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Curcumin and obesity.
Bradford PG. Bradford PG. Biofactors. 2013 Jan-Feb;39(1):78-87. doi: 10.1002/biof.1074. Epub 2013 Jan 22. Biofactors. 2013. PMID: 23339049 Review.
In adipose tissue, curcumin inhibits macrophage infiltration and nuclear factor kappaB (NF-kappaB) activation induced by inflammatory agents. Curcumin reduces the expression of the potent proinflammatory adipokines tumor necrosis facto
In adipose tissue, curcumin inhibits macrophage infiltration and nuclear factor kappaB (NF-kappaB) activation induced b …
Inhibition of tumor necrosis factor by curcumin, a phytochemical.
Chan MM. Chan MM. Biochem Pharmacol. 1995 May 26;49(11):1551-6. doi: 10.1016/0006-2952(95)00171-u. Biochem Pharmacol. 1995. PMID: 7786295
The pleiotropic cytokine tumor necrosis factor-alpha (TNF) induces the production of interleukin-1 beta (IL-1), and, together, they play significant roles in many acute and chronic inflammatory diseases. ...In addition, it demonstrates that curcumin
The pleiotropic cytokine tumor necrosis factor-alpha (TNF) induces the production of interleukin-1 beta (IL-1), …
Extrinsic or Intrinsic Apoptosis by Curcumin and Light: Still a Mystery.
Laubach V, Kaufmann R, Bernd A, Kippenberger S, Zöller N. Laubach V, et al. Int J Mol Sci. 2019 Feb 19;20(4):905. doi: 10.3390/ijms20040905. Int J Mol Sci. 2019. PMID: 30791477 Free PMC article.
Curcumin-a rhizomal phytochemical from the plant Curcuma longa-is well known to inhibit cell proliferation and to induce apoptosis in a broad range of cell lines. ...To address this question, we investigated in three epithelial cell lines (HaCaT, A431, A549)
Curcumin-a rhizomal phytochemical from the plant Curcuma longa-is well known to inhibit cell proliferation and to induc
Medicinal plants and their isolated phytochemicals for the management of chemotherapy-induced neuropathy: therapeutic targets and clinical perspective.
Oveissi V, Ram M, Bahramsoltani R, Ebrahimi F, Rahimi R, Naseri R, Belwal T, Devkota HP, Abbasabadi Z, Farzaei MH. Oveissi V, et al. Daru. 2019 Jun;27(1):389-406. doi: 10.1007/s40199-019-00255-6. Epub 2019 Mar 9. Daru. 2019. PMID: 30852764 Free PMC article. Review.
.), cinnamon (Cinnamomum cassia (L.) D. Don), and sweet flag (Acorus calamus L.) as well as phytochemicals like matrine, curcumin, and thioctic acid have demonstrated beneficial effects in animal models of CIPN via prevention of axonal degeneration, decrease in tota …
.), cinnamon (Cinnamomum cassia (L.) D. Don), and sweet flag (Acorus calamus L.) as well as phytochemicals like matrine, curcumin
Inhibition effect of curcumin on TNF-alpha and MMP-13 expression induced by advanced glycation end products in chondrocytes.
Yang Q, Wu S, Mao X, Wang W, Tai H. Yang Q, et al. Pharmacology. 2013;91(1-2):77-85. doi: 10.1159/000345345. Epub 2012 Nov 26. Pharmacology. 2013. PMID: 23183190
AIMS: Accumulation of advanced glycation end products (AGEs) plays a pivotal role in the mechanism by which aging contributes to osteoarthritis (OA). In the present study, we examined the effect of curcumin, a pharmacologically safe phytochemical agent, on AGE-induc …
AIMS: Accumulation of advanced glycation end products (AGEs) plays a pivotal role in the mechanism by which aging contributes to osteoarthri …
Curcumin induces apoptosis in tumor necrosis factor-alpha-treated HaCaT cells.
Sun J, Han J, Zhao Y, Zhu Q, Hu J. Sun J, et al. Int Immunopharmacol. 2012 Jun;13(2):170-4. doi: 10.1016/j.intimp.2012.03.025. Epub 2012 Apr 10. Int Immunopharmacol. 2012. PMID: 22498762
As expected, curcumin inhibited TNF-alpha-induced activation of NF-kappaB, including NF-kappaB-P65. Curcumin also inhibited the TNF-alpha-induced production of IL-6/IL-8 in HaCaT cells. ...
As expected, curcumin inhibited TNF-alpha-induced activation of NF-kappaB, including NF-kappaB-P65. Curcumin als …
Combination of curcumin and luteolin synergistically inhibits TNF-alpha-induced vascular inflammation in human vascular cells and mice.
Zhang L, Wang X, Zhang L, Virgous C, Si H. Zhang L, et al. J Nutr Biochem. 2019 Nov;73:108222. doi: 10.1016/j.jnutbio.2019.108222. Epub 2019 Aug 15. J Nutr Biochem. 2019. PMID: 31665675
The aims of this study were to investigate whether and how combined curcumin and luteolin synergistically inhibit tumor necrosis factor-alpha (TNF-alpha)-induced monocytes adhesion endothelium, a crucial step of the development of …
The aims of this study were to investigate whether and how combined curcumin and luteolin synergistically inhibit tumor
Curcumin improves neural function after spinal cord injury by the joint inhibition of the intracellular and extracellular components of glial scar.
Yuan J, Zou M, Xiang X, Zhu H, Chu W, Liu W, Chen F, Lin J. Yuan J, et al. J Surg Res. 2015 May 1;195(1):235-45. doi: 10.1016/j.jss.2014.12.055. Epub 2015 Jan 7. J Surg Res. 2015. PMID: 25661742
Using behavioral assessment, immunohistochemistry, real-time polymerase chain reaction, Western blotting, and enzyme-linked immunosorbent assay, we detected the intracellular and extracellular components of glial scar and related cytokines such as tumor necrosis
Using behavioral assessment, immunohistochemistry, real-time polymerase chain reaction, Western blotting, and enzyme-linked immunosorbent as …
In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties.
Chan MM, Huang HI, Fenton MR, Fong D. Chan MM, et al. Biochem Pharmacol. 1998 Jun 15;55(12):1955-62. doi: 10.1016/s0006-2952(98)00114-2. Biochem Pharmacol. 1998. PMID: 9714315
With respect to inflammation, in vitro, it inhibits the activation of free radical-activated transcription factors, such as nuclear factor kappaB (NFkappaB) and AP-1, and reduces the production of pro-inflammatory cytokines such as tumor necrosis fa
With respect to inflammation, in vitro, it inhibits the activation of free radical-activated transcription factors, such as nuclear …
The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma.
Siddiqui AM, Cui X, Wu R, Dong W, Zhou M, Hu M, Simms HH, Wang P. Siddiqui AM, et al. Crit Care Med. 2006 Jul;34(7):1874-82. doi: 10.1097/01.CCM.0000221921.71300.BF. Crit Care Med. 2006. PMID: 16715036
MEASUREMENTS AND MAIN RESULTS: Serum levels of liver enzymes (alanine aminotransferase and aspartate aminotransferase), lactate, albumin, and tumor necrosis factor (TNF)-alpha were measured at 20 hrs after CLP (i.e., late stage of sepsis). ...In cultur …
MEASUREMENTS AND MAIN RESULTS: Serum levels of liver enzymes (alanine aminotransferase and aspartate aminotransferase), lactate, albumin, an …
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