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2009 2
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Influence of apple polyphenols on inflammatory gene expression.
Jung M, Triebel S, Anke T, Richling E, Erkel G. Jung M, et al. Mol Nutr Food Res. 2009 Oct;53(10):1263-80. doi: 10.1002/mnfr.200800575. Mol Nutr Food Res. 2009. PMID: 19764067
Apples (Malus spp., Rosaceae) and products thereof contain high amounts of polyphenols which show diverse biological activities and may contribute to beneficial health effects, like protecting the intestine against inflammation initiated by chronic inflamm
Apples (Malus spp., Rosaceae) and products thereof contain high amounts of polyphenols which show diverse biological ac
Cancer chemoprevention and nutriepigenetics: state of the art and future challenges.
Gerhauser C. Gerhauser C. Top Curr Chem. 2013;329:73-132. doi: 10.1007/128_2012_360. Top Curr Chem. 2013. PMID: 22955508 Review.
The term "epigenetics" refers to modifications in gene expression caused by heritable, but potentially reversible, changes in DNA methylation and chromatin structure. Epigenetic alterations have been identified as promising new targets for cancer prevention strategi …
The term "epigenetics" refers to modifications in gene expression caused by heritable, but potentially reversible, changes in …
Reduction of colonic inflammation in HLA-B27 transgenic rats by feeding Marie Ménard apples, rich in polyphenols.
Castagnini C, Luceri C, Toti S, Bigagli E, Caderni G, Femia AP, Giovannelli L, Lodovici M, Pitozzi V, Salvadori M, Messerini L, Martin R, Zoetendal EG, Gaj S, Eijssen L, Evelo CT, Renard CM, Baron A, Dolara P. Castagnini C, et al. Br J Nutr. 2009 Dec;102(11):1620-8. doi: 10.1017/S0007114509990936. Epub 2009 Jul 22. Br J Nutr. 2009. PMID: 19622193

After 3 months feeding, rats fed Marie Menard apples had reduced myeloperoxidase activity (3.6 (sem 0.3) v. 2.2 (sem 0.2) U/g tissue; P < 0.05) and reduced cyclo-oxygenase-2 (P < 0.05) and inducible NO synthase gene expression (P < 0.01) in the colon

After 3 months feeding, rats fed Marie Menard apples had reduced myeloperoxidase activity (3.6 (sem 0.3) v. 2.2 (sem 0.2) U/g tissue; …