Temporal autoregulation during human PU.1 locus SubTAD formation.
Schuetzmann D, Walter C, van Riel B, Kruse S, König T, Erdmann T, Tönges A, Bindels E, Weilemann A, Gebhard C, Wethmar K, Perrod C, Minderjahn J, Rehli M, Delwel R, Lenz G, Gröschel S, Dugas M, Rosenbauer F.
Schuetzmann D, et al.
Blood. 2018 Dec 20;132(25):2643-2655. doi: 10.1182/blood-2018-02-834721. Epub 2018 Oct 12.
Blood. 2018.
PMID: 30315124
Free article.
We identified a dynamic 75-kb unit (SubTAD) as the genomic region in which spatial interactions between PU.1 gene regulatory elements occur during myeloid differentiation and are interrupted in AML. ...However, once these spatial interactions have occu …
We identified a dynamic 75-kb unit (SubTAD) as the genomic region in which spatial interactions between PU.1 gene regul …