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1993 2
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2005 6
2006 6
2007 4
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2011 13
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2019 8
2020 12
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Monocytes and macrophages in abdominal aortic aneurysm.
Raffort J, Lareyre F, Clément M, Hassen-Khodja R, Chinetti G, Mallat Z. Raffort J, et al. Nat Rev Cardiol. 2017 Aug;14(8):457-471. doi: 10.1038/nrcardio.2017.52. Epub 2017 Apr 13. Nat Rev Cardiol. 2017. PMID: 28406184 Review.
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high morbidity, and high mortality in the event of aortic rupture. ...In this Review, we focus specifically on the involvement of monocytes and macrophages, sum
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high morbidity, and high mortality in the
Monocytes, Macrophages and Other Inflammatory Mediators of Abdominal Aortic Aneurysm.
Potteaux S, Tedgui A. Potteaux S, et al. Curr Pharm Des. 2015;21(28):4007-15. doi: 10.2174/1381612821666150826093855. Curr Pharm Des. 2015. PMID: 26306839 Review.
Macrophages early invade the forming abdominal aortic aneurysm (AAA) and greatly contribute to its pathogenesis. Recent findings have shown that Ly-6C(high) and Ly-6C(low) monocytes are rapidly mobilized from the splenic reservoir in response to
Macrophages early invade the forming abdominal aortic aneurysm (AAA) and greatly contribute to its pathogenesis.
Involvement of macrophage-derived exosomes in abdominal aortic aneurysms development.
Wang Y, Jia L, Xie Y, Cai Z, Liu Z, Shen J, Lu Y, Wang Y, Su S, Ma Y, Xiang M. Wang Y, et al. Atherosclerosis. 2019 Oct;289:64-72. doi: 10.1016/j.atherosclerosis.2019.08.016. Epub 2019 Aug 25. Atherosclerosis. 2019. PMID: 31479773
BACKGROUND AND AIMS: Abdominal aortic aneurysm (AAA) is characterized by infiltration of inflammatory cells, extracellular matrix (ECM) degradation, and dysfunction of vascular smooth muscle cells (VSMCs). ...To explore the underlying mechanisms, the human …
BACKGROUND AND AIMS: Abdominal aortic aneurysm (AAA) is characterized by infiltration of inflammatory cells, extracellu …
Epigenetic Mechanisms in Monocytes/Macrophages Regulate Inflammation in Cardiometabolic and Vascular Disease.
Davis FM, Gallagher KA. Davis FM, et al. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):623-634. doi: 10.1161/ATVBAHA.118.312135. Arterioscler Thromb Vasc Biol. 2019. PMID: 30760015 Free PMC article. Review.
In this regard, monocytes/macrophages are key players in the development of a chronic inflammatory state. Over the past decade, epigenetic modifications, such as DNA methylation and posttranslational histone processing, have emerged as important regulators of immune …
In this regard, monocytes/macrophages are key players in the development of a chronic inflammatory state. Over the past decade …
Inflammatory Cells and Proteases in Abdominal Aortic Aneurysm and its Complications.
Jiang H, Sasaki T, Jin E, Kuzuya M, Cheng XW. Jiang H, et al. Curr Drug Targets. 2018;19(11):1289-1296. doi: 10.2174/1389450119666180531103458. Curr Drug Targets. 2018. PMID: 29848273 Review.
Abdominal aortic aneurysm (AAA), a common disease among elderly individuals, involves the progressive dilatation of the abdominal aorta as a consequence of degeneration. ...
Abdominal aortic aneurysm (AAA), a common disease among elderly individuals, involves the progressive dilatation of the
PARP-1 (Poly[ADP-Ribose] Polymerase 1) Inhibition Protects From Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysm in Mice.
Liang ES, Bai WW, Wang H, Zhang JN, Zhang F, Ma Y, Jiang F, Yin M, Zhang MX, Chen XM, Qin WD. Liang ES, et al. Hypertension. 2018 Nov;72(5):1189-1199. doi: 10.1161/HYPERTENSIONAHA.118.11184. Hypertension. 2018. PMID: 30354818
Abdominal aortic aneurysm (AAA) is a common vascular degenerative disease. PARP-1 (poly[ADP-ribose] polymerase 1) is a nuclear enzyme, which plays a critical role in vascular diseases. ...Genetic deletion of PARP-1 markedly reduced the AAA incidence, abdom
Abdominal aortic aneurysm (AAA) is a common vascular degenerative disease. PARP-1 (poly[ADP-ribose] polymerase 1) is a
Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.
Nakao T, Horie T, Baba O, Nishiga M, Nishino T, Izuhara M, Kuwabara Y, Nishi H, Usami S, Nakazeki F, Ide Y, Koyama S, Kimura M, Sowa N, Ohno S, Aoki H, Hasegawa K, Sakamoto K, Minatoya K, Kimura T, Ono K. Nakao T, et al. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2161-2170. doi: 10.1161/ATVBAHA.117.309768. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882868
OBJECTIVE: Abdominal aortic aneurysm (AAA) is an increasingly prevalent and ultimately fatal disease with no effective pharmacological treatment. ...Reduced macrophage accumulation and monocyte chemotactic protein-1 expression were observed in c …
OBJECTIVE: Abdominal aortic aneurysm (AAA) is an increasingly prevalent and ultimately fatal disease with no effective …
Transforming growth factor β neutralization finely tunes macrophage phenotype in elastase-induced abdominal aortic aneurysm and is associated with an increase of arginase 1 expression in the aorta.
Raffort J, Lareyre F, Clément M, Moratal C, Jean-Baptiste E, Hassen-Khodja R, Burel-Vandenbos F, Bruneval P, Chinetti G, Mallat Z. Raffort J, et al. J Vasc Surg. 2019 Aug;70(2):588-598.e2. doi: 10.1016/j.jvs.2018.09.045. Epub 2019 Feb 18. J Vasc Surg. 2019. PMID: 30792060
OBJECTIVE: Macrophages play a critical role in the initiation and progression of abdominal aortic aneurysm (AAA) and are classically distinguished into M1 "proinflammatory" and M2 "anti-inflammatory" macrophages. ...Monocyte-macrophage
OBJECTIVE: Macrophages play a critical role in the initiation and progression of abdominal aortic aneurysm (AAA) …
TROVE2 strengthens the anti-inflammatory effect via macrophage polarization by estrogen induction in abdominal aortic aneurysm.
Chen S, Zhao Y, Jin H, Qi X, He J, Huang J, Ding Y, Chen W, Wu C, Ding X, Chen S, Zhang H, Shang Y, Du D, Zhao J. Chen S, et al. Life Sci. 2020 Feb 1;242:117207. doi: 10.1016/j.lfs.2019.117207. Epub 2019 Dec 19. Life Sci. 2020. PMID: 31863777
Abdominal Aortic Aneurysm (AAA) is a severe cardiovascular disease, with high mortality rate after acute rupture of blood vessels. ...We focused on the role of monocytes/macrophages in the development of cardiovascular diseases to further explor
Abdominal Aortic Aneurysm (AAA) is a severe cardiovascular disease, with high mortality rate after acute rupture of blo
Inflammatory Mechanisms of Cardiovascular Remodeling.
Anzai T. Anzai T. Circ J. 2018 Feb 23;82(3):629-635. doi: 10.1253/circj.CJ-18-0063. Epub 2018 Feb 7. Circ J. 2018. PMID: 29415911 Free article. Review.
However, when an excessive inflammatory response consisting mainly of monocytes/macrophages is induced by various factors, impaired reparative fibrosis and resulting pathological remodeling processes may occur. A similar phenomenon is observed in abdominal
However, when an excessive inflammatory response consisting mainly of monocytes/macrophages is induced by various factors, imp …
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