Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 3
1991 1
1992 6
1993 5
1994 8
1995 15
1996 6
1997 1
1998 5
1999 10
2000 15
2001 14
2002 19
2003 21
2004 28
2005 36
2006 36
2007 36
2008 38
2009 43
2010 50
2011 51
2012 63
2013 73
2014 65
2015 74
2016 62
2017 73
2018 90
2019 81
2020 63
2021 6
Text availability
Article attribute
Article type
Publication date

Search Results

967 results
Results by year
Filters applied: . Clear all
Page 1
Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma.
Zhu YX, Kortuem KM, Stewart AK. Zhu YX, et al. Leuk Lymphoma. 2013 Apr;54(4):683-7. doi: 10.3109/10428194.2012.728597. Epub 2012 Sep 28. Leuk Lymphoma. 2013. PMID: 22966948 Free PMC article. Review.
Although several mechanisms have been proposed to explain the activity of thalidomide, lenalidomide and pomalidomide in multiple myeloma (MM), including demonstrable anti-angiogenic, anti-proliferative and immunomodulatory effects, the precise cellular targets and molec
Although several mechanisms have been proposed to explain the activity of thalidomide, lenalidomide and pomalidomide in multiple myel …
Down-Regulation of miR-378d Increased Rab10 Expression to Help Clearance of Mycobacterium tuberculosis in Macrophages.
Zhu Y, Xiao Y, Kong D, Liu H, Chen X, Chen Y, Zhu T, Peng Y, Zhai W, Hu C, Chen H, Suo Lang SZ, Guo A, Niu J. Zhu Y, et al. Front Cell Infect Microbiol. 2020 Mar 17;10:108. doi: 10.3389/fcimb.2020.00108. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32257967 Free PMC article.
Mycobacterium tuberculosis (M. tb) can survive in the hostile microenvironment of cells by escaping host surveillance, but the molecular mechanisms are far from being fully understood. MicroRNAs might be involved in regulation of this intracellular process. . …
Mycobacterium tuberculosis (M. tb) can survive in the hostile microenvironment of cells by escaping host surveillance, but the molecular
Bioinformatics Analysis of Gene Expression Profiles for Risk Prediction in Patients with Septic Shock.
Hu Y, Cheng L, Zhong W, Chen M, Zhang Q. Hu Y, et al. Med Sci Monit. 2019 Dec 15;25:9563-9571. doi: 10.12659/MSM.918491. Med Sci Monit. 2019. PMID: 31838482 Free PMC article.
BACKGROUND Septic shock occurs when sepsis is associated with critically low blood pressure, and has a high mortality rate. This study aimed to undertake a bioinformatics analysis of gene expression profiles for risk prediction in septic shock. MATERIAL AND METHODS …
BACKGROUND Septic shock occurs when sepsis is associated with critically low blood pressure, and has a high mortality rate. This study aimed …
Involvement of NF-kappaB in the reversal of CYP3A down-regulation induced by sea buckthorn in BCG-induced rats.
Liu F, Wang T, Li X, Jia J, Lin Q, Xue Y. Liu F, et al. PLoS One. 2020 Sep 11;15(9):e0238810. doi: 10.1371/journal.pone.0238810. eCollection 2020. PLoS One. 2020. PMID: 32915856 Free PMC article.
Herein, we examined the regulatory effect of HRP on cytochrome P450 3A (CYP3A) in rats with immune liver injury, and explored the molecular mechanism of its hepatoprotective effect. Rat models of immunological liver injury were induced by intravenous injections of B …
Herein, we examined the regulatory effect of HRP on cytochrome P450 3A (CYP3A) in rats with immune liver injury, and explored the molecul
Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages.
Zhu JJ, Ramanathan P, Bishop EA, O'Donnell V, Gladue DP, Borca MV. Zhu JJ, et al. PLoS One. 2019 Nov 14;14(11):e0223955. doi: 10.1371/journal.pone.0223955. eCollection 2019. PLoS One. 2019. PMID: 31725732 Free PMC article.
Previous work has suggested that ASFV pathogenesis is primarily mediated by host cytokines produced by infected monocytes and macrophages. To better understand molecular mechanisms mediating virus pathogenesis and immune evasion, we used transcriptome analysis to id …
Previous work has suggested that ASFV pathogenesis is primarily mediated by host cytokines produced by infected monocytes and macrophages. T …
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Zhu Q, Yu T, Gan S, Wang Y, Pei Y, Zhao Q, Pei S, Hao S, Yuan J, Xu J, Hou F, Wu X, Peng C, Wu P, Qin J, Xiao Y. Zhu Q, et al. J Exp Med. 2020 Jul 6;217(7):e20192083. doi: 10.1084/jem.20192083. J Exp Med. 2020. PMID: 32324863 Free PMC article.
Ubiquitination is an essential mechanism in the control of antiviral immunity upon virus infection. ...Together, these findings establish TRIM24 as a critical positive regulator in controlling the activation of antiviral signaling and describe a previously unknown mecha
Ubiquitination is an essential mechanism in the control of antiviral immunity upon virus infection. ...Together, these findings estab …
Down-regulation of microRNA-375 regulates adipokines and inhibits inflammatory cytokines by targeting AdipoR2 in non-alcoholic fatty liver disease.
Lei L, Zhou C, Yang X, Li L. Lei L, et al. Clin Exp Pharmacol Physiol. 2018 Aug;45(8):819-831. doi: 10.1111/1440-1681.12940. Epub 2018 Apr 30. Clin Exp Pharmacol Physiol. 2018. PMID: 29569260
However, the specific function of miR-375 in the progression of NAFLD is still unclear and the molecular mechanisms underlying NAFLD have yet to be elucidated. Our study aimed at investigating the regulatory role of miR-375 in the molecular mechanisms
However, the specific function of miR-375 in the progression of NAFLD is still unclear and the molecular mechanisms underlying …
STAT1-mediated down-regulation of Bcl-2 expression is involved in IFN-gamma/TNF-alpha-induced apoptosis in NIT-1 cells.
Cao ZH, Zheng QY, Li GQ, Hu XB, Feng SL, Xu GL, Zhang KQ. Cao ZH, et al. PLoS One. 2015 Mar 26;10(3):e0120921. doi: 10.1371/journal.pone.0120921. eCollection 2015. PLoS One. 2015. PMID: 25811609 Free PMC article.
The enhancement in STAT-1 activity and a down-regulation in Bcl-2 expression was also observed in MIN6 cells, another murine beta-cell derived line, after cells exposure to the combination of TNF-alpha and IFN-gamma treatment. Knockdown of STAT-1 gene
The enhancement in STAT-1 activity and a down-regulation in Bcl-2 expression was also observed in MIN6 cells, another murine b …
Down-regulation of microRNA-21 reduces inflammation and podocyte apoptosis in diabetic nephropathy by relieving the repression of TIMP3 expression.
Chen X, Zhao L, Xing Y, Lin B. Chen X, et al. Biomed Pharmacother. 2018 Dec;108:7-14. doi: 10.1016/j.biopha.2018.09.007. Epub 2018 Sep 10. Biomed Pharmacother. 2018. PMID: 30212710 Free article.
BACKGROUND: Several miRNAs including miR-21 have emerged as important regulators in the development of diabetic nephropathy (DN). However, the molecular mechanism of miR-21 underlying DN pathogenesis remains to be further discussed. ...The relationship between TIMP3 …
BACKGROUND: Several miRNAs including miR-21 have emerged as important regulators in the development of diabetic nephropathy (DN). However, t …
MicroRNA-27a alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis through modulating TLR4/MyD88/NF-κB pathway.
Ju M, Liu B, He H, Gu Z, Liu Y, Su Y, Zhu D, Cang J, Luo Z. Ju M, et al. Cell Cycle. 2018;17(16):2001-2018. doi: 10.1080/15384101.2018.1509635. Epub 2018 Sep 19. Cell Cycle. 2018. PMID: 30231673 Free PMC article.
However, it remains unknown the biological function and regulatory mechanisms of miRNAs in the regulation of inflammation and apoptosis in ALI. The aim of this study is to identify and evaluate the potential role of miRNAs in ALI and reveal the underlying molecul
However, it remains unknown the biological function and regulatory mechanisms of miRNAs in the regulation of inflammation and …
967 results
You have reached the last page of results. A maximum of 10,000 results are available.
Jump to page