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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 3
1976 3
1977 2
1978 4
1979 2
1980 8
1981 8
1982 13
1983 38
1984 24
1985 50
1986 50
1987 55
1988 64
1989 58
1990 73
1991 69
1992 78
1993 66
1994 77
1995 90
1996 74
1997 75
1998 111
1999 105
2000 129
2001 153
2002 154
2003 156
2004 151
2005 168
2006 153
2007 169
2008 159
2009 136
2010 153
2011 143
2012 144
2013 148
2014 158
2015 120
2016 142
2017 131
2018 127
2019 83
2020 28
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3,796 results
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Monocyte differentiation and antigen-presenting functions.
Jakubzick CV, Randolph GJ, Henson PM. Jakubzick CV, et al. Nat Rev Immunol. 2017 Jun;17(6):349-362. doi: 10.1038/nri.2017.28. Epub 2017 Apr 24. Nat Rev Immunol. 2017. PMID: 28436425 Review.
In this Review, we discuss the newer concepts underlying the maturation of emigrating monocytes into different classes of tissue macrophages, as well as their potential functions, as monocyte-derived cells, in the tissues. In addition, we consider the emergin …
In this Review, we discuss the newer concepts underlying the maturation of emigrating monocytes into different classes of tissue macr …
Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c(+)CD103(+) Monocytic Antigen-Presenting Cells in Tumors.
Sharma MD, Rodriguez PC, Koehn BH, Baban B, Cui Y, Guo G, Shimoda M, Pacholczyk R, Shi H, Lee EJ, Xu H, Johnson TS, He Y, Mergoub T, Venable C, Bronte V, Wolchok JD, Blazar BR, Munn DH. Sharma MD, et al. Immunity. 2018 Jan 16;48(1):91-106.e6. doi: 10.1016/j.immuni.2017.12.014. Immunity. 2018. PMID: 29343444 Free PMC article.
CD103(+) dendritic cells are critical for cross-presentation of tumor antigens. Here we have shown that during immunotherapy, large numbers of cells expressing CD103 arose in murine tumors via direct differentiation of Ly6c(+) monocytic precursors. The …
CD103(+) dendritic cells are critical for cross-presentation of tumor antigens. Here we have shown that during immunotherapy, …
Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation.
Döring M, Blees H, Koller N, Tischer-Zimmermann S, Müsken M, Henrich F, Becker J, Grabski E, Wang J, Janssen H, Zuschratter W, Neefjes J, Klawonn F, Eiz-Vesper B, Tampé R, Kalinke U. Döring M, et al. Blood Adv. 2019 Mar 26;3(6):839-850. doi: 10.1182/bloodadvances.2018027268. Blood Adv. 2019. PMID: 30867143 Free PMC article.
Dendritic cells (DCs) take up antigen in the periphery, migrate to secondary lymphoid organs, and present processed antigen fragments to adaptive immune cells and thus prime antigen-specific immunity. ...Collectively, these data are compatible with the …
Dendritic cells (DCs) take up antigen in the periphery, migrate to secondary lymphoid organs, and present processed antigen
Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells.
Van der Borght K, Scott CL, Martens L, Sichien D, Van Isterdael G, Nindl V, Saeys Y, Boon L, Ludewig B, Gillebert TC, Lambrecht BN. Van der Borght K, et al. Front Immunol. 2018 Nov 21;9:2714. doi: 10.3389/fimmu.2018.02714. eCollection 2018. Front Immunol. 2018. PMID: 30524444 Free PMC article.
Although T cell reactivity to cardiac self-antigen is common in the disease, it is unknown which antigen presenting cell (APC) triggers autoimmunity. ...Primarily cDC2s presented α-myosin to TCR-M cells and induced Th1/Th17 differentia
Although T cell reactivity to cardiac self-antigen is common in the disease, it is unknown which antigen presenting
Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation.
Germic N, Frangez Z, Yousefi S, Simon HU. Germic N, et al. Cell Death Differ. 2019 Mar;26(4):715-727. doi: 10.1038/s41418-019-0297-6. Epub 2019 Feb 8. Cell Death Differ. 2019. PMID: 30737475 Free PMC article. Review.
Autophagy is well equipped functionally to isolate microbial pathogens in autophagosomes and to carry out their clearance by dismemberment in the course of catabolic processes in the lysosome. Clearly, this is a non-metabolic function of autophagy that impacts stron …
Autophagy is well equipped functionally to isolate microbial pathogens in autophagosomes and to carry out their clearance by dismembe …
Generation of Human Monocyte-derived Dendritic Cells from Whole Blood.
Posch W, Lass-Flörl C, Wilflingseder D. Posch W, et al. J Vis Exp. 2016 Dec 24;(118):54968. doi: 10.3791/54968. J Vis Exp. 2016. PMID: 28060313 Free PMC article.
The major function of DCs is the induction of adaptive immunity in the lymph nodes by presenting antigens via MHC I and MHC II molecules to naïve T lymphocytes. ...For in vitro experiments or DC vaccination strategies, monocyte-derived DCs are routinel …
The major function of DCs is the induction of adaptive immunity in the lymph nodes by presenting antigens via MHC I and …
Heterogeneity, functional specialization and differentiation of monocyte-derived dendritic cells.
Chow KV, Sutherland RM, Zhan Y, Lew AM. Chow KV, et al. Immunol Cell Biol. 2017 Mar;95(3):244-251. doi: 10.1038/icb.2016.104. Epub 2016 Oct 17. Immunol Cell Biol. 2017. PMID: 27748730 Review.
Dendritic cells (DCs) are professional antigen-presenting cells that consist of functionally and phenotypically heterogeneous populations. Monocyte-derived DCs (moDCs) are a DC subset that have been attracting increasing interest owing to their potent …
Dendritic cells (DCs) are professional antigen-presenting cells that consist of functionally and phenotypically heterog …
Development of endocytosis, degradative activity, and antigen processing capacity during GM-CSF driven differentiation of murine bone marrow.
Olatunde AC, Abell LP, Landuyt AE, Hiltbold Schwartz E. Olatunde AC, et al. PLoS One. 2018 May 10;13(5):e0196591. doi: 10.1371/journal.pone.0196591. eCollection 2018. PLoS One. 2018. PMID: 29746488 Free PMC article.
CMP showed minimal uptake capacity with no detectable antigen processing and presenting function. The GMP population showed higher uptake capacity, modest proteolytic activity, and little T cell stimulatory function. In the monocyte popul …
CMP showed minimal uptake capacity with no detectable antigen processing and presenting function. The GMP population sh …
TLR2 stimulation impairs anti-inflammatory activity of M2-like macrophages, generating a chimeric M1/M2 phenotype.
Quero L, Hanser E, Manigold T, Tiaden AN, Kyburz D. Quero L, et al. Arthritis Res Ther. 2017 Nov 2;19(1):245. doi: 10.1186/s13075-017-1447-1. Arthritis Res Ther. 2017. PMID: 29096690 Free PMC article.
In the present study, we set out to investigate the impact of TLR stimulation on monocyte-derived M1 and M2 macrophage function and phenotype by mimicking the exposure to abundant TLR agonists as occurs in the context of RA. ...METHODS: Human monocytes
In the present study, we set out to investigate the impact of TLR stimulation on monocyte-derived M1 and M2 macrophage func
Inflammatory dendritic cells in mice and humans.
Segura E, Amigorena S. Segura E, et al. Trends Immunol. 2013 Sep;34(9):440-5. doi: 10.1016/j.it.2013.06.001. Epub 2013 Jul 4. Trends Immunol. 2013. PMID: 23831267 Free article. Review.
Dendritic cells (DCs) are a heterogeneous population of professional antigen-presenting cells. Several murine DC subsets have been identified that differ in their phenotype and functional properties. ...During inflammation, an additional DC subset has been de …
Dendritic cells (DCs) are a heterogeneous population of professional antigen-presenting cells. Several murine DC subsets have …
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