here, CD30L mRNA expressi
Recent work established CD30 as a member of the tumor necrosis factor/nerve growth factor receptor superfamily whose ligand (CD30L) has also …
Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55.
Abbott RJ, Spendlove I, Roversi P, Fitzgibbon H, Knott V, Teriete P, McDonnell JM, Handford PA, Lea SM. Abbott RJ, et al. J Biol Chem. 2007 Jul 27;282(30):22023-32. doi: 10.1074/jbc.M702588200. Epub 2007 Apr 20. J Biol Chem. 2007. PMID: 17449467 Free article.
CD97, the archetypal member of the EGF-TM7 protein family, is constitutively expressed on granulocytes and monocytes and rapidly up-regulated on T and B cells following activation. ...Here, we demonstrate that blocking the interaction between CD55 on …
CD97, the archetypal member of the EGF-TM7 protein family, is constitutively expressed on granulocytes and monocytes an …
IL-1 beta enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): a mechanism for T cell-independent DC activation.
Luft T, Jefford M, Luetjens P, Hochrein H, Masterman KA, Maliszewski C, Shortman K, Cebon J, Maraskovsky E. Luft T, et al. J Immunol. 2002 Jan 15;168(2):713-22. doi: 10.4049/jimmunol.168.2.713. J Immunol. 2002. PMID: 11777965 Clinical Trial.
CD40 ligand (CD40L) is a membrane-bound molecule expressed by activated T cells. CD40L potently induces dendritic cell (DC) maturation and IL-12p70 secretion and plays a critical role during T cell priming in the lymph nodes. ...Finally, DC activate
CD40 ligand (CD40L) is a membrane-bound molecule expressed by activated T cells. CD40L potently induces dendriti …