Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2000 2
2001 1
2002 1
2004 2
2005 2
2006 1
2008 1
2010 1
2011 1
2012 1
2013 1
2014 3
2015 3
2016 2
2017 2
2018 2
2019 2
2020 1
2023 1
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

29 results

Results by year

Citations

1 article found by citation matching

Search results

Filters applied: . Clear all
Page 1
Isoxanthohumol--Biologically active hop flavonoid.
Żołnierczyk AK, Mączka WK, Grabarczyk M, Wińska K, Woźniak E, Anioł M. Żołnierczyk AK, et al. Fitoterapia. 2015 Jun;103:71-82. doi: 10.1016/j.fitote.2015.03.007. Epub 2015 Mar 12. Fitoterapia. 2015. PMID: 25771121
Isoxanthohumol (IXN), apart from xanthohumol (XN) and 8-prenylnaringenin (8PN), is one of the most important prenylflavonoids found in hops. ...In addition, IXN shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV)
Isoxanthohumol (IXN), apart from xanthohumol (XN) and 8-prenylnaringenin (8PN), is one of the most important prenylflavonoids found i
Beer constituents as potential cancer chemopreventive agents.
Gerhäuser C. Gerhäuser C. Eur J Cancer. 2005 Sep;41(13):1941-54. doi: 10.1016/j.ejca.2005.04.012. Eur J Cancer. 2005. PMID: 15953717 Review.
Structural classes include simple phenols, benzoic- and cinnamic acid derivatives, coumarins, catechins, di-, tri- and oligomeric proanthocyanidins, (prenylated) chalcones and flavonoids as well as alpha- and iso-alpha-acids derived from hop. Compounds belonging to …
Structural classes include simple phenols, benzoic- and cinnamic acid derivatives, coumarins, catechins, di-, tri- and oligomeric proanthocy …
The Multiple Biological Targets of Hops and Bioactive Compounds.
Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM. Bolton JL, et al. Chem Res Toxicol. 2019 Feb 18;32(2):222-233. doi: 10.1021/acs.chemrestox.8b00345. Epub 2019 Jan 22. Chem Res Toxicol. 2019. PMID: 30608650 Free PMC article. Review.
Several hop constituents are responsible for distinct effects linked to multiple biological targets, including hormonal, metabolic, inflammatory, and epigenetic pathways. 8-PN is one of the most potent phytoestrogens and is responsible for hops' estrogenic activi
Several hop constituents are responsible for distinct effects linked to multiple biological targets, including hormonal, metab …
Hop-derived prenylflavonoid isoxanthohumol suppresses insulin resistance by changing the intestinal microbiota and suppressing chronic inflammation in high fat diet-fed mice.
Yamashita M, Fukizawa S, Nonaka Y. Yamashita M, et al. Eur Rev Med Pharmacol Sci. 2020 Feb;24(3):1537-1547. doi: 10.26355/eurrev_202002_20212. Eur Rev Med Pharmacol Sci. 2020. PMID: 32096203 Free article.
OBJECTIVE: To assess whether the hop-derived polyphenol isoxanthohumol suppresses insulin resistance by changing the intestinal microbiota. ...CONCLUSIONS: We found that isoxanthohumol can suppress HFD-induced insulin resistance by changing the intestinal mic …
OBJECTIVE: To assess whether the hop-derived polyphenol isoxanthohumol suppresses insulin resistance by changing the intestina …
Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
Stevens JF, Page JE. Stevens JF, et al. Phytochemistry. 2004 May;65(10):1317-30. doi: 10.1016/j.phytochem.2004.04.025. Phytochemistry. 2004. PMID: 15231405 Review.
Xanthohumol (3'-[3,3-dimethyl allyl]-2',4',4-trihydroxy-6'-methoxychalcone) is the principal prenylated flavonoid of the female inflorescences of the hop plant ('hops'), an ingredient of beer. ...These biological activities suggest that prenylflavonoid …
Xanthohumol (3'-[3,3-dimethyl allyl]-2',4',4-trihydroxy-6'-methoxychalcone) is the principal prenylated flavonoid of the female inflo …
Insect Antifeedant Potential of Xanthohumol, Isoxanthohumol, and Their Derivatives.
Stompor M, Dancewicz K, Gabryś B, Anioł M. Stompor M, et al. J Agric Food Chem. 2015 Aug 5;63(30):6749-56. doi: 10.1021/acs.jafc.5b02025. Epub 2015 Jul 27. J Agric Food Chem. 2015. PMID: 26176501
Xanthohumol (14) and isoxanthohumol (6) derived from hop (Humulus lupulus L., Cannabaceae) and selected chalcone and chromene derivatives, obtained by chemical synthesis, were studied for antifeedant activity against the peach-potato aphid (Myzus persicae [Su …
Xanthohumol (14) and isoxanthohumol (6) derived from hop (Humulus lupulus L., Cannabaceae) and selected chalcone and chromene …
The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10.
Seliger JM, Misuri L, Maser E, Hintzpeter J. Seliger JM, et al. J Enzyme Inhib Med Chem. 2018 Dec;33(1):607-614. doi: 10.1080/14756366.2018.1437728. J Enzyme Inhib Med Chem. 2018. PMID: 29532688 Free PMC article.
Xanthohumol (XN), a prenylated chalcone unique to hops (Humulus lupulus) and two derived prenylflavanones, isoxanthohumol (IX) and 8-prenylnaringenin (8-PN) gained increasing attention as potential anti-diabetic and cancer preventive compounds. ...The results of this study …
Xanthohumol (XN), a prenylated chalcone unique to hops (Humulus lupulus) and two derived prenylflavanones, isoxanthohumol (IX) and 8- …
Isoxanthohumol, a constituent of hop (Humulus lupulus L.), increases stress resistance in Caenorhabditis elegans dependent on the transcription factor DAF-16.
Büchter C, Havermann S, Koch K, Wätjen W. Büchter C, et al. Eur J Nutr. 2016 Feb;55(1):257-65. doi: 10.1007/s00394-015-0843-z. Epub 2015 Feb 3. Eur J Nutr. 2016. PMID: 25644181
PURPOSE: The flavanone isoxanthohumol (IX) has gained attention as antioxidative and chemopreventive agent, but the molecular mechanism of action remains unclear. ...CONCLUSION: IX or a bacterial metabolite of IX causes antioxidative effects as well as an increased stress …
PURPOSE: The flavanone isoxanthohumol (IX) has gained attention as antioxidative and chemopreventive agent, but the molecular mechani …
Synthesis and biological evaluation of 4'-O-acetyl-isoxanthohumol and its analogues as antioxidant and antiproliferative agents.
Stompor M, Świtalska M, Podgórski R, Uram Ł, Aebisher D, Wietrzyk J. Stompor M, et al. Acta Biochim Pol. 2017;64(3):577-583. doi: 10.18388/abp.2017_1608. Epub 2017 Aug 12. Acta Biochim Pol. 2017. PMID: 28803257 Free article.
Additionally, the activity of the acylated isoxanthohumols was higher than for 2. To the best of our knowledge this is the first report on bioactivity of monoacylated isoxanthohumol (3) and its ester derivatives as antiproliferative compounds in drug resistant cell …
Additionally, the activity of the acylated isoxanthohumols was higher than for 2. To the best of our knowledge this is the first repo …
Compounds derived from Humulus lupulus inhibit SARS-CoV-2 papain-like protease and virus replication.
Herzog AM, Göbel K, Marongiu L, Ruetalo N, Alonso MC, Leischner C, Busch C, Burkard M, Lauer UM, Geurink PP, Knobeloch KP, Schindler M, Fritz G, Venturelli S. Herzog AM, et al. Phytomedicine. 2024 Jan;123:155176. doi: 10.1016/j.phymed.2023.155176. Epub 2023 Oct 30. Phytomedicine. 2024. PMID: 37976697
Antiviral activity of hop compounds was assessed using the fluorescently labeled wildtype SARS-CoV-2 (icSARS-CoV-2-mNG) in Caco-2 host cells. RESULTS: Our in silico docking suggests that the purified hop compounds bind to the active site of SARS-CoV-2 …
Antiviral activity of hop compounds was assessed using the fluorescently labeled wildtype SARS-CoV-2 (icSARS-CoV-2-mNG) in Cac …
29 results