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Oxidized lipoproteins are associated with markers of inflammation and immune activation in HIV-1 infection.
Kelesidis T, Jackson N, McComsey GA, Wang X, Elashoff D, Dube MP, Brown TT, Yang OO, Stein JH, Currier JS. Kelesidis T, et al. AIDS. 2016 Nov 13;30(17):2625-2633. doi: 10.1097/QAD.0000000000001238. AIDS. 2016. PMID: 27603288 Free PMC article.
OBJECTIVE: The pathogenesis of immune dysfunction in chronic HIV-1 infection is unclear, and a potential role for oxidized lipids has been suggested. ...Positive associations were observed at baseline and over time between HDLox (but not …
OBJECTIVE: The pathogenesis of immune dysfunction in chronic HIV-1 infection is unclear, and a potential role fo …
Diabetes and dyslipidaemia are associated with oxidative stress independently of inflammation in long-term antiretroviral-treated HIV-infected patients.
Bastard JP, Couffignal C, Fellahi S, Bard JM, Mentre F, Salmon D, Katlama C, Raffi F, Leport C, Capeau J; ANRS CO, APROCO-COPILOTE Cohort study group. Bastard JP, et al. Diabetes Metab. 2019 Dec;45(6):573-581. doi: 10.1016/j.diabet.2019.02.008. Epub 2019 Mar 9. Diabetes Metab. 2019. PMID: 30862472
Also measured were circulating biomarkers to explore oxidative stress (Lp-PLA2, oxLDL, oxLDL/LDL ratio, paraoxonase and arylesterase activities), inflammation/immune activation (hsCRP, hsIL-6, D dimer, soluble CD14, β2 microglobulin, cyst …
Also measured were circulating biomarkers to explore oxidative stress (Lp-PLA2, oxLDL, oxLDL/LDL ratio, paraoxonase and aryles …
Effects of pitavastatin and pravastatin on markers of immune activation and arterial inflammation in HIV.
Toribio M, Fitch KV, Sanchez L, Burdo TH, Williams KC, Sponseller CA, McCurdy Pate M, Aberg JA, Zanni MV, Grinspoon SK. Toribio M, et al. AIDS. 2017 Mar 27;31(6):797-806. doi: 10.1097/QAD.0000000000001427. AIDS. 2017. PMID: 28252528 Free PMC article. Clinical Trial.
We aimed to compare the effects of two key statins on markers of systemic immune activation and arterial inflammation in the HIV population. ...CONCLUSION: Fifty-two weeks of pitavastatin 4 mg daily (vs. pravastatin 40 mg daily) led to a greater …
We aimed to compare the effects of two key statins on markers of systemic immune activation and arterial inflammatio
Effects of atorvastatin on biomarkers of immune activation, inflammation, and lipids in virologically suppressed, human immunodeficiency virus-1-infected individuals with low-density lipoprotein cholesterol <130 mg/dL (AIDS Clinical Trials Group Study A5275).
Nixon DE, Bosch RJ, Chan ES, Funderburg NT, Hodder S, Lake JE, Lederman MM, Klingman KL, Aberg JA; AIDS Clinical Trials Group Study A5275 Team. Nixon DE, et al. J Clin Lipidol. 2017 Jan-Feb;11(1):61-69. doi: 10.1016/j.jacl.2016.09.017. Epub 2016 Oct 5. J Clin Lipidol. 2017. PMID: 28391912 Free PMC article. Clinical Trial.
BACKGROUND: Persistent immune activation and inflammation in virologically suppressed human immunodeficiency virus (HIV) infection are linked to excess cardiovascular risk. ...CONCLUSION: In virologically suppressed individuals with HIV
BACKGROUND: Persistent immune activation and inflammation in virologically suppressed human immunodeficiency virus ( …
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