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Octamer binding factors and their coactivator can activate the murine PU.1 (spi-1) promoter.
Chen H, Zhang P, Radomska HS, Hetherington CJ, Zhang DE, Tenen DG. Chen H, et al. J Biol Chem. 1996 Jun 28;271(26):15743-52. doi: 10.1074/jbc.271.26.15743. J Biol Chem. 1996. PMID: 8663022 Free article.
PU.1 (spi-1), a member of the Ets transcription factor family, is predominantly expressed in myeloid and B cells, activates many B cell and myeloid genes, and is critical for development of both of these lineages. ...We also demonstrate t
PU.1 (spi-1), a member of the Ets transcription factor family, is predominantly expressed in myeloid and
Lymphoid- and myeloid-specific activity of the PU.1 promoter is determined by the combinatorial action of octamer and ets transcription factors.
Kistler B, Pfisterer P, Wirth T. Kistler B, et al. Oncogene. 1995 Sep 21;11(6):1095-106. Oncogene. 1995. PMID: 7566969
The putative oncogene PU.1/Spi-1 is a member of the ets-family of transcription factors normally expressed in a subset of hematopoietic cell types. ...Interestingly, the PU.1 transcription factor can functionally interact wi …
The putative oncogene PU.1/Spi-1 is a member of the ets-family of transcription factors normally expresse …
Btk expression is controlled by Oct and BOB.1/OBF.1.
Brunner C, Wirth T. Brunner C, et al. Nucleic Acids Res. 2006 Mar 31;34(6):1807-15. doi: 10.1093/nar/gkl131. Print 2006. Nucleic Acids Res. 2006. PMID: 16582106 Free PMC article.
Mice deficient for the transcriptional coactivator BOB.1/OBF.1 show several defects in differentiation, function and signaling of B cells. ...This in turn leads to the induction of Btk promoter activity in synergism with the transcription
Mice deficient for the transcriptional coactivator BOB.1/OBF.1 show several defects in differentiation, function