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Prostacyclin analogs suppress the synthesis of tumor necrosis factor-alpha in LPS-stimulated human peripheral blood mononuclear cells.
Eisenhut T, Sinha B, Gröttrup-Wolfers E, Semmler J, Siess W, Endres S. Eisenhut T, et al. Immunopharmacology. 1993 Nov-Dec;26(3):259-64. doi: 10.1016/0162-3109(93)90042-o. Immunopharmacology. 1993. PMID: 7507098
Recent reports have shown that prostaglandin E2 (PGE2) is able to suppress lipopolysaccharide (LPS)-stimulated production of tumor necrosis factor-alpha (TNF-alpha). ...Moreover, the prostacyclin analogs as wel …
Recent reports have shown that prostaglandin E2 (PGE2) is able to suppress lipopolysaccharide (LPS)-stimulated producti …
Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids.
Sinha B, Semmler J, Eisenhut T, Eigler A, Endres S. Sinha B, et al. Eur J Immunol. 1995 Jan;25(1):147-53. doi: 10.1002/eji.1830250125. Eur J Immunol. 1995. PMID: 7843225
We investigated cooperative effects of phosphodiesterase (PDE) inhibitors and prostanoids on cyclic adenosine monophosphate (cAMP) accumulation and tumor necrosis factor (TNF)-alpha synthesis in human peripheral blood mon
We investigated cooperative effects of phosphodiesterase (PDE) inhibitors and prostanoids on cyclic adenosine monophosphate (cAMP) accumulat …
Anti-inflammatory activities of cAMP-elevating agents: enhancement of IL-10 synthesis and concurrent suppression of TNF production.
Eigler A, Siegmund B, Emmerich U, Baumann KH, Hartmann G, Endres S. Eigler A, et al. J Leukoc Biol. 1998 Jan;63(1):101-7. doi: 10.1002/jlb.63.1.101. J Leukoc Biol. 1998. PMID: 9469479
Interleukin-10 (IL-10) and tumor necrosis factor (TNF) exert key roles in some acute and chronic inflammatory diseases. In this study we investigated (1) the potency of different cAMP-elevating agents in enhancing IL-10 synthesis, (2) the involvement o …
Interleukin-10 (IL-10) and tumor necrosis factor (TNF) exert key roles in some acute and chronic inflammatory diseases. …
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