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Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA-DR expression.
Connaughton EP, Naicker S, Hanley SA, Slevin SM, Eykelenboom JK, Lowndes NF, O'Brien T, Ceredig R, Griffin MD, Dennedy MC. Connaughton EP, et al. Immunol Cell Biol. 2018 Mar 5. doi: 10.1111/imcb.12032. Online ahead of print. Immunol Cell Biol. 2018. PMID: 29505094
In this study, it was shown that conventionally defined human intermediate monocytes can be divided into two distinct subpopulations with mid- and high-level surface expression of HLA-DR (referred to as DR(mid) and DR(hi) …
In this study, it was shown that conventionally defined human intermediate monocytes can be divided into two distinct s …
A Novel, Five-Marker Alternative to CD16-CD14 Gating to Identify the Three Human Monocyte Subsets.
Ong SM, Teng K, Newell E, Chen H, Chen J, Loy T, Yeo TW, Fink K, Wong SC. Ong SM, et al. Front Immunol. 2019 Jul 26;10:1761. doi: 10.3389/fimmu.2019.01761. eCollection 2019. Front Immunol. 2019. PMID: 31402918 Free PMC article.
Human primary monocytes are heterogeneous in terms of phenotype and function, but are sub-divided only based on CD16 and CD14 expression. CD16 expression distinguishes a subset of monocytes with highly pro-inflammator
Human primary monocytes are heterogeneous in terms of phenotype and function, but are sub-divided only
Circulating CD33+ large mononuclear cells contain three distinct populations with phenotype of putative antigen-presenting cells including myeloid dendritic cells and CD14+ monocytes with their CD16+ subset.
Fagnoni FF, Oliviero B, Zibera C, Gibelli N, Lozza L, Vescovini R, Sansoni P, Zambelli A, DaPrada G, Robustelli della Cuna G. Fagnoni FF, et al. Cytometry. 2001 Oct 1;45(2):124-32. doi: 10.1002/1097-0320(20011001)45:2<124::aid-cyto1154>3.0.co;2-l. Cytometry. 2001. PMID: 11590624 Free article.
Similarly, HLA-class II DR expression usually identifies mononuclear cells with the potential for developing antigen-presenting activity. ...Interestingly, CD2+CD14- cells within the My-APC gate were equivalent to myeloid dendritic cell precursors (pre-DC) de …
Similarly, HLA-class II DR expression usually identifies mononuclear cells with the potential for developing antigen-pr …