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Year Number of Results
1995 2
1998 1
1999 1
2000 1
2005 1
2006 4
2007 5
2012 3
2013 2
2015 2
2017 1
2019 3
2020 2
2021 1
2022 1
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Extrinsic or Intrinsic Apoptosis by Curcumin and Light: Still a Mystery.
Laubach V, Kaufmann R, Bernd A, Kippenberger S, Zöller N. Laubach V, et al. Int J Mol Sci. 2019 Feb 19;20(4):905. doi: 10.3390/ijms20040905. Int J Mol Sci. 2019. PMID: 30791477 Free PMC article.
Curcumin-a rhizomal phytochemical from the plant Curcuma longa-is well known to inhibit cell proliferation and to induce apoptosis in a broad range of cell lines. ...To address this question, we investigated in three epithelial cell lines (HaCaT, A431, A549)
Curcumin-a rhizomal phytochemical from the plant Curcuma longa-is well known to inhibit cell proliferation and to induc
Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies.
Meresman GF, Götte M, Laschke MW. Meresman GF, et al. Hum Reprod Update. 2021 Feb 19;27(2):367-392. doi: 10.1093/humupd/dmaa039. Hum Reprod Update. 2021. PMID: 33124671 Review.
Their mechanisms of action include pleiotropic effects on known signalling effectors: oestrogen receptor-alpha, cyclooxygenase-2, interleukin-1 and -6, tumour necrosis factor-alpha, intercellular adhesion molecule-1, vascular endothelial growth …
Their mechanisms of action include pleiotropic effects on known signalling effectors: oestrogen receptor-alpha, cyclooxygenase-2, int …
Inhibition of tumor necrosis factor by curcumin, a phytochemical.
Chan MM. Chan MM. Biochem Pharmacol. 1995 May 26;49(11):1551-6. doi: 10.1016/0006-2952(95)00171-u. Biochem Pharmacol. 1995. PMID: 7786295
The pleiotropic cytokine tumor necrosis factor-alpha (TNF) induces the production of interleukin-1 beta (IL-1), and, together, they play significant roles in many acute and chronic inflammatory diseases. ...In addition, it demonstrates that curcumin
The pleiotropic cytokine tumor necrosis factor-alpha (TNF) induces the production of interleukin-1 beta (IL-1), …
Curcumin and obesity.
Bradford PG. Bradford PG. Biofactors. 2013 Jan-Feb;39(1):78-87. doi: 10.1002/biof.1074. Epub 2013 Jan 22. Biofactors. 2013. PMID: 23339049 Review.
In adipose tissue, curcumin inhibits macrophage infiltration and nuclear factor kappaB (NF-kappaB) activation induced by inflammatory agents. Curcumin reduces the expression of the potent proinflammatory adipokines tumor necrosis facto
In adipose tissue, curcumin inhibits macrophage infiltration and nuclear factor kappaB (NF-kappaB) activation induced b …
Curcumin induces apoptosis in tumor necrosis factor-alpha-treated HaCaT cells.
Sun J, Han J, Zhao Y, Zhu Q, Hu J. Sun J, et al. Int Immunopharmacol. 2012 Jun;13(2):170-4. doi: 10.1016/j.intimp.2012.03.025. Epub 2012 Apr 10. Int Immunopharmacol. 2012. PMID: 22498762
As expected, curcumin inhibited TNF-alpha-induced activation of NF-kappaB, including NF-kappaB-P65. Curcumin also inhibited the TNF-alpha-induced production of IL-6/IL-8 in HaCaT cells. ...
As expected, curcumin inhibited TNF-alpha-induced activation of NF-kappaB, including NF-kappaB-P65. Curcumin als …
In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties.
Chan MM, Huang HI, Fenton MR, Fong D. Chan MM, et al. Biochem Pharmacol. 1998 Jun 15;55(12):1955-62. doi: 10.1016/s0006-2952(98)00114-2. Biochem Pharmacol. 1998. PMID: 9714315
With respect to inflammation, in vitro, it inhibits the activation of free radical-activated transcription factors, such as nuclear factor kappaB (NFkappaB) and AP-1, and reduces the production of pro-inflammatory cytokines such as tumor necrosis fa
With respect to inflammation, in vitro, it inhibits the activation of free radical-activated transcription factors, such as nuclear …
Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals.
Chen SS, Michael A, Butler-Manuel SA. Chen SS, et al. Discov Med. 2012 Jan;13(68):7-17. Discov Med. 2012. PMID: 22284780 Free article. Review.
Based on widely published in vitro and mouse-model data, some anti-inflammatory phytochemicals appear to exhibit activity in modulating the tumor microenvironment. Specifically, apiegenin, baicalein, curcumin, EGCG, genistein, luteolin, oridonin, quercetin, a …
Based on widely published in vitro and mouse-model data, some anti-inflammatory phytochemicals appear to exhibit activity in modulati …
Curcumin ameliorates cardiac dysfunction induced by mechanical trauma.
Li X, Cao T, Ma S, Jing Z, Bi Y, Zhou J, Chen C, Yu D, Zhu L, Li S. Li X, et al. Eur J Pharmacol. 2017 Nov 5;814:73-80. doi: 10.1016/j.ejphar.2017.07.048. Epub 2017 Aug 10. Eur J Pharmacol. 2017. PMID: 28802718
Myocardial apoptosis was determined through terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining and caspase-3 activity assay. Tumor necrosis factor-alpha (TNF-alpha) and reactive oxygen species (ROS) generated by monocy …
Myocardial apoptosis was determined through terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining and caspase-3 acti …
Molecular Targets Implicated in the Antiparasitic and Anti-Inflammatory Activity of the Phytochemical Curcumin in Trichomoniasis.
Mallo N, Lamas J, Sueiro RA, Leiro JM. Mallo N, et al. Molecules. 2020 Nov 14;25(22):5321. doi: 10.3390/molecules25225321. Molecules. 2020. PMID: 33202696 Free PMC article.
We also investigated the role of CUR on pro-inflammatory responses induced in RAW 264.7 phagocytic cells by parasite proteinases on pro-inflammatory mediators such as the nitric oxide (NO), tumor necrosis factor alpha (TNFalpha), interleukin-1beta (IL- …
We also investigated the role of CUR on pro-inflammatory responses induced in RAW 264.7 phagocytic cells by parasite proteinases on pro-infl …
Inhibition effect of curcumin on TNF-α and MMP-13 expression induced by advanced glycation end products in chondrocytes.
Yang Q, Wu S, Mao X, Wang W, Tai H. Yang Q, et al. Pharmacology. 2013;91(1-2):77-85. doi: 10.1159/000345345. Epub 2012 Nov 26. Pharmacology. 2013. PMID: 23183190
AIMS: Accumulation of advanced glycation end products (AGEs) plays a pivotal role in the mechanism by which aging contributes to osteoarthritis (OA). In the present study, we examined the effect of curcumin, a pharmacologically safe phytochemical agent, on AGE-induc …
AIMS: Accumulation of advanced glycation end products (AGEs) plays a pivotal role in the mechanism by which aging contributes to osteoarthri …
26 results