Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression.
J Biol Chem. 2007.
PMID: 17303559
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Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression.
J Biol Chem. 2007 Apr 20;282(16):11629-38. doi: 10.1074/jbc.M611418200. Epub 2007 Feb 15.
J Biol Chem. 2007.
PMID: 17303559
Free article.
The tumor necrosis factor (TNF) gene is activated by multiple extracellular signals in a stimulus- and cell type-specific fashion. ...We conclude that induction of TNF gene transcription by virus or LPS does not depend upon …
The tumor necrosis factor (TNF) gene is activated by multiple extracellular signals in a stimulus- and ce …
Stimulus-specific induction of a novel nuclear factor-kappaB regulator, IkappaB-zeta, via Toll/Interleukin-1 receptor is mediated by mRNA stabilization.
J Biol Chem. 2005 Jan 14;280(2):1678-87. doi: 10.1074/jbc.M409983200. Epub 2004 Nov 2.
J Biol Chem. 2005.
PMID: 15522867
Free article.
To examine post-transcriptional regulation, we analyzed the decay of IkappaB-zeta mRNA, and we found that it was specifically stabilized by lipopolysaccharide or IL-1beta but not by TNF-alpha. ...Because IkappaB-zeta is essential for expressi …
To examine post-transcriptional regulation, we analyzed the decay of IkappaB-zeta mRNA, and we found that it was spe …
Cell type and stimulus specific regulation of chemokine gene expression.
Biochem Biophys Res Commun. 1994 Jan 28;198(2):590-6. doi: 10.1006/bbrc.1994.1086.
Biochem Biophys Res Commun. 1994.
PMID: 8297369
KC mRNA was only expressed in BALB/c 3T3 cells stimulated by IL-1 alpha. ...Nevertheless, the mechanisms involved in the induction of each gene varied with the stimulus and involved both transcriptional and post-transcriptional com …
KC mRNA was only expressed in BALB/c 3T3 cells stimulated by IL-1 alpha. ...Nevertheless, the mechanisms involved in th …
A cis-element in the 3'-untranslated region of IkappaB-zeta mRNA governs its stimulus-specific expression.
Biochem Biophys Res Commun. 2007 May 11;356(3):785-91. doi: 10.1016/j.bbrc.2007.03.044. Epub 2007 Mar 16.
Biochem Biophys Res Commun. 2007.
PMID: 17382899
IkappaB-zeta, an essential transcriptional regulator in inflammatory reactions, is induced by microbial substances that stimulate Toll-like receptors and interleukin (IL)-1beta but not by tumor necrosis factor (TNF)-alpha, via specific …
IkappaB-zeta, an essential transcriptional regulator in inflammatory reactions, is induced by microbial substances that stimulate Tol …
Contribution of MKP-1 regulation of p38 to endotoxin tolerance.
Shock. 2005 Jan;23(1):80-7. doi: 10.1097/01.shk.0000145206.28812.60.
Shock. 2005.
PMID: 15614136
LPS-induced expression of TNF-alpha is partly regulated by the p38 mitogen-activated protein (MAP) kinase, which post-transcriptionally stabilizes TNF-alpha mRNA. ...We hypothesized that MKP-1 expression induced during tolerance …
LPS-induced expression of TNF-alpha is partly regulated by the p38 mitogen-activated protein (MAP) kinase, which pos …
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