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Interactions between ultrafine particles and transition metals in vivo and in vitro.
Wilson MR, Lightbody JH, Donaldson K, Sales J, Stone V. Wilson MR, et al. Toxicol Appl Pharmacol. 2002 Nov 1;184(3):172-9. doi: 10.1006/taap.2002.9501. Toxicol Appl Pharmacol. 2002. PMID: 12460745
In this study we aimed to investigate interactions between transition metal salts and a surrogate environmental particle-ultrafine carbon black (ufCB). ...In the rat lung ufCB induced a significant neutrophil influx and this inflammatory effect was potentiati …
In this study we aimed to investigate interactions between transition metal salts and a surrogate environmental particle-ul
Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells.
Geiser M, Rothen-Rutishauser B, Kapp N, Schürch S, Kreyling W, Schulz H, Semmler M, Im Hof V, Heyder J, Gehr P. Geiser M, et al. Environ Health Perspect. 2005 Nov;113(11):1555-60. doi: 10.1289/ehp.8006. Environ Health Perspect. 2005. PMID: 16263511 Free PMC article.

High concentrations of airborne particles have been associated with increased pulmonary and cardiovascular mortality, with indications of a specific toxicologic role for ultrafine particles (UFPs; particles < 0.1 microm). ...Particle uptake in vi

High concentrations of airborne particles have been associated with increased pulmonary and cardiovascular mortality, with indication …
Biological interactions and toxicity of nanomaterials in the respiratory tract and various approaches of aerosol generation for toxicity testing.
Creutzenberg O. Creutzenberg O. Arch Toxicol. 2012 Jul;86(7):1117-22. doi: 10.1007/s00204-012-0833-3. Epub 2012 Mar 15. Arch Toxicol. 2012. PMID: 22418596
Besides these effects also known to be induced by microsized particles, nanoparticles principally can translocate from the site of exposure to circulation and become systemically available. ...For example, in combination with partial dissolution, a strong lung response aft …
Besides these effects also known to be induced by microsized particles, nanoparticles principally can translocate from the site of ex …
Microstructures, mechanical, and biological properties of a novel Ti-6V-4V/zinc surface nanocomposite prepared by friction stir processing.
Zhu C, Lv Y, Qian C, Ding Z, Jiao T, Gu X, Lu E, Wang L, Zhang F. Zhu C, et al. Int J Nanomedicine. 2018 Mar 28;13:1881-1898. doi: 10.2147/IJN.S154260. eCollection 2018. Int J Nanomedicine. 2018. PMID: 29636607 Free PMC article.
BACKGROUND: The interaction between the material and the organism affects the survival rate of the orthopedic or dental implant in vivo. ...The in vitro osteogenic differentiation of rat bone marrow stromal cells and rapid in vivo osseointegration were …
BACKGROUND: The interaction between the material and the organism affects the survival rate of the orthopedic or dental implant in …
Biosafety of unmodified ultrafine gold particles (AuPs) upon interacting with human blood components before systemic use.
Naz F, Dinda AK, Saxena R, Koul V. Naz F, et al. Regul Toxicol Pharmacol. 2019 Oct;107:104405. doi: 10.1016/j.yrtph.2019.104405. Epub 2019 Jun 14. Regul Toxicol Pharmacol. 2019. PMID: 31207267
Ultrafine gold particles (AuPs) can be emerged as a good candidate in the field of drug delivery as well as in imaging applications. ...These findings further validate the utility of ultrafine AuPs for in-vivo applications....
Ultrafine gold particles (AuPs) can be emerged as a good candidate in the field of drug delivery as well as in imaging applica
Silver nanoparticles disrupt GDNF/Fyn kinase signaling in spermatogonial stem cells.
Braydich-Stolle LK, Lucas B, Schrand A, Murdock RC, Lee T, Schlager JJ, Hussain SM, Hofmann MC. Braydich-Stolle LK, et al. Toxicol Sci. 2010 Aug;116(2):577-89. doi: 10.1093/toxsci/kfq148. Epub 2010 May 20. Toxicol Sci. 2010. PMID: 20488942 Free PMC article.
Because glial cell line-derived neurotrophic factor (GDNF) is vital for SSC self-renewal in vitro and in vivo, we evaluated the effects of Ag-NPs on GDNF-mediated signaling in these cells. Although the nanoparticles did not reduce GDNF binding or Ret receptor activi …
Because glial cell line-derived neurotrophic factor (GDNF) is vital for SSC self-renewal in vitro and in vivo, we evaluated th …
Signal transduction pathways involved in particulate matter induced relaxation in rat aorta--spontaneous hypertensive versus Wistar Kyoto rats.
Bagate K, Meiring JJ, Gerlofs-Nijland ME, Cassee FR, Borm PJ. Bagate K, et al. Toxicol In Vitro. 2006 Feb;20(1):52-62. doi: 10.1016/j.tiv.2005.06.002. Epub 2005 Aug 1. Toxicol In Vitro. 2006. PMID: 16055302
Previously we reported that in vivo exposure to ambient particulate matter (PM) induces vasodilatation in rat aorta. ...CONCLUSION: Our data demonstrate that PM elicits a dose-dependent vasodilatation via activation of sGC in vascular smooth muscles. PM compo …
Previously we reported that in vivo exposure to ambient particulate matter (PM) induces vasodilatation in rat aorta. .. …
TiO2 nanoparticles induce endothelial cell activation in a pneumocyte-endothelial co-culture model.
Ramos-Godínez Mdel P, González-Gómez BE, Montiel-Dávalos A, López-Marure R, Alfaro-Moreno E. Ramos-Godínez Mdel P, et al. Toxicol In Vitro. 2013 Mar;27(2):774-81. doi: 10.1016/j.tiv.2012.12.010. Epub 2012 Dec 20. Toxicol In Vitro. 2013. PMID: 23261642
The effects of particulate matter (PM) on endothelial cells have been evaluated in vitro by exposing isolated endothelial cells to different types of PM. Although some of the findings from these experiments have been corroborated by in vivo studies, an …
The effects of particulate matter (PM) on endothelial cells have been evaluated in vitro by exposing isolated endotheli …
Endogenous doesn't always mean innocuous: a scoping review of iron toxicity by inhalation.
Morgan J, Bell R, Jones AL. Morgan J, et al. J Toxicol Environ Health B Crit Rev. 2020 Apr 2;23(3):107-136. doi: 10.1080/10937404.2020.1731896. Epub 2020 Feb 27. J Toxicol Environ Health B Crit Rev. 2020. PMID: 32106786 Review.
Ambient air pollution is a leading risk factor for the global burden of disease. One possible pathway of particulate matter (PM)-induced toxicity is through iron (Fe), the most abundant metal in the atmosphere. ...Our recommendations include an expansion of epidemio …
Ambient air pollution is a leading risk factor for the global burden of disease. One possible pathway of particulate matter (P …
Oxidative interactions of synthetic lung epithelial lining fluid with metal-containing particulate matter.
Sun G, Crissman K, Norwood J, Richards J, Slade R, Hatch GE. Sun G, et al. Am J Physiol Lung Cell Mol Physiol. 2001 Oct;281(4):L807-15. doi: 10.1152/ajplung.2001.281.4.L807. Am J Physiol Lung Cell Mol Physiol. 2001. PMID: 11557584 Free article.
Epidemiology studies show association of morbidity and mortality with exposure to ambient air particulate matter (PM). Metals present in PM may catalyze oxidation of important lipids and proteins present in the lining of the respiratory tract. ...Residual oil …
Epidemiology studies show association of morbidity and mortality with exposure to ambient air particulate matter (PM). Meta
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