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RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium.
von Hundelshausen P, Weber KS, Huo Y, Proudfoot AE, Nelson PJ, Ley K, Weber C. von Hundelshausen P, et al. Circulation. 2001 Apr 3;103(13):1772-7. doi: 10.1161/01.cir.103.13.1772. Circulation. 2001. PMID: 11282909
We show that RANTES secreted by thrombin-stimulated platelets is immobilized on the surface of inflamed microvascular or aortic endothelium and triggers shear-resistant monocyte arrest under flow conditions, as shown by inhibition …
We show that RANTES secreted by thrombin-stimulated platelets is immobilized on the surface of inflamed microvascular o …
Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium.
Mause SF, von Hundelshausen P, Zernecke A, Koenen RR, Weber C. Mause SF, et al. Arterioscler Thromb Vasc Biol. 2005 Jul;25(7):1512-8. doi: 10.1161/01.ATV.0000170133.43608.37. Epub 2005 May 12. Arterioscler Thromb Vasc Biol. 2005. PMID: 15890969
We studied the role of PMPs in delivering RANTES and promoting monocyte recruitment. METHODS AND RESULTS: Here we show that PMPs contain substantial amounts of RANTES and deposit RANTES on activated endothelium or murine atheroscleroti
We studied the role of PMPs in delivering RANTES and promoting monocyte recruitment. METHODS AND RESULTS: Here we show that PM …
Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury.
Schober A, Manka D, von Hundelshausen P, Huo Y, Hanrath P, Sarembock IJ, Ley K, Weber C. Schober A, et al. Circulation. 2002 Sep 17;106(12):1523-9. doi: 10.1161/01.cir.0000028590.02477.6f. Circulation. 2002. PMID: 12234959
BACKGROUND: Chemokines expressed on atherosclerotic endothelium or deposited by activated platelets have been implicated in monocyte recruitment during atherogenesis and restenosis. ...METHODS AND RESULTS: Using immunofluorescence and laminar fl …
BACKGROUND: Chemokines expressed on atherosclerotic endothelium or deposited by activated platelets have been im …
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