Interactions between ultrafine particles and transition metals in vivo and in vitro.
Toxicol Appl Pharmacol. 2002.
PMID: 12460745
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Interactions between ultrafine particles and transition metals in vivo and in vitro.
Toxicol Appl Pharmacol. 2002 Nov 1;184(3):172-9. doi: 10.1006/taap.2002.9501.
Toxicol Appl Pharmacol. 2002.
PMID: 12460745
In this study we aimed to investigate interactions between transition metal salts and a surrogate environmental particle-ultrafine carbon black (ufCB). ...In the rat lung ufCB induced a significant neutrophil influx and this inflammatory effect was potentiati …
In this study we aimed to investigate interactions between transition metal salts and a surrogate environmental particle-ul …
Endogenous doesn't always mean innocuous: a scoping review of iron toxicity by inhalation.
J Toxicol Environ Health B Crit Rev. 2020 Apr 2;23(3):107-136. doi: 10.1080/10937404.2020.1731896. Epub 2020 Feb 27.
J Toxicol Environ Health B Crit Rev. 2020.
PMID: 32106786
The remaining 87 papers were examined to summarize research dealing with in vitro, in vivo and epidemiological studies involving PM containing Fe or iron oxide following inhalation or instillation. ...Iron PM was found to induce inflammatory effects …
The remaining 87 papers were examined to summarize research dealing with in vitro, in vivo and epidemiological s …
Titanium dioxide and carbon black nanoparticles disrupt neuronal homeostasis via excessive activation of cellular prion protein signaling.
Part Fibre Toxicol. 2022 Jul 15;19(1):48. doi: 10.1186/s12989-022-00490-x.
Part Fibre Toxicol. 2022.
PMID: 35840975
Free PMC article.
This triggers PrP(C)-dependent activation of NADPH oxidase and subsequent production of reactive oxygen species (ROS) that alters redox equilibrium. Through PrP(C) interaction, NPs also promote the activation of 3-phosphoinositide-dependent kinase 1 (PDK1), which in turn p …
This triggers PrP(C)-dependent activation of NADPH oxidase and subsequent production of reactive oxygen species (ROS) that alters redox equi …
CD44 as a Central Integrator of Inflammation and Fibrosis: From Molecular Signaling to Environmental Modulation.
Int J Mol Sci. 2025 Sep 11;26(18):8870. doi: 10.3390/ijms26188870.
Int J Mol Sci. 2025.
PMID: 41009438
Free PMC article.
Review.
Its involvement in fibroblast differentiation into myofibroblasts, as well as induction of the invasive phenotype of these cells, shows striking analogies to the mechanisms of epithelial-to-mesenchymal transition (EMT) known from cancer progression. In this paper, we discu …
Its involvement in fibroblast differentiation into myofibroblasts, as well as induction of the invasive phenotype of these cells, shows stri …
Carbon black nanoparticles and cadmium co-exposure aggravates bronchial epithelial cells inflammation via autophagy-lysosome pathway.
Environ Res. 2024 Feb 1;242:117733. doi: 10.1016/j.envres.2023.117733. Epub 2023 Nov 22.
Environ Res. 2024.
PMID: 38000634
Adding 3 MA alleviated inflammatory responses, while applying the Baf-A1 inhibitor aggravated inflammation both in vitro and in vivo following CBNPs-Cd co-exposure. Factorial analysis showed no interaction between CBNPs and Cd in their effects o …
Adding 3 MA alleviated inflammatory responses, while applying the Baf-A1 inhibitor aggravated inflammation both in vitro and …
An Overview of Essential Microelements and Common Metallic Nanoparticles and Their Effects on Male Fertility.
Int J Environ Res Public Health. 2022 Sep 4;19(17):11066. doi: 10.3390/ijerph191711066.
Int J Environ Res Public Health. 2022.
PMID: 36078782
Free PMC article.
Review.
Numerous factors affect reproduction, including stress, diet, obesity, the use of stimulants, or exposure to toxins, along with heavy elements (lead, silver, cadmium, uranium, vanadium, mercury, arsenic). Metals, like other xenotoxins, can cause infertility through, …
Numerous factors affect reproduction, including stress, diet, obesity, the use of stimulants, or exposure to toxins, along with heavy ele …
Microstructures, mechanical, and biological properties of a novel Ti-6V-4V/zinc surface nanocomposite prepared by friction stir processing.
Int J Nanomedicine. 2018 Mar 28;13:1881-1898. doi: 10.2147/IJN.S154260. eCollection 2018.
Int J Nanomedicine. 2018.
PMID: 29636607
Free PMC article.
BACKGROUND: The interaction between the material and the organism affects the survival rate of the orthopedic or dental implant in vivo. ...The in vitro osteogenic differentiation of rat bone marrow stromal cells and rapid in vivo …
BACKGROUND: The interaction between the material and the organism affects the survival rate of the orthopedic or dental implant in …
Identification of serum proteins bound to industrial nanomaterials.
Toxicol Lett. 2012 Jan 5;208(1):41-50. doi: 10.1016/j.toxlet.2011.09.009. Epub 2011 Oct 4.
Toxicol Lett. 2012.
PMID: 22001751
We found that the NP surface chemistry had a great impact on the amount of bound protein with distinct ligands for each of the tested particles. The hydrophobic CB NPs bound much more protein than the hydrophilic metal oxide NPs. ...These studies will help to explain the d …
We found that the NP surface chemistry had a great impact on the amount of bound protein with distinct ligands for each of the tested par …
Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells.
Environ Health Perspect. 2005 Nov;113(11):1555-60. doi: 10.1289/ehp.8006.
Environ Health Perspect. 2005.
PMID: 16263511
Free PMC article.
High concentrations of airborne particles have been associated with increased pulmonary and cardiovascular mortality, with indications of a specific toxicologic role for ultrafine particles (UFPs; particles < 0.1 microm). ...Particle uptake in
…
High concentrations of airborne particles have been associated with increased pulmonary and cardiovascular mortality, with indication …
Oxidative interactions of synthetic lung epithelial lining fluid with metal-containing particulate matter.
Am J Physiol Lung Cell Mol Physiol. 2001 Oct;281(4):L807-15. doi: 10.1152/ajplung.2001.281.4.L807.
Am J Physiol Lung Cell Mol Physiol. 2001.
PMID: 11557584
Free article.
Epidemiology studies show association of morbidity and mortality with exposure to ambient air particulate matter (PM). Metals present in PM may catalyze oxidation of important lipids and proteins present in the lining of the respiratory tract. ...Residual oil …
Epidemiology studies show association of morbidity and mortality with exposure to ambient air particulate matter (PM). Meta …
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