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Monocyte inflammatory profile is specific for individuals and associated with altered blood lipid levels.
Patel VK, Williams H, Li SCH, Fletcher JP, Medbury HJ. Patel VK, et al. Atherosclerosis. 2017 Aug;263:15-23. doi: 10.1016/j.atherosclerosis.2017.05.026. Epub 2017 May 22. Atherosclerosis. 2017. PMID: 28570862 Free article.
Here, we compared the inflammatory status of monocyte subsets and determined whether monocyte inflammatory changes are evident in individuals with a perturbed lipid profile. METHODS: Monocyte subset cytokine production, i
Here, we compared the inflammatory status of monocyte subsets and determined whether monocyte inflammatory chang …
Investigating endogenous immune-mediated monocyte memory in rheumatoid arthritis.
Marzeda AM, Schwenzer A, Didov BS, Woolcock K, Richard JB, Jennings LK, Julé AM, Yang N, Davidson S, Sansom S, Cribbs AP, Dendrou CA, Yue WW, Goodyear CS, Raza K, Midwood KS. Marzeda AM, et al. Ann Rheum Dis. 2025 Sep;84(9):1484-1500. doi: 10.1016/j.ard.2025.03.016. Epub 2025 May 10. Ann Rheum Dis. 2025. PMID: 40350372 Free article.
METHODS: Memory evoked by the extracellular matrix protein tenascin-C, a damage-associated, toll-like receptor 4 (TLR4) agonist, was compared to that induced by the pathogenic TLR4 agonist lipopolysaccharide (LPS) by transcriptomic and epigenetic profiling of mon
METHODS: Memory evoked by the extracellular matrix protein tenascin-C, a damage-associated, toll-like receptor 4 (TLR4) agonist, was …
A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis.
Cepika AM, Banchereau R, Segura E, Ohouo M, Cantarel B, Goller K, Cantrell V, Ruchaud E, Gatewood E, Nguyen P, Gu J, Anguiano E, Zurawski S, Baisch JM, Punaro M, Baldwin N, Obermoser G, Palucka K, Banchereau J, Amigorena S, Pascual V. Cepika AM, et al. J Exp Med. 2017 Nov 6;214(11):3449-3466. doi: 10.1084/jem.20170412. Epub 2017 Sep 21. J Exp Med. 2017. PMID: 28935693 Free PMC article.
The etiology of sporadic human chronic inflammatory diseases remains mostly unknown. To fill this gap, we developed a strategy that simultaneously integrates blood leukocyte responses to innate stimuli at the transcriptional, cellular, and secreted protein levels
The etiology of sporadic human chronic inflammatory diseases remains mostly unknown. To fill this gap, we developed a strategy that s …
Systemic hematologic, metabolic, and inflammatory dysregulation in liver cirrhosis and hepatocellular carcinoma: diagnostic utility of novel indices in an Egyptian cohort.
Sherief DE, Shehata HH, Nosair N, Othman AAA, Saleh MW, Sadaka E, Elgamal R. Sherief DE, et al. BMC Gastroenterol. 2026 Apr 13;26(1):229. doi: 10.1186/s12876-026-04752-2. BMC Gastroenterol. 2026. PMID: 41975283 Free PMC article.
This study aimed to delineate the comprehensive clinical, hematologic, metabolic, and inflammatory profiles distinguishing Egyptian patients with HCC and liver cirrhosis from healthy controls, and to evaluate the diagnostic and discriminative utility of novel system …
This study aimed to delineate the comprehensive clinical, hematologic, metabolic, and inflammatory profiles distinguishing Egy …
Acute effects of different degrees of ultra-endurance exercise on systemic inflammatory responses.
Comassi M, Vitolo E, Pratali L, Del Turco S, Dellanoce C, Rossi C, Santini E, Solini A. Comassi M, et al. Intern Med J. 2015 Jan;45(1):74-9. doi: 10.1111/imj.12625. Intern Med J. 2015. PMID: 25371101
AIM: To compare the short-term effect of two different ultra-endurance competitions on the inflammatory profile in male triathletes. METHODS: We studied 14 Ironman (IR) and 13 Half Ironman (HIR) before and after their own specific race. We assessed body compo …
AIM: To compare the short-term effect of two different ultra-endurance competitions on the inflammatory profile in male triath …