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Influence of apple polyphenols on inflammatory gene expression.
Jung M, Triebel S, Anke T, Richling E, Erkel G. Jung M, et al. Mol Nutr Food Res. 2009 Oct;53(10):1263-80. doi: 10.1002/mnfr.200800575. Mol Nutr Food Res. 2009. PMID: 19764067
Besides the influence on proinflammatory gene expression, the effect on NF-kappaB-, IP-10-, IL-8-promoter-, STAT1-dependent signal transduction, and the relative protein levels of multiple released cytokines and chemokines were studied. ...The influence …
Besides the influence on proinflammatory gene expression, the effect on NF-kappaB-, IP-10-, IL-8-promoter-, STAT1-depen …
Cancer chemoprevention and nutriepigenetics: state of the art and future challenges.
Gerhauser C. Gerhauser C. Top Curr Chem. 2013;329:73-132. doi: 10.1007/128_2012_360. Top Curr Chem. 2013. PMID: 22955508 Review.
The term "epigenetics" refers to modifications in gene expression caused by heritable, but potentially reversible, changes in DNA methylation and chromatin structure. ...Over the past few years, nutriepigenetics - the influence of dietary components on mechan …
The term "epigenetics" refers to modifications in gene expression caused by heritable, but potentially reversible, changes in …
Reduction of colonic inflammation in HLA-B27 transgenic rats by feeding Marie Menard apples, rich in polyphenols.
Castagnini C, Luceri C, Toti S, Bigagli E, Caderni G, Femia AP, Giovannelli L, Lodovici M, Pitozzi V, Salvadori M, Messerini L, Martin R, Zoetendal EG, Gaj S, Eijssen L, Evelo CT, Renard CM, Baron A, Dolara P. Castagnini C, et al. Br J Nutr. 2009 Dec;102(11):1620-8. doi: 10.1017/S0007114509990936. Epub 2009 Jul 22. Br J Nutr. 2009. PMID: 19622193

After 3 months feeding, rats fed Marie Menard apples had reduced myeloperoxidase activity (3.6 (sem 0.3) v. 2.2 (sem 0.2) U/g tissue; P < 0.05) and reduced cyclo-oxygenase-2 (P < 0.05) and inducible NO synthase gene expression (P < 0.01) in the colon

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After 3 months feeding, rats fed Marie Menard apples had reduced myeloperoxidase activity (3.6 (sem 0.3) v. 2.2 (sem 0.2) U/g tissue; …