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Nonclassical Monocytes in Health and Disease.
Narasimhan PB, Marcovecchio P, Hamers AAJ, Hedrick CC. Narasimhan PB, et al. Annu Rev Immunol. 2019 Apr 26;37:439-456. doi: 10.1146/annurev-immunol-042617-053119. Annu Rev Immunol. 2019. PMID: 31026415 Review.
Nonclassical monocytes have been widely viewed as anti-inflammatory, as they maintain vascular homeostasis. ...This review focuses on the state of the monocyte biology field and the functions of monocytes, particularly nonclassical monocytes
Nonclassical monocytes have been widely viewed as anti-inflammatory, as they maintain vascular homeostasis. ...This review foc
Pattern of human monocyte subpopulations in health and disease.
Ożańska A, Szymczak D, Rybka J. Ożańska A, et al. Scand J Immunol. 2020 Jul;92(1):e12883. doi: 10.1111/sji.12883. Epub 2020 May 5. Scand J Immunol. 2020. PMID: 32243617 Free article. Review.
Based on the expression of superficial CD14 and CD16 in flow cytometry, they can be divided into three subsets: classical, intermediate and non-classical. Variation in the levels of human monocyte subsets in the blood can be observed in patients in numerous pathological st …
Based on the expression of superficial CD14 and CD16 in flow cytometry, they can be divided into three subsets: classical, intermediate and …
Role of Monocytes and Intestinal Macrophages in Crohn's Disease and Ulcerative Colitis.
Gren ST, Grip O. Gren ST, et al. Inflamm Bowel Dis. 2016 Aug;22(8):1992-8. doi: 10.1097/MIB.0000000000000824. Inflamm Bowel Dis. 2016. PMID: 27243595 Review.
In humans, 3 subsets of monocytes are described in blood with seemingly different functions, the classical (CD14CD16) monocytes, the intermediate (CD14CD16) monocytes, and the nonclassical (CD14CD16) monocytes. In the intestine, macrophages can …
In humans, 3 subsets of monocytes are described in blood with seemingly different functions, the classical (CD14CD16) monocytes
PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function.
Bianchini M, Duchêne J, Santovito D, Schloss MJ, Evrard M, Winkels H, Aslani M, Mohanta SK, Horckmans M, Blanchet X, Lacy M, von Hundelshausen P, Atzler D, Habenicht A, Gerdes N, Pelisek J, Ng LG, Steffens S, Weber C, Megens RTA. Bianchini M, et al. Sci Immunol. 2019 Jun 21;4(36):eaar3054. doi: 10.1126/sciimmunol.aar3054. Sci Immunol. 2019. PMID: 31227596
The role of nonclassical monocytes (NCMs) in health and disease is emerging, but their location and function within tissues remain poorly explored. ...Visualization of PD-L1(+) NCMs in relation to bone marrow vasculature reveals that conversion of clas …
The role of nonclassical monocytes (NCMs) in health and disease is emerging, but their location and function wit …
Monocyte subsets in man and other species.
Ziegler-Heitbrock L. Ziegler-Heitbrock L. Cell Immunol. 2014 May-Jun;289(1-2):135-9. doi: 10.1016/j.cellimm.2014.03.019. Epub 2014 Apr 8. Cell Immunol. 2014. PMID: 24791698 Review.
Monocytes are white blood cells that belong to the mononuclear phagocyte system. They derive from precursors in bone marrow, from there they go into blood, where they have a half-life of 1-2 days, and then they migrate into the various tissues. Monocyte subsets were
Monocytes are white blood cells that belong to the mononuclear phagocyte system. They derive from precursors in bone marrow, from the
6-Sulfo LacNAc (Slan) as a Marker for Non-classical Monocytes.
Hofer TP, van de Loosdrecht AA, Stahl-Hennig C, Cassatella MA, Ziegler-Heitbrock L. Hofer TP, et al. Front Immunol. 2019 Sep 13;10:2052. doi: 10.3389/fimmu.2019.02052. eCollection 2019. Front Immunol. 2019. PMID: 31572354 Free PMC article. Review.
We elaborate herein that the features of slan+ cells are congruent with the features of CD16+ non-classical monocytes and that slan is a candidate marker for definition of non-classical monocytes. The use of this marker may help in studying the role of non-classical …
We elaborate herein that the features of slan+ cells are congruent with the features of CD16+ non-classical monocytes and that slan i …
The immune potential and immunopathology of cytokine-producing B cell subsets: a comprehensive review.
Bao Y, Cao X. Bao Y, et al. J Autoimmun. 2014 Dec;55:10-23. doi: 10.1016/j.jaut.2014.04.001. Epub 2014 May 1. J Autoimmun. 2014. PMID: 24794622 Review.
On the other hand, they can negatively regulate immune responses by suppressing Th cell responses, inhibiting Tr1 cell and Foxp3(+) Treg differentiation, impairing APC function and pro-inflammatory cytokine release by monocytes, and inducing CD8(+) T cell anergy and CD4(+) …
On the other hand, they can negatively regulate immune responses by suppressing Th cell responses, inhibiting Tr1 cell and Foxp3(+) Treg dif …
In-Depth Proteomic Characterization of Classical and Non-Classical Monocyte Subsets.
Segura V, Valero ML, Cantero L, Muñoz J, Zarzuela E, García F, Aloria K, Beaskoetxea J, Arizmendi JM, Navajas R, Paradela A, Díez P, Dégano RM, Fuentes M, Orfao A, Montero AG, Garin-Muga A, Corrales FJ, Pino MMSD. Segura V, et al. Proteomes. 2018 Feb 5;6(1):8. doi: 10.3390/proteomes6010008. Proteomes. 2018. PMID: 29401756 Free PMC article.
Monocytes are bone marrow-derived leukocytes that are part of the innate immune system. ...These cells are key players in the inflammation process underlying the mechanism of many diseases. Thus, the molecular characterization of these cells may provide very useful
Monocytes are bone marrow-derived leukocytes that are part of the innate immune system. ...These cells are key players in the inflamm
Reprint of: Monocyte subsets in man and other species.
Ziegler-Heitbrock L. Ziegler-Heitbrock L. Cell Immunol. 2014 Sep-Oct;291(1-2):11-5. doi: 10.1016/j.cellimm.2014.06.008. Epub 2014 Jul 9. Cell Immunol. 2014. PMID: 25015741
Monocytes are white blood cells that belong to the mononuclear phagocyte system. They derive from precursors in bone marrow, from there they go into blood, where they have a half-life of 1-2 days, and then they migrate into the various tissues. Monocyte subsets were
Monocytes are white blood cells that belong to the mononuclear phagocyte system. They derive from precursors in bone marrow, from the
Toward a refined definition of monocyte subsets.
Ziegler-Heitbrock L, Hofer TP. Ziegler-Heitbrock L, et al. Front Immunol. 2013 Feb 4;4:23. doi: 10.3389/fimmu.2013.00023. eCollection 2013. Front Immunol. 2013. PMID: 23382732 Free PMC article.
In a nomenclature proposal published in 2010 monocytes were subdivided into classical and non-classical cells and in addition an intermediate monocyte subset was proposed. ...While these cells appear to be in transition from classical to non-classical monocytes
In a nomenclature proposal published in 2010 monocytes were subdivided into classical and non-classical cells and in addition an inte …
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