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PU.1 (Spi-1) autoregulates its expression in myeloid cells.
Chen H, Ray-Gallet D, Zhang P, Hetherington CJ, Gonzalez DA, Zhang DE, Moreau-Gachelin F, Tenen DG. Chen H, et al. Oncogene. 1995 Oct 19;11(8):1549-60. Oncogene. 1995. PMID: 7478579
PU.1 (Spi-1), a member of the Ets transcription factor family, is predominantly expressed in myeloid (granulocytes, monocytes and macrophages) and B cells. ...Positive autoregulation of the PU.1 promoter may pl
PU.1 (Spi-1), a member of the Ets transcription factor family, is predominantly expressed in myeloid
Function of PU.1 (Spi-1), C/EBP, and AML1 in early myelopoiesis: regulation of multiple myeloid CSF receptor promoters.
Zhang DE, Hohaus S, Voso MT, Chen HM, Smith LT, Hetherington CJ, Tenen DG. Zhang DE, et al. Curr Top Microbiol Immunol. 1996;211:137-47. doi: 10.1007/978-3-642-85232-9_14. Curr Top Microbiol Immunol. 1996. PMID: 8585944 Review.
Similarly, expression of PU.1 activates its own promoter, and turns on the three myeloid CSF receptors (M, GM, and G), pushing these cells along the pathway of myeloid differentiation. ...Myeloid genes expressed later during …
Similarly, expression of PU.1 activates its own promoter, and turns on the three myeloid CSF receptors (M, GM, a …
Potential autoregulation of transcription factor PU.1 by an upstream regulatory element.
Okuno Y, Huang G, Rosenbauer F, Evans EK, Radomska HS, Iwasaki H, Akashi K, Moreau-Gachelin F, Li Y, Zhang P, Göttgens B, Tenen DG. Okuno Y, et al. Mol Cell Biol. 2005 Apr;25(7):2832-45. doi: 10.1128/MCB.25.7.2832-2845.2005. Mol Cell Biol. 2005. PMID: 15767686 Free PMC article.
Regulation of the hematopoietic transcription factor PU.1 (Spi-1) plays a critical role in the development of white cells, and abnormal expression of PU.1 can lead to leukemia. We previously reported that the PU.1
Regulation of the hematopoietic transcription factor PU.1 (Spi-1) plays a critical role in the development of wh …
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