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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 2
1978 1
1979 2
1980 3
1981 4
1982 2
1983 3
1984 7
1985 9
1986 6
1987 8
1988 10
1989 6
1990 10
1991 11
1992 22
1993 17
1994 17
1995 24
1996 16
1997 13
1998 15
1999 16
2000 18
2001 22
2002 26
2003 30
2004 23
2005 20
2006 27
2007 28
2008 40
2009 39
2010 47
2011 37
2012 45
2013 66
2014 59
2015 66
2016 62
2017 66
2018 79
2019 64
2020 63
2021 5
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Search Results

1,062 results
Results by year
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Page 1
Development of monocytes, macrophages, and dendritic cells.
Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K. Geissmann F, et al. Science. 2010 Feb 5;327(5966):656-61. doi: 10.1126/science.1178331. Science. 2010. PMID: 20133564 Free PMC article. Review.
Monocytes and macrophages are critical effectors and regulators of inflammation and the innate immune response, the immediate arm of the immune system. Dendritic cells initiate and regulate the highly pathogen-specific adaptive immune responses and are …
Monocytes and macrophages are critical effectors and regulators of inflammation and the innate immune response, the immediate …
The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis.
Duan M, Hibbs ML, Chen W. Duan M, et al. Immunol Cell Biol. 2017 Mar;95(3):225-235. doi: 10.1038/icb.2016.97. Epub 2016 Sep 27. Immunol Cell Biol. 2017. PMID: 27670791 Review.
Findings from fate mapping, parabiosis, transcriptome and epigenome profiling studies now indicate that tissue macrophage and monocyte subsets possess specialized functions which differentially impact homoeostatic tolerance, pathogen detection and pathogen ki …
Findings from fate mapping, parabiosis, transcriptome and epigenome profiling studies now indicate that tissue macrophage and monocyte …
Sinomenine Inhibits the Progression of Rheumatoid Arthritis by Regulating the Secretion of Inflammatory Cytokines and Monocyte/Macrophage Subsets.
Liu W, Zhang Y, Zhu W, Ma C, Ruan J, Long H, Wang Y. Liu W, et al. Front Immunol. 2018 Sep 26;9:2228. doi: 10.3389/fimmu.2018.02228. eCollection 2018. Front Immunol. 2018. PMID: 30319663 Free PMC article. Clinical Trial.
To explore the mechanism of SIN anti-inflammatory function, RA-associated monocyte/macrophage subsets were determined using flow cytometry in CIA mouse model and RA patients, both treated with SIN. ...These data indicated that SIN regulates the secretion of multiple …
To explore the mechanism of SIN anti-inflammatory function, RA-associated monocyte/macrophage subsets were determined using fl …
Immunosuppression and monocyte subsets.
Rogacev KS, Zawada AM, Hundsdorfer J, Achenbach M, Held G, Fliser D, Heine GH. Rogacev KS, et al. Nephrol Dial Transplant. 2015 Jan;30(1):143-53. doi: 10.1093/ndt/gfu315. Epub 2014 Oct 13. Nephrol Dial Transplant. 2015. PMID: 25313167
BACKGROUND: Monocytes are critical in innate immunity and transplantation. Three monocyte subsets exist, CD14(++)CD16(-), CD14(++)CD16(+) and CD14(+)CD16(++) monocytes; cell counts of CD14(++)CD16(+) and CD14(+)CD16(++) monocytes are increased i …
BACKGROUND: Monocytes are critical in innate immunity and transplantation. Three monocyte subsets exist, CD14(++)CD16(- …
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections.
Remy KE, Mazer M, Striker DA, Ellebedy AH, Walton AH, Unsinger J, Blood TM, Mudd PA, Yi DJ, Mannion DA, Osborne DF, Martin RS, Anand NJ, Bosanquet JP, Blood J, Drewry AM, Caldwell CC, Turnbull IR, Brakenridge SC, Moldwawer LL, Hotchkiss RS. Remy KE, et al. JCI Insight. 2020 Sep 3;5(17):e140329. doi: 10.1172/jci.insight.140329. JCI Insight. 2020. PMID: 32687484 Free PMC article.
A key explanation for the inability to address this controversy has been the lack of diagnostic tools to evaluate immune function in COVID-19 infections. ELISpot, a highly sensitive, functional immunoassay, was employed in 27 patients with COVID-19, 51 patients with sepsis …
A key explanation for the inability to address this controversy has been the lack of diagnostic tools to evaluate immune function in …
T Cell- and Monocyte-Specific RNA-Sequencing Analysis in Septic and Nonseptic Critically Ill Patients and in Patients with Cancer.
Washburn ML, Wang Z, Walton AH, Goedegebuure SP, Figueroa DJ, Van Horn S, Grossman J, Remlinger K, Madsen H, Brown J, Srinivasan R, Wolf AI, Berger SB, Yi VN, Hawkins WG, Fields RC, Hotchkiss RS. Washburn ML, et al. J Immunol. 2019 Oct 1;203(7):1897-1908. doi: 10.4049/jimmunol.1900560. Epub 2019 Sep 4. J Immunol. 2019. PMID: 31484735 Free PMC article. Clinical Trial.
Sepsis is characterized as life-threatening organ dysfunction caused by a dysregulated host immune response to infection. The purpose of this investigation was to determine the differential effect of sepsis on innate versus adaptive immunity, in humans, by examining …
Sepsis is characterized as life-threatening organ dysfunction caused by a dysregulated host immune response to infection. The …
Macrophage heterogeneity in liver injury and fibrosis.
Tacke F, Zimmermann HW. Tacke F, et al. J Hepatol. 2014 May;60(5):1090-6. doi: 10.1016/j.jhep.2013.12.025. Epub 2014 Jan 8. J Hepatol. 2014. PMID: 24412603 Free article. Review.
Kupffer cells appear essential for sensing tissue injury and initiating inflammatory responses, while infiltrating Ly-6C(+) monocyte-derived macrophages are linked to chronic inflammation and fibrogenesis. ...Understanding the mechanisms that regulate hepatic macrophage he …
Kupffer cells appear essential for sensing tissue injury and initiating inflammatory responses, while infiltrating Ly-6C(+) monocyte- …
Clinical Relevance and Suppressive Capacity of Human Myeloid-Derived Suppressor Cell Subsets.
Lang S, Bruderek K, Kaspar C, Höing B, Kanaan O, Dominas N, Hussain T, Droege F, Eyth C, Hadaschik B, Brandau S. Lang S, et al. Clin Cancer Res. 2018 Oct 1;24(19):4834-4844. doi: 10.1158/1078-0432.CCR-17-3726. Epub 2018 Jun 18. Clin Cancer Res. 2018. PMID: 29914893 Free article.
Purpose: Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of pathologically expanded myeloid cells with immunosuppressive activity. In human disease, three major MDSC subpopulations can be defined as monocytic (M-MDSC), granulocytic [polymorphonucle …
Purpose: Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of pathologically expanded myeloid cells with immunosuppressiv …
Flow cytometric gating for spleen monocyte and DC subsets: differences in autoimmune NOD mice and with acute inflammation.
Dong MB, Rahman MJ, Tarbell KV. Dong MB, et al. J Immunol Methods. 2016 May;432:4-12. doi: 10.1016/j.jim.2015.08.015. Epub 2015 Sep 5. J Immunol Methods. 2016. PMID: 26344574 Free PMC article.
A simple but informative nomenclature of conventional and plasmacytoid dendritic cell subsets (cDC1, cDC2, pDC) and monocyte-derived populations incorporates these advances, but accurate subset identification is critical. ...Both acute inflammation, such as T …
A simple but informative nomenclature of conventional and plasmacytoid dendritic cell subsets (cDC1, cDC2, pDC) and monocyte-d …
Macrophages in intestinal homeostasis and inflammation.
Bain CC, Mowat AM. Bain CC, et al. Immunol Rev. 2014 Jul;260(1):102-17. doi: 10.1111/imr.12192. Immunol Rev. 2014. PMID: 24942685 Free PMC article. Review.
We also discuss the evidence that intestinal macrophages do not fit the current paradigm that tissue-resident macrophages are derived from embryonic precursors that self-renew in situ, but require constant replenishment by blood monocytes. We describe our recent work demon …
We also discuss the evidence that intestinal macrophages do not fit the current paradigm that tissue-resident macrophages are derived from e …
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