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No evidence for prooxidative effects of homocysteine in vascular endothelial cells.
Frank J, Beck SC, Flaccus A, Biesalski HK. Frank J, et al. Eur J Nutr. 2007 Aug;46(5):286-92. doi: 10.1007/s00394-007-0663-x. Epub 2007 Jun 28. Eur J Nutr. 2007. PMID: 17599238
However, our results demonstrate that HCys had neither prooxidative nor cytotoxic effects on endothelial cells. Only a moderate time- and concentration-dependent increase in monocyte adhesion up to 28.3 +/- 5.5% was achieved relative to control after 4 …
However, our results demonstrate that HCys had neither prooxidative nor cytotoxic effects on endothelial cells. …
Vascular incompetence in dialysis patients--protein-bound uremic toxins and endothelial dysfunction.
Jourde-Chiche N, Dou L, Cerini C, Dignat-George F, Brunet P. Jourde-Chiche N, et al. Semin Dial. 2011 May-Jun;24(3):327-37. doi: 10.1111/j.1525-139X.2011.00925.x. Semin Dial. 2011. PMID: 21682773 Review.
Patients with CKD display impaired endothelium-dependent vasodilatation, elevated soluble biomarkers of endothelial dysfunction, and increased oxidative stress. They also present an imbalance between circulating endothelial populations reflecting endothelial
Patients with CKD display impaired endothelium-dependent vasodilatation, elevated soluble biomarkers of endothelial dysfunction, and …
Coronary artery disease--free radical damage, antioxidant protection and the role of homocysteine.
Maxwell SR. Maxwell SR. Basic Res Cardiol. 2000;95 Suppl 1:I65-71. doi: 10.1007/s003950070012. Basic Res Cardiol. 2000. PMID: 11192356 Review.
Established risk factors such as hypertension, smoking and diabetes mellitus are all associated with increased oxidative stresses due to excess free radical activity in the vascular wall. This may facilitate the development of vascular disease because of (i) increas …
Established risk factors such as hypertension, smoking and diabetes mellitus are all associated with increased oxidative stresses due to exc …