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Inhibition of TNF-alpha processing and TACE-mediated ectodomain shedding by ethanol.
Zhang Z, Cork J, Ye P, Lei D, Schwarzenberger PO, Summer WR, Shellito JE, Nelson S, Kolls JK. Zhang Z, et al. J Leukoc Biol. 2000 Jun;67(6):856-62. doi: 10.1002/jlb.67.6.856. J Leukoc Biol. 2000. PMID: 10857859
Acute EtOH-induced immunosuppression is partially due to suppression of tumor necrosis factor alpha (TNF-alpha) secretion. We investigated the mechanism of acute EtOH-induced TNF-alpha suppression in two monocytic cell lines …
Acute EtOH-induced immunosuppression is partially due to suppression of tumor necrosis factor alpha (TNF- …
Chronic ethanol enhances ectodomain shedding in T cells and monocytes.
Zhao XJ, Oliver P, Song K, Schurr J, Zhang Z, Kolls JK. Zhao XJ, et al. Alcohol Clin Exp Res. 2004 Sep;28(9):1399-407. doi: 10.1097/01.alc.0000139819.46514.06. Alcohol Clin Exp Res. 2004. PMID: 15365312
BACKGROUND: Chronic ethanol (EtOH) has been shown to augment tumor necrosis factor (TNF)-alpha production, and this has been associated with EtOH-induced liver injury. ...We hypothesized that chronic ethanol through oxidative stress activ …
BACKGROUND: Chronic ethanol (EtOH) has been shown to augment tumor necrosis factor (TNF)-alpha production …