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Monocyte Subsets: Phenotypes and Function in Tuberculosis Infection.
Sampath P, Moideen K, Ranganathan UD, Bethunaickan R. Sampath P, et al. Front Immunol. 2018 Jul 30;9:1726. doi: 10.3389/fimmu.2018.01726. eCollection 2018. Front Immunol. 2018. PMID: 30105020 Free PMC article. Review.
Transcriptomic analyses of these subsets help to define their distinct functional properties. Tuberculosis (TB) is a disease instigated by the deadly pathogen Mycobacterium tuberculosis. ...In this review, we will focus on these monocyte subs
Transcriptomic analyses of these subsets help to define their distinct functional properties. Tuberculosis (TB) is a di …
Modulation of dendritic cell and monocyte subsets in tuberculosis-diabetes co-morbidity upon standard tuberculosis treatment.
Kumar NP, Moideen K, Sivakumar S, Menon PA, Viswanathan V, Kornfeld H, Babu S. Kumar NP, et al. Tuberculosis (Edinb). 2016 Dec;101:191-200. doi: 10.1016/j.tube.2016.10.004. Epub 2016 Oct 11. Tuberculosis (Edinb). 2016. PMID: 27865391 Free PMC article.
However, the effect of anti-TB treatment on the changes in dentritic cell (DC) and monocyte subset phenotype in TB-DM co-morbidity is not well understood. ...DC and monocyte subsets exhibit significant but borderline correlation with fasting blo …
However, the effect of anti-TB treatment on the changes in dentritic cell (DC) and monocyte subset phenotype in TB-DM c …
Infection rate and tissue localization of murine IL-12p40-producing monocyte-derived CD103(+) lung dendritic cells during pulmonary tuberculosis.
Leepiyasakulchai C, Taher C, Chuquimia OD, Mazurek J, Söderberg-Naucler C, Fernández C, Sköld M. Leepiyasakulchai C, et al. PLoS One. 2013 Jul 8;8(7):e69287. doi: 10.1371/journal.pone.0069287. Print 2013. PLoS One. 2013. PMID: 23861965 Free PMC article.
The tissue localization may influence the functional potential of αE-DC that accumulate in Mycobacterium tuberculosis-infected lungs. ...Our results support a model in which inflammatory monocytes are recruited into the M. tuberculosis-infected lung ti …
The tissue localization may influence the functional potential of αE-DC that accumulate in Mycobacterium tuberculosis-infected …
Profiling leucocyte subsets in tuberculosis-diabetes co-morbidity.
Kumar NP, Moideen K, Dhakshinraj SD, Banurekha VV, Nair D, Dolla C, Kumaran P, Babu S. Kumar NP, et al. Immunology. 2015 Oct;146(2):243-50. doi: 10.1111/imm.12496. Epub 2015 Jul 6. Immunology. 2015. PMID: 26095067 Free PMC article. Clinical Trial.
However, the phenotypic profile of leucocyte subsets at homeostasis in individuals with active or latent tuberculosis (LTB) with coincident diabetes is not known. ...Our data reveal that coincident diabetes alters the cellular subset distributio …
However, the phenotypic profile of leucocyte subsets at homeostasis in individuals with active or latent tuberculosi
In situ expression of cytokines and cellular phenotypes in the lungs of mice with slowly progressive primary tuberculosis.
Mustafa T, Phyu S, Nilsen R, Jonsson R, Bjune G. Mustafa T, et al. Scand J Immunol. 2000 Jun;51(6):548-56. doi: 10.1046/j.1365-3083.2000.00721.x. Scand J Immunol. 2000. PMID: 10849364 Free article.
The cellular phenotypes and the expression of cytokines were studied in the lungs of mice, using immunohistochemistry, during different phases of slowly progressive primary murine tuberculosis infection. ...The kinetics of T-lymphocyte subsets and the …
The cellular phenotypes and the expression of cytokines were studied in the lungs of mice, using immunohistochemistry, during differe …
Increased frequency and cell death of CD16+ monocytes with Mycobacterium tuberculosis infection.
Castaño D, García LF, Rojas M. Castaño D, et al. Tuberculosis (Edinb). 2011 Sep;91(5):348-60. doi: 10.1016/j.tube.2011.04.002. Epub 2011 May 28. Tuberculosis (Edinb). 2011. PMID: 21621464
Monocytes from tuberculosis patients exhibit functional and phenotypical alterations compared with healthy controls. To determine whether these discrepancies can be explained by changes in monocyte subsets, the expression of CD14 and CD16
Monocytes from tuberculosis patients exhibit functional and phenotypical alterations compared with healthy contr
CD163 levels, pro- and anti-inflammatory cytokine secretion of monocytes in children with pulmonary tuberculosis.
Aktas Cetin E, Pur Ozyigit L, Gelmez YM, Cakir E, Gedik AH, Deniz G. Aktas Cetin E, et al. Pediatr Pulmonol. 2017 May;52(5):675-683. doi: 10.1002/ppul.23617. Epub 2016 Sep 29. Pediatr Pulmonol. 2017. PMID: 27685837
OBJECTIVES: Childhood tuberculosis (TB) comprises an important part of the world's TB burden. Monocytes set up the early phase of infection because of innate immune responses. ...The aim of this study was to evaluate the monocyte phenotype
OBJECTIVES: Childhood tuberculosis (TB) comprises an important part of the world's TB burden. Monocytes set up the earl …
Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes.
Nebenzahl-Guimaraes H, van Laarhoven A, Farhat MR, Koeken VACM, Mandemakers JJ, Zomer A, van Hijum SAFT, Netea MG, Murray M, van Crevel R, van Soolingen D. Nebenzahl-Guimaraes H, et al. Am J Respir Crit Care Med. 2017 Jun 1;195(11):1519-1527. doi: 10.1164/rccm.201605-1042OC. Am J Respir Crit Care Med. 2017. PMID: 27997216 Free PMC article.
RATIONALE: Successful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacterium tuberculosis virulence factors. ...We then performed immunological experiments to measure in vitro cytokine production and neutrop …
RATIONALE: Successful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacteri …
Beyond macrophages: the diversity of mononuclear cells in tuberculosis.
Srivastava S, Ernst JD, Desvignes L. Srivastava S, et al. Immunol Rev. 2014 Nov;262(1):179-92. doi: 10.1111/imr.12217. Immunol Rev. 2014. PMID: 25319335 Free PMC article. Review.
Although M. tuberculosis has traditionally been thought to survive and replicate in macrophages, recent work in our laboratory and others has revealed that M. tuberculosis infects multiple subsets of mononuclear phagocytes in vivo and in vitro. In experimenta …
Although M. tuberculosis has traditionally been thought to survive and replicate in macrophages, recent work in our laboratory and ot …
Systemic Immunological changes in patients with distinct clinical outcomes during Mycobacterium tuberculosis infection.
Morais-Papini TF, Coelho-Dos-Reis JGA, Wendling APB, do Vale Antonelli LR, Wowk PF, Bonato VLD, Augusto VM, Elói-Santos S, Martins-Filho OA, Carneiro CM, Teixeira-Carvalho A. Morais-Papini TF, et al. Immunobiology. 2017 Nov;222(11):1014-1024. doi: 10.1016/j.imbio.2017.05.016. Epub 2017 May 26. Immunobiology. 2017. PMID: 28619539
MATERIALS AND METHODS: In this study, the phenotypic and functional profile of leukocytes of patients with active pulmonary tuberculosis (TB) and controls (CO) were fully scrutinized by immunophenotyping assays and in vitro short-term whole blood culture. ... …
MATERIALS AND METHODS: In this study, the phenotypic and functional profile of leukocytes of patients with active pulmonary …
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