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Proinflammatory properties of the human S100 protein S100A12.
Yang Z, Tao T, Raftery MJ, Youssef P, Di Girolamo N, Geczy CL. Yang Z, et al. J Leukoc Biol. 2001 Jun;69(6):986-94. J Leukoc Biol. 2001. PMID: 11404386
S100 proteins represent a new class of chemoattractants. Here we extend earlier evidence for the proinflammatory properties of human S100A12. ...
S100 proteins represent a new class of chemoattractants. Here we extend earlier evidence for the proinflammatory pro
S100 Calgranulins in inflammatory arthritis.
Perera C, McNeil HP, Geczy CL. Perera C, et al. Immunol Cell Biol. 2010 Jan;88(1):41-9. doi: 10.1038/icb.2009.88. Epub 2009 Nov 24. Immunol Cell Biol. 2010. PMID: 19935766 Review.
Calgranulins comprise three proteins, S100A8 (Calgranulin A), S100A9 (Calgranulin B) and S100A12 (Calgranulin C) that are predominantly expressed by neutrophils, monocytes and activated macrophages. These S100 calcium-binding proteins are important mol …
Calgranulins comprise three proteins, S100A8 (Calgranulin A), S100A9 (Calgranulin B) and S100A12 (Calgranulin C) that are pred …
S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
Chung YM, Goyette J, Tedla N, Hsu K, Geczy CL. Chung YM, et al. PLoS One. 2013 Apr 24;8(4):e62372. doi: 10.1371/journal.pone.0062372. Print 2013. PLoS One. 2013. PMID: 23638054 Free PMC article.
Serum amyloid A induces monocyte cytokines and tissue factor. S100A12 did not stimulate IL-6, IL-8, IL-1beta or TNF-alpha production by human peripheral blood mononuclear cells but low amounts consistently reduced cytokine mRNA and protein levels induced by s …
Serum amyloid A induces monocyte cytokines and tissue factor. S100A12 did not stimulate IL-6, IL-8, IL-1beta or TNF-alpha production …
Neutrophil derived human S100A12 (EN-RAGE) is strongly expressed during chronic active inflammatory bowel disease.
Foell D, Kucharzik T, Kraft M, Vogl T, Sorg C, Domschke W, Roth J. Foell D, et al. Gut. 2003 Jun;52(6):847-53. doi: 10.1136/gut.52.6.847. Gut. 2003. PMID: 12740341 Free PMC article.
S100A12 is a calcium binding protein with proinflammatory properties. ...S100A12 serum concentrations were analysed using a sandwich ELISA. ...
S100A12 is a calcium binding protein with proinflammatory properties. ...S100A12 serum concentrations wer
Inflammation-associated S100 proteins: new mechanisms that regulate function.
Goyette J, Geczy CL. Goyette J, et al. Amino Acids. 2011 Oct;41(4):821-42. doi: 10.1007/s00726-010-0528-0. Epub 2010 Mar 6. Amino Acids. 2011. PMID: 20213444 Review.
S100A12 activates mast cells and is a monocyte and mast cell chemoattractant; a G-protein-coupled mechanism may be involved. ...In summary, S100A12 has pro-inflammatory properties that are likely to be stable in an oxidative environment, because it lac
S100A12 activates mast cells and is a monocyte and mast cell chemoattractant; a G-protein-coupled mechanism may be involved. .
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