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Human dendritic cell line models for DC differentiation and clinical DC vaccination studies.
Santegoets SJ, van den Eertwegh AJ, van de Loosdrecht AA, Scheper RJ, de Gruijl TD. Santegoets SJ, et al. J Leukoc Biol. 2008 Dec;84(6):1364-73. doi: 10.1189/jlb.0208092. Epub 2008 Jul 29. J Leukoc Biol. 2008. PMID: 18664532 Review.
This review discusses the different human DC cell line differentiation models described so far. Based on the available data, characteristics that determine the ability of leukemia cells to differentiate along the different p …
This review discusses the different human DC cell line differentiation models described so far. Ba …
Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.
Shay JW, Homma N, Zhou R, Naseer MI, Chaudhary AG, Al-Qahtani M, Hirokawa N, Goudarzi M, Fornace AJ Jr, Baeesa S, Hussain D, Bangash M, Alghamdi F, Schulten HJ, Carracedo A, Khan I, Qashqari H, Madkhali N, Saka M, Saini KS, Jamal A, Al-Maghrabi J, Abuzenadah A, Chaudhary A, Al Qahtani M, Damanhouri G, Alkhatabi H, Goodeve A, Crookes L, Niksic N, Beauchamp N, Abuzenadah AM, Vaught J, Budowle B, Assidi M, Buhmeida A, Al-Maghrabi J, Buhmeida A, Assidi M, Merdad L, Kumar S, Miura S, Gomez K, Carracedo A, Rasool M, Rebai A, Karim S, Eldin HFN, Abusamra H, Alhathli EM, Salem N, Al-Qahtani MH, Kumar S, Faheem H, Agarwa A, Nieschlag E, Wistuba J, Damm OS, Beg MA, Abdel-Meguid TA, Mosli HA, Bajouh OS, Abuzenadah AM, Al-Qahtani MH, Coskun S, Abu-Elmagd M, Buhmeida A, Dallol A, Al-Maghrabi J, Hakamy S, Al-Qahtani W, Al-Harbi A, Hussain S, Assidi M, Al-Qahtani M, Abuzenadah A, Ozkosem B, DuBois R, Messaoudi SS, Dandana MT, Mahjoub T, Almawi WY, Abdalla S, Al-Aama MN, Elzawahry A, Takahashi T, Mimaki S, Furukawa E, Nakatsuka R, Kurosaka I, Nishigaki T, Nakamura H, Serada S, Naka T, Hirota S, Shibata T, Tsuchihara K, Nishida T, Kato M, Mehmood S, Ashraf NM, Asif A, Bilal M, Mehmood MS, Hussain … See abstract for full author list ➔ Shay JW, et al. BMC Genomics. 2016 Jul 20;17 Suppl 6(Suppl 6):487. doi: 10.1186/s12864-016-2858-0. BMC Genomics. 2016. PMID: 27454254 Free PMC article.
Safia S Messaoudi, Maryam T Dandana, Touhami Mahjoub, Wassim Y Almawi P4 Effect of environmental factors on gene-gene and gene-environment reactions: model and theoretical study applied to environmental interventions using genotype S. ...El-Bassyouni, Marwa I. Sheha …
Safia S Messaoudi, Maryam T Dandana, Touhami Mahjoub, Wassim Y Almawi P4 Effect of environmental factors on gene-gene and gene-environment r …
Rabies virus expressing dendritic cell-activating molecules enhances the innate and adaptive immune response to vaccination.
Wen Y, Wang H, Wu H, Yang F, Tripp RA, Hogan RJ, Fu ZF. Wen Y, et al. J Virol. 2011 Feb;85(4):1634-44. doi: 10.1128/JVI.01552-10. Epub 2010 Nov 24. J Virol. 2011. PMID: 21106736 Free PMC article.
Our previous studies indicated that recruitment and/or activation of dendritic cells (DCs) is important in enhancing the protective immune responses against rabies virus (RABV) (L. ...Morimoto, and Z. F. Fu, J. Virol. 84:9642-9648). To address the importance …
Our previous studies indicated that recruitment and/or activation of dendritic cells (DCs) is important in enhancing th …
Inducing antitumor T cell immunity: comparative functional analysis of interstitial versus Langerhans dendritic cells in a human cell line model.
Santegoets SJ, Bontkes HJ, Stam AG, Bhoelan F, Ruizendaal JJ, van den Eertwegh AJ, Hooijberg E, Scheper RJ, de Gruijl TD. Santegoets SJ, et al. J Immunol. 2008 Apr 1;180(7):4540-9. doi: 10.4049/jimmunol.180.7.4540. J Immunol. 2008. PMID: 18354176
Dendritic cells (DC) are increasingly applied as a cellular adjuvant in immunotherapy of cancer. Two major myeloid DC subsets are recognized: interstitial DC (IDC) that infiltrate connective tissues and Langerhans cells (LC) that line
Dendritic cells (DC) are increasingly applied as a cellular adjuvant in immunotherapy of cancer. Two major myeloid D
NOD/scid IL-2Rg(null) mice: a preclinical model system to evaluate human dendritic cell-based vaccine strategies in vivo.
Spranger S, Frankenberger B, Schendel DJ. Spranger S, et al. J Transl Med. 2012 Feb 25;10:30. doi: 10.1186/1479-5876-10-30. J Transl Med. 2012. PMID: 22364226 Free PMC article.
Here we describe a humanized mouse model to assess the efficacy of various human dendritic cell (DC) preparations. ...In addition, ex vivo analyses of human CD3+ T cells recovered from the spleens of these mice are also possible, i …
Here we describe a humanized mouse model to assess the efficacy of various human dendritic cell (DC) prep …
Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells.
Balan S, Ollion V, Colletti N, Chelbi R, Montanana-Sanchis F, Liu H, Vu Manh TP, Sanchez C, Savoret J, Perrot I, Doffin AC, Fossum E, Bechlian D, Chabannon C, Bogen B, Asselin-Paturel C, Shaw M, Soos T, Caux C, Valladeau-Guilemond J, Dalod M. Balan S, et al. J Immunol. 2014 Aug 15;193(4):1622-35. doi: 10.4049/jimmunol.1401243. Epub 2014 Jul 9. J Immunol. 2014. PMID: 25009205 Free PMC article.
Human monocyte-derived dendritic cell (MoDC) have been used in the clinic with moderately encouraging results. ...Hence, it is feasible to generate high numbers of bona fide XCR1(+) human DC in vitro as a model to decipher the func
Human monocyte-derived dendritic cell (MoDC) have been used in the clinic with moderately encouraging results. .
Tumor cell lysate-pulsed human dendritic cells induce a T-cell response against pancreatic carcinoma cells: an in vitro model for the assessment of tumor vaccines.
Schnurr M, Galambos P, Scholz C, Then F, Dauer M, Endres S, Eigler A. Schnurr M, et al. Cancer Res. 2001 Sep 1;61(17):6445-50. Cancer Res. 2001. PMID: 11522639
Dendritic cells (DCs) are potent antigen-presenting cells and play a pivotal role in T cell-mediated immunity. ...This in vitro model can be applied to compare different strategies in the development of DC-based tumor vac
Dendritic cells (DCs) are potent antigen-presenting cells and play a pivotal role in T cell-mediat
Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X.
Jung ID, Shin SJ, Lee MG, Kang TH, Han HD, Lee SJ, Kim WS, Kim HM, Park WS, Kim HW, Yun CH, Lee EK, Wu TC, Park YM. Jung ID, et al. J Immunol. 2014 Aug 1;193(3):1233-45. doi: 10.4049/jimmunol.1400656. Epub 2014 Jul 2. J Immunol. 2014. PMID: 24990079 Free PMC article.
Despite the potential for stimulation of robust antitumor immunity by dendritic cells (DCs), clinical applications of DC-based immunotherapy are limited by the low potency in generating tumor Ag-specific T cell responses. Therefore, optimal cond …
Despite the potential for stimulation of robust antitumor immunity by dendritic cells (DCs), clinical applications of …
IFN-gamma-producing human invariant NKT cells promote tumor-associated antigen-specific cytotoxic T cell responses.
Moreno M, Molling JW, von Mensdorff-Pouilly S, Verheijen RH, Hooijberg E, Kramer D, Reurs AW, van den Eertwegh AJ, von Blomberg BM, Scheper RJ, Bontkes HJ. Moreno M, et al. J Immunol. 2008 Aug 15;181(4):2446-54. doi: 10.4049/jimmunol.181.4.2446. J Immunol. 2008. PMID: 18684935
Herein we present results of investigations on the effects of human iNKT cells on Ag-specific CTL responses. iNKT cells were expanded using alphaGC-pulsed allogeneic DC derived from the acute myeloid leukemia cell line MUTZ-3, transduced …
Herein we present results of investigations on the effects of human iNKT cells on Ag-specific CTL responses. iNKT cells
The Tat-conjugated N-terminal region of mucin antigen 1 (MUC1) induces protective immunity against MUC1-expressing tumours.
Yang H, Cho NH, Seong SY. Yang H, et al. Clin Exp Immunol. 2009 Nov;158(2):174-85. doi: 10.1111/j.1365-2249.2009.03997.x. Epub 2009 Jul 17. Clin Exp Immunol. 2009. PMID: 19737144 Free PMC article.
Here, we evaluated N-terminal region (2-147 amino acids) of MUC1 (MUC1-N) for dendritic cell (DC)-based cancer immunotherapy. We used Esherichia coli-derived MUC1-N that was fused to the protein transduction domain of human immunodeficiency virus Tat p …
Here, we evaluated N-terminal region (2-147 amino acids) of MUC1 (MUC1-N) for dendritic cell (DC)-based cancer immunoth …
13 results