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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1920 1
1925 2
1929 1
1930 1
1931 1
1935 1
1938 2
1940 1
1941 1
1946 1
1947 1
1952 1
1953 1
1954 2
1955 1
1956 3
1958 3
1959 3
1960 3
1961 3
1962 2
1963 2
1964 2
1965 10
1966 9
1967 9
1968 10
1969 11
1970 19
1971 13
1972 16
1973 7
1974 10
1975 66
1976 62
1977 53
1978 52
1979 56
1980 62
1981 60
1982 69
1983 67
1984 99
1985 98
1986 85
1987 102
1988 74
1989 99
1990 104
1991 108
1992 115
1993 107
1994 117
1995 124
1996 125
1997 128
1998 128
1999 150
2000 115
2001 149
2002 167
2003 139
2004 157
2005 173
2006 190
2007 183
2008 198
2009 201
2010 210
2011 190
2012 225
2013 249
2014 229
2015 228
2016 237
2017 235
2018 254
2019 263
2020 277
2021 5
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6,274 results
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Two-component systems of Mycobacterium tuberculosis: structure-based approaches.
Tucker PA, Nowak E, Morth JP. Tucker PA, et al. Methods Enzymol. 2007;423:479-501. doi: 10.1016/S0076-6879(07)23023-X. Methods Enzymol. 2007. PMID: 17609147
Mycobacterium tuberculosis contains few two-component systems compared to many other bacteria, possibly because it has more serine/threonine signaling pathways. Even so, these two-component systems appear to play an important role in early intracellular survi …
Mycobacterium tuberculosis contains few two-component systems compared to many other bacteria, possibly because it has more serine/th …
A novel cholesterol/lipid delivery system for murine myeloma cell lines.
Chauhan G, Schmelzer AE. Chauhan G, et al. Biotechnol Prog. 2017 May;33(3):795-803. doi: 10.1002/btpr.2441. Epub 2017 Mar 7. Biotechnol Prog. 2017. PMID: 28187511
Traditionally, cholesterol is provided to these cells by supplementing cell culture media with a concentrated solution of cholesterol and other water insoluble components dissolved in 200-proof ethanol. However, the solubility of cholesterol in ethanol is limited, a …
Traditionally, cholesterol is provided to these cells by supplementing cell culture media with a concentrated solution of cholesterol and ot …
Sorting of lysosomal proteins.
Braulke T, Bonifacino JS. Braulke T, et al. Biochim Biophys Acta. 2009 Apr;1793(4):605-14. doi: 10.1016/j.bbamcr.2008.10.016. Epub 2008 Nov 12. Biochim Biophys Acta. 2009. PMID: 19046998 Free article. Review.
Lysosomes are composed of soluble and transmembrane proteins that are targeted to lysosomes in a signal-dependent manner. ...Other soluble enzymes and non-enzymatic proteins are transported to lysosomes in an M6P-independent manner mediated by alternative rec …
Lysosomes are composed of soluble and transmembrane proteins that are targeted to lysosomes in a signal-dependent manner. ...Other …
Therapeutic use of curcumin-encapsulated and curcumin-primed exosomes.
Oskouie MN, Aghili Moghaddam NS, Butler AE, Zamani P, Sahebkar A. Oskouie MN, et al. J Cell Physiol. 2019 Jun;234(6):8182-8191. doi: 10.1002/jcp.27615. Epub 2018 Oct 14. J Cell Physiol. 2019. PMID: 30317632 Review.
Curcumin, the bioactive pigment of turmeric which has polyphenolic-hydrophobic components, has been used for the treatment of a variety of diseases. ...Exosomes are capable of transferring lipids, proteins, RNAs and DNAs, both with and without direct cell-to-cell contact. …
Curcumin, the bioactive pigment of turmeric which has polyphenolic-hydrophobic components, has been used for the treatment of a varie …
Water-Soluble Vitamin E-Tocopheryl Phosphate.
Zingg JM. Zingg JM. Adv Food Nutr Res. 2018;83:311-363. doi: 10.1016/bs.afnr.2017.12.007. Epub 2018 Feb 12. Adv Food Nutr Res. 2018. PMID: 29477225 Review.
The hydrophobicity of vitamin E poses transport and metabolic challenges to regulate its bioavailability and to prevent its accumulation in lipid-rich tissues such as adipose tissue, brain, and liver. Water-soluble precursors of vitamin E (alpha-tocopherol, alphaT), such a …
The hydrophobicity of vitamin E poses transport and metabolic challenges to regulate its bioavailability and to prevent its accumulation in …
Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components.
Brown DM, Stone V, Findlay P, MacNee W, Donaldson K. Brown DM, et al. Occup Environ Med. 2000 Oct;57(10):685-91. doi: 10.1136/oem.57.10.685. Occup Environ Med. 2000. PMID: 10984341 Free PMC article.
OBJECTIVES: Particulate air pollution has been shown to cause adverse health effects, and the ultrafine particle component has been implicated. The aim of the present study was to investigate whether an ultrafine particle exerted its effects through transi
OBJECTIVES: Particulate air pollution has been shown to cause adverse health effects, and the ultrafine particle component has …
Intracellular Motility of Intermediate Filaments.
Leube RE, Moch M, Windoffer R. Leube RE, et al. Cold Spring Harb Perspect Biol. 2017 Jun 1;9(6):a021980. doi: 10.1101/cshperspect.a021980. Cold Spring Harb Perspect Biol. 2017. PMID: 28572456 Free PMC article. Review.
Motor protein-driven active transport, linkage to other cellular structures, diffusion of small soluble subunits, and intrinsic network elasticity all contribute to the motile behavior of IFs. ...Disturbances of IF motility are linked to diseases that are characterized by …
Motor protein-driven active transport, linkage to other cellular structures, diffusion of small soluble subunits, and intrinsic netwo …
A Solubility-based Separation of Group B Soyasaponins from the Whole Soybean Flour.
Katano H, Noba S, Taira S, Kambe T, Takahashi M. Katano H, et al. Anal Sci. 2019 Aug 10;35(8):935-937. doi: 10.2116/analsci.19N009. Epub 2019 Apr 5. Anal Sci. 2019. PMID: 30956262 Free article.
This note describes a simple and rapid method to separate specific soyasaponins, including the major and multi-functional bioactive species soyasaponin Bb, from the whole soybean flour. The method is based on the difference in solubility of the soyasaponins and other co
This note describes a simple and rapid method to separate specific soyasaponins, including the major and multi-functional bioactive species …
Electrospun amorphous solid dispersions of poorly water-soluble drugs: A review.
Yu DG, Li JJ, Williams GR, Zhao M. Yu DG, et al. J Control Release. 2018 Dec 28;292:91-110. doi: 10.1016/j.jconrel.2018.08.016. Epub 2018 Aug 14. J Control Release. 2018. PMID: 30118788 Review.
The development of oral dosage forms for poorly water-soluble active pharmaceutical ingredients (APIs) is a persistent challenge. ...These ASDs can be utilised to generate oral dosage forms for poorly water-soluble drugs, resulting in linear or multiple-phase releas …
The development of oral dosage forms for poorly water-soluble active pharmaceutical ingredients (APIs) is a persistent challenge. ... …
Unraveling inter-species differences in hagfish slime skein deployment.
Bernards MA Jr, Schorno S, McKenzie E, Winegard TM, Oke I, Plachetzki D, Fudge DS. Bernards MA Jr, et al. J Exp Biol. 2018 Dec 12;221(Pt 24):jeb176925. doi: 10.1242/jeb.176925. J Exp Biol. 2018. PMID: 30541919 Free article.
Hagfishes defend themselves from fish predators by producing defensive slime consisting of mucous and thread components that interact synergistically with seawater to pose a suffocation risk to their attackers. ...We found that Atlantic hagfish skeins are also held togethe …
Hagfishes defend themselves from fish predators by producing defensive slime consisting of mucous and thread components that interact …
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