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Monocyte subpopulations and cardiovascular risk in chronic kidney disease.
Heine GH, Ortiz A, Massy ZA, Lindholm B, Wiecek A, Martínez-Castelao A, Covic A, Goldsmith D, Süleymanlar G, London GM, Parati G, Sicari R, Zoccali C, Fliser D; European Renal and Cardiovascular Medicine (EURECA‑m) working group of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA). Heine GH, et al. Nat Rev Nephrol. 2012 Mar 13;8(6):362-9. doi: 10.1038/nrneph.2012.41. Nat Rev Nephrol. 2012. PMID: 22410492 Review.
Chronic microinflammation and its cellular hallmark, monocyte activation, contribute substantially to the tremendous burden of cardiovascular disease (CVD) in patients with chronic kidney diseases (CKD). Monocyte heterogeneity is w
Chronic microinflammation and its cellular hallmark, monocyte activation, contribute substantially to the tremendous burden of
36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016.
Bateman RM, Sharpe MD, Jagger JE, Ellis CG, Solé-Violán J, López-Rodríguez M, Herrera-Ramos E, Ruíz-Hernández J, Borderías L, Horcajada J, González-Quevedo N, Rajas O, Briones M, Rodríguez de Castro F, Rodríguez Gallego C, Esen F, Orhun G, Ergin Ozcan P, Senturk E, Ugur Yilmaz C, Orhan N, Arican N, Kaya M, Kucukerden M, Giris M, Akcan U, Bilgic Gazioglu S, Tuzun E, Riff R, Naamani O, Douvdevani A, Takegawa R, Yoshida H, Hirose T, Yamamoto N, Hagiya H, Ojima M, Akeda Y, Tasaki O, Tomono K, Shimazu T, Ono S, Kubo T, Suda S, Ueno T, Ikeda T, Hirose T, Ogura H, Takahashi H, Ojima M, Kang J, Nakamura Y, Kojima T, Shimazu T, Ikeda T, Suda S, Izutani Y, Ueno T, Ono S, Taniguchi T, O M, Dinter C, Lotz J, Eilers B, Wissmann C, Lott R, Meili MM, Schuetz PS, Hawa H, Sharshir M, Aburageila M, Salahuddin N, Chantziara V, Georgiou S, Tsimogianni A, Alexandropoulos P, Vassi A, Lagiou F, Valta M, Micha G, Chinou E, Michaloudis G, Kodaira A, Ikeda T, Ono S, Ueno T, Suda S, Izutani Y, Imaizumi H, De la Torre-Prados MV, Garcia-De la Torre A, Enguix-Armada A, Puerto-Morlan A, Perez-Valero V, Garcia-Alcantara A, Bolton N, Dudziak J, Bonney S, Tridente A, Nee P, Nicolaes G, Wiewel M, Schultz M, Wildhagen K, Horn J, Schrijver R, Van der Poll T, Reutelingsperger C, Pillai S, Davies G, Mills G, Aubrey R, Morris K, Williams P, Evans P, Gayat EG, Struck J, Cariou A, Deye N, Guidet B, Jabert S, Launay J, Legrand M, Léone M, Resche-Rigon M, Vicaut E, Vieillard-Baron A, Mebazaa A, Arnold R, Capan M, Linder A, Akesson P, Popescu M, Tomescu D, Sprung CL, Calderon Morales R, Munteanu G, Orenbuch-Harroch E, Levin P, Kasdan H, Reiter A, Volker T, Himmel Y, Cohen Y, Meissonnier J, Girard L, Rebeaud F, Herrmann I, Delwarde B, Peronnet E, Cerrato E, Venet F, Lepape A, Rimmelé T, Monneret G, Textoris J, Beloborodova N, Moroz V, Osipov A, Bedova A, Sarshor Y, Pautova A, Sergeev A, Chernevskaya E, Odermatt J, Bolliger R, Hersberger L, Ottiger M, Christ-Crain M, Mueller B, Schuetz P, Sharma NK, Tashima AK, Brunialti MK, Machado FR, Assuncao M, Rigato O, Salomao R, Cajander SC, Rasmussen G, Tina E, Söderquist B, Källman J, Strålin K, Lange AL, Sundén-Cullberg JS, Magnuson AM, Hultgren OH, Davies G, Pillai S, Mills G, Aubrey R, Morris K, Williams P, Evans P, Pillai S, Davies G, Mills G, Aubrey R, Morris K, Williams P, Evans P, Pillai S, Davies G, Mills G, Aubrey R, Morris K, Williams P, Evans P, Van der Geest P, Mohseni M, Linssen J, De Jonge R, Duran S, Groeneveld J, Miller R III, Lopansri BK, McHugh LC, Seldon A, Burke JP, Johnston J, Reece-Anthony R, Bond A, Molokhia A, Mcgrath C, Nsutebu E, Bank Pedersen P, Pilsgaard Henriksen D, Mikkelsen S, Touborg Lassen A, Tincu R, Cobilinschi C, Tomescu D, Ghiorghiu Z, Macovei R, Wiewel MA, Harmon MB, Van Vught LA, Scicluna BP, Hoogendijk AJ, Horn J, Zwinderman AH, Cremer OL, Bonten MJ, Schultz MJ, Van der Poll T, Juffermans NP, Wiersinga WJ, Eren G, Tekdos Y, Dogan M, Acicbe O, Kaya E, Hergunsel O, Alsolamy S, Ghamdi G, Alswaidan L, Alharbi S, 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Titeca D, Brazier F, Riviere A, Joris M, Soupison T, De Cagny B, El Dash S, Slama M, Remmington, Fischer A, Squire S, Boichat M, Honzawa H, Yasuda H, Adati T, Suzaki S, Horibe M, Sasaki M, Sanui M, Marinho R, Daniel J, Miranda H, Marinho A, Milinis K, Cooper M, Williams GR, McCarron E, Simants S, Patanwala I, Welters I, Su Y, Fernández Villanueva J, Fernández Garda R, López Lago A, Rodríguez Ruíz E, Hernández Vaquero R, Tomé Martínez de Rituerto S, Varo Pérez E, Lefel N, Schaap F, Bergmans D, Olde Damink S, Van de Poll M, Tizard K, Lister C, Poole L, Ringaitiene D, Gineityte D, Vicka V, Norkiene I, Sipylaite J, O’Loughlin A, Maraj V, Dowling J, Velasco MB, Dalcomune DM, Dias EB, Fernandes SL, Oshima T, Graf S, Heidegger C, Genton L, Karsegard V, Dupertuis Y, Pichard C, Friedli N, Stanga Z, Mueller B, Schuetz P, Vandersteen L, Stessel B, Evers S, Van Assche A, Jamaer L, Dubois J, Marinho R, Castro H, Moura J, Valente J, Martins P, Casteloes P, Magalhaes C, Cabral S, Santos M, Oliveira 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Bateman RM, et al. Crit Care. 2016 Apr 20;20(Suppl 2):94. doi: 10.1186/s13054-016-1208-6. Crit Care. 2016. PMID: 27885969 Free PMC article.
Trifi, S. Abdellatif, F. Daly, R. Nasri, S. Ben Lakhal P101 - Septic shock is an independent risk factor for colistin-induced severe acute kidney injury: a retrospective cohort study B. ...Cooper, G. R. Williams, E. McCarron, S. Simants, I. Pata …
Trifi, S. Abdellatif, F. Daly, R. Nasri, S. Ben Lakhal P101 - Septic shock is an independent risk factor for colistin-i …
Expression of purinergic P2X(7) receptors in subpopulations of peripheral blood mononuclear cells in early-stage of chronic kidney disease.
Lajdova I, Oksa A, Horvathova M, Spustova V. Lajdova I, et al. J Physiol Pharmacol. 2017 Oct;68(5):779-785. J Physiol Pharmacol. 2017. PMID: 29375053 Free article.
Chronic kidney disease (CKD) is known as a state of chronic low-grade inflammation, enhancing cardiovascular risk and immunodeficiency. ...In conclusion, the increased P2X(7) receptors expression in monocytes, the monocyte c
Chronic kidney disease (CKD) is known as a state of chronic low-grade inflammation, enhancing cardiovascular
NLRP3 Inflammasome Activation in Hemodialysis and Hypertensive Patients with Intact Kidney Function.
Ulrich C, Wildgrube S, Fiedler R, Seibert E, Kneser L, Fick S, Schäfer C, Markau S, Trojanowicz B, Girndt M. Ulrich C, et al. Toxins (Basel). 2020 Oct 26;12(11):675. doi: 10.3390/toxins12110675. Toxins (Basel). 2020. PMID: 33114648 Free PMC article.
Therefore, we investigated in an observational pilot study whether IL-1beta secretion and inflammatory cell death (pyroptosis) are different in HD and hypertensive patients with intact kidney function. Twenty HD patients were age-, gender-, and diabetes-mellitus-matched to …
Therefore, we investigated in an observational pilot study whether IL-1beta secretion and inflammatory cell death (pyroptosis) are different …
Association of chronic inflammation and accelerated atherosclerosis among an indigenous black population with chronic kidney disease.
Hassan MO, Dix-Peek T, Duarte R, Dickens C, Naidoo S, Vachiat A, Grinter S, Manga P, Naicker S. Hassan MO, et al. PLoS One. 2020 Jul 10;15(7):e0232741. doi: 10.1371/journal.pone.0232741. eCollection 2020. PLoS One. 2020. PMID: 32649699 Free PMC article.
INTRODUCTION: Inflammation plays a major role in the development of atherosclerosis and cardiovascular morbidity and mortality in chronic kidney disease (CKD) patients. ...MATERIALS AND METHODS: Endotoxin, lipopolysaccharide binding protein (LBP), seru …
INTRODUCTION: Inflammation plays a major role in the development of atherosclerosis and cardiovascular morbidity and mortality in …
Chronic Kidney Disease Severity Is Associated With Selective Expansion of a Distinctive Intermediate Monocyte Subpopulation.
Naicker SD, Cormican S, Griffin TP, Maretto S, Martin WP, Ferguson JP, Cotter D, Connaughton EP, Dennedy MC, Griffin MD. Naicker SD, et al. Front Immunol. 2018 Dec 6;9:2845. doi: 10.3389/fimmu.2018.02845. eCollection 2018. Front Immunol. 2018. PMID: 30619252 Free PMC article. Clinical Trial.
Chronic kidney disease (CKD) affects 11-13% of the world's population and greatly increases risk of atherosclerotic cardiovascular disease (ASCVD) and death. ...Together, our data confirm neutrophil and monocyte subse
Chronic kidney disease (CKD) affects 11-13% of the world's population and greatly increases risk o
Transcriptome analysis in patients with chronic kidney disease on hemodialysis disclosing a key role for CD16+CX3CR1+ monocytes.
Schepers E, Houthuys E, Dhondt A, De Meyer G, Neirynck N, Bernaert P, Van den Bergh R, Brouckaert P, Vanholder R, Glorieux G. Schepers E, et al. PLoS One. 2015 Apr 1;10(4):e0121750. doi: 10.1371/journal.pone.0121750. eCollection 2015. PLoS One. 2015. PMID: 25830914 Free PMC article.
The risk for cardiovascular morbidity and mortality is increased in chronic kidney disease; in this process micro-inflammation plays an essential role. ...In this pilot study transcriptome analysis of peripheral blood monocytes was used t …
The risk for cardiovascular morbidity and mortality is increased in chronic kidney disease; in this proce …
Kidney inflammaging is promoted by CCR2(+) macrophages and tissue-derived micro-environmental factors.
Lefèvre L, Iacovoni JS, Martini H, Bellière J, Maggiorani D, Dutaur M, Marsal DJ, Decaunes P, Pizzinat N, Mialet-Perez J, Cussac D, Parini A, Douin-Echinard V. Lefèvre L, et al. Cell Mol Life Sci. 2021 Apr;78(7):3485-3501. doi: 10.1007/s00018-020-03719-0. Epub 2020 Dec 12. Cell Mol Life Sci. 2021. PMID: 33313981 Free PMC article.
In the context of ageing, increased frequency of CD73(+) kMSC subpopulations could provide additional niche factors to newly recruited monocytes favoring a positive regulatory loop in response to local inflammation. Interfering with such partnership during ag …
In the context of ageing, increased frequency of CD73(+) kMSC subpopulations could provide additional niche factors to newly r …
Novel Immune Cell Subsets Exhibit Different Associations With Vascular Outcomes in Chronic Kidney Disease Patients-Identifying Potential Biomarkers.
Rodríguez-Carrio J, Carrillo-López N, Ulloa C, Martín-Carro B, Rodríguez-Suárez C, Naves-Díaz M, Sánchez-Álvarez E, Rodríguez-García M, Arcidiacono MV, Fernández-Mariño B, Cannata-Andía JB, Suárez A, Dusso AS. Rodríguez-Carrio J, et al. Front Med (Lausanne). 2021 May 25;8:618286. doi: 10.3389/fmed.2021.618286. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34113627 Free PMC article.

Results: In CKD5-PD, decreased Tang levels (p < 0.001) were unrelated to clinical features or traditional cardiovascular (CV) risk factors but correlated negatively with troponin T levels (r = -0.550, p = 0.003). ...Conclusions: Novel T cell and monocyt

Results: In CKD5-PD, decreased Tang levels (p < 0.001) were unrelated to clinical features or traditional cardiovascular (CV) r

Modulation of endogenous antioxidant defense and the progression of kidney disease in multi-heritage groups of patients with type 2 diabetes: PRospective EValuation of Early Nephropathy and its Treatment (PREVENT).
Earle KA, Zitouni K, Pepe J, Karaflou M, Godbold J Jr. Earle KA, et al. J Transl Med. 2016 Aug 4;14(1):234. doi: 10.1186/s12967-016-0975-9. J Transl Med. 2016. PMID: 27492324 Free PMC article.
BACKGROUND: Diabetes is the western world's leading cause of end-stage renal disease. Glucose-dependent, oxidative stress is linked to the development of renal inflammation and sclerosis, which, in animal models of diabetes, can be prevented by anti-ox …
BACKGROUND: Diabetes is the western world's leading cause of end-stage renal disease. Glucose-dependent, oxidative stre …
13 results