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Showing results for Interleukin 10 is upregulated in lps tolerance
Your search for Interleukin 10 is upregulatedin LPS tolerance retrieved no results
Interleukin-10 is upregulated in LPS tolerance.
Frankenberger M, Pechumer H, Ziegler-Heitbrock HW. Frankenberger M, et al. J Inflamm. 1995;45(1):56-63. J Inflamm. 1995. PMID: 7583353
Lipopolysaccharide (LPS) stimulation of the human monocytic cell line Mono Mac 6 leads to rapid expression of both the pro-inflammatory cytokine tumor necrosis factor (TNF) and the anti-inflammatory cytokine interleukin-10 (IL-10). ...Although TNF has …
Lipopolysaccharide (LPS) stimulation of the human monocytic cell line Mono Mac 6 leads to rapid expression of both the pro-inflammato …
LPS enhances CTB-INSULIN induction of IDO1 and IL-10 synthesis in human dendritic cells.
Kim NS, Torrez T, Langridge W. Kim NS, et al. Cell Immunol. 2019 Apr;338:32-42. doi: 10.1016/j.cellimm.2019.03.003. Epub 2019 Mar 19. Cell Immunol. 2019. PMID: 30910218 Free PMC article.
While the extraction of LPS from bacterial generated CTB-INS may remove additional unknown factors that may contribute to the regulation of IDO1 levels, together, our experimental data suggest that LPS stimulates the ability of CTB-INS to induce IDO1 and IL- …
While the extraction of LPS from bacterial generated CTB-INS may remove additional unknown factors that may contribute to the regu …
Neutrophil chemotaxis and local expression of interleukin-10 in the tolerance of endotoxin-induced uveitis.
Mashimo H, Ohguro N, Nomura S, Hashida N, Nakai K, Tano Y. Mashimo H, et al. Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5450-7. doi: 10.1167/iovs.08-1878. Epub 2008 Aug 29. Invest Ophthalmol Vis Sci. 2008. PMID: 18757518
RESULTS: IL-10 gene expression in ICB was significantly upregulated for at least 1 month. Immunohistochemical examination indicated that dendritic cells in the ICB produced IL-10. Peripheral blood neutrophil chemotaxis in EIU-tolerant rats was inhibite …
RESULTS: IL-10 gene expression in ICB was significantly upregulated for at least 1 month. Immunohistochemical examination indi …
Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model.
van 't Veer C, van den Pangaart PS, van Zoelen MA, de Kruif M, Birjmohun RS, Stroes ES, de Vos AF, van der Poll T. van 't Veer C, et al. J Immunol. 2007 Nov 15;179(10):7110-20. doi: 10.4049/jimmunol.179.10.7110. J Immunol. 2007. PMID: 17982103 Free article. Clinical Trial.
Interestingly, a lower dose of LPS (1 ng/kg) induced LPS tolerance accompanied with IRAK-M up-regulation but without depletion of IRAK-1. ...In conclusion, LPS tolerance in human endotoxemia models is associated with IRAK-M up-regulati …
Interestingly, a lower dose of LPS (1 ng/kg) induced LPS tolerance accompanied with IRAK-M up-regulation but wit …
LPS response and endotoxin tolerance in Flt-3L-induced bone marrow-derived dendritic cells.
Patenaude J, D'Elia M, Côté-Maurais G, Bernier J. Patenaude J, et al. Cell Immunol. 2011;271(1):184-91. doi: 10.1016/j.cellimm.2011.06.020. Epub 2011 Jul 12. Cell Immunol. 2011. PMID: 21802073
In this study, we describe the phenotypical characteristics of an Flt-3L-dependent DC culture (FLDC) system following LPS stimulation, which induces an inflammatory response, and after a second LPS stimulation, which induces tolerance. ...In contrast, LPS …
In this study, we describe the phenotypical characteristics of an Flt-3L-dependent DC culture (FLDC) system following LPS stimulation …
IL-10 deficiency blocks the ability of LPS to regulate expression of tolerance-related molecules on dendritic cells.
Zhou F, Ciric B, Li H, Yan Y, Li K, Cullimore M, Lauretti E, Gonnella P, Zhang GX, Rostami A. Zhou F, et al. Eur J Immunol. 2012 Jun;42(6):1449-58. doi: 10.1002/eji.201141733. Epub 2012 May 23. Eur J Immunol. 2012. PMID: 22622800 Free PMC article.
Interleukin-10 (IL-10) is an anti-inflammatory cytokine that plays an important role in regulating the local inflammatory immune response, but regulatory mechanisms of this cytokine have not been fully elucidated. Here, we demonstrate that IL-10 …
Interleukin-10 (IL-10) is an anti-inflammatory cytokine that plays an important role in regulating the local inflammato …
Antigen-specific tolerance induced by IL-10 gene modified immature dendritic cells in experimental autoimmune myocarditis in rats.
Li WM, Liu W, Gao C, Zhou BG, Yang SS, Wang Z, Zhang RH, Gan RT, Kong YH, Li Y. Li WM, et al. Chin Med J (Engl). 2006 Oct 5;119(19):1646-52. Chin Med J (Engl). 2006. PMID: 17042978
IL-10 is a pleiotrophic immunomodulatory cytokine that functions at different levels of the immune response, so it has emerged as a promising therapeutic factor for the treatment of autoimmune/inflammatory diseases. ...CONCLUSIONS: IL-10 gene modified iDC ind …
IL-10 is a pleiotrophic immunomodulatory cytokine that functions at different levels of the immune response, so it has emerged …
Glycogen synthase kinase 3 is part of the molecular machinery regulating the adaptive response to LPS stimulation in microglial cells.
Ajmone-Cat MA, D'Urso MC, di Blasio G, Brignone MS, De Simone R, Minghetti L. Ajmone-Cat MA, et al. Brain Behav Immun. 2016 Jul;55:225-235. doi: 10.1016/j.bbi.2015.11.012. Epub 2015 Nov 22. Brain Behav Immun. 2016. PMID: 26593276
We found that lithium chloride (LiCl), a widely used GSK3 inhibitor and the mainstay treatment for bipolar disorder, reinforced the LPS adaptive response by enhancing both downregulation of pro-inflammatory genes (inducible nitric oxide synthase, interleukin 1β, …
We found that lithium chloride (LiCl), a widely used GSK3 inhibitor and the mainstay treatment for bipolar disorder, reinforced the LPS …
Mesenchymal Stem Cells Upregulate the Expression of PD-L1 But Not VDR in Dendritic Cells.
Moravej A, Karimi MH, Geramizadeh B, Azarpira N, Zarnani AH, Yaghobi R, Khosravi M, Kalani M, Gharesi-Fard B. Moravej A, et al. Immunol Invest. 2017 Jan;46(1):80-96. doi: 10.1080/08820139.2016.1225757. Epub 2016 Oct 13. Immunol Invest. 2017. PMID: 27736253
Given the importance of programmed cell death receptor-1 (PD-L1) and vitamin D receptor (VDR) expression in induction of tolerance in DCs, we were encouraged to investigate if one of the immunomodulatory functions of MSCs could be inducing upregulation of PD-L1 and …
Given the importance of programmed cell death receptor-1 (PD-L1) and vitamin D receptor (VDR) expression in induction of tolerance in …
MiR-146b Mediates Endotoxin Tolerance in Human Phagocytes.
Renzi TA, Rubino M, Gornati L, Garlanda C, Locati M, Curtale G. Renzi TA, et al. Mediators Inflamm. 2015;2015:145305. doi: 10.1155/2015/145305. Epub 2015 Sep 14. Mediators Inflamm. 2015. PMID: 26451077 Free PMC article.
A proper regulation of the innate immune response is fundamental to keep the immune system in check and avoid a chronic status of inflammation. ...However, their role in the context of endotoxin tolerance is just beginning to be explored. We here show …
A proper regulation of the innate immune response is fundamental to keep the immune system in check and avoid a chronic …
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